Been on TRT for 5 Weeks and I'm Very Worried

Hello,

I’ve missed out some facts,

All my life I’ve had gynocomastia, my bloods show my estrogen is high and my proc is through the roof, should I look into arimidex also as caber? Can these be used together? Also hear HCG makes estrogen higher so should I leave that now? I also want kids in the future or am I infertile now from. Results?

Cheers

Nolvadex would the med for gyno, or Letrozole but is more harsh and can affect libido

Can that be used along side trt?

Definitely

Because the medication he is being told to take without any prescription can shrink any pituitary tumours, meaning if he does get an MRI at some point in the future it is making it harder to diagnose and if there is a problem, you are compromising him ever getting correct treatment.

His high prolactin is more likely to be to the ridiculously high E2.

Treat the source of the problem - lower the E2 and see what happens to the prolactin. If it doesn’t fall with E2, get the scan. Just like his medical professional advised.

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You can start with about 20 mg/day then ramp up to 40/day if needed. Gyno reversal isn’t instantaneous and may never go away completely without surgery, so be patient.

Lowering e2… Is thst what nolva/arimidex is for?

They are 2 different things. Arimidex is an aromatase inhibitor (AI) and Nolva is a selective estrogen receptor modulator (SERM). AIs stop T from becoming E and SERMs prevent E from attaching themselves to breast tissue cells but allow the good things that E provide to still happen.

No man you have it backwards, a prolactinoma is a prolactin secreting adenoma.

What do I have backwards?

You are saying the prolactin his caused by high estradiol but the prolactin is directly secreted from the adenoma.

E2 has no relation except that it can spur tissue growth.

Micro-prolactinomas are only the size of the end of pen tip. So they do not warrant surgery, the risks outweigh the benefits.

So there is nothing wrong with him taking the dopamine agonist, in fact it is exactly what the endocrinologist would prescribe upon diagnosis.

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I don’t know what your link means or is trying to say, if you could extrapolate on it in your own words that would be great.

Thanks

If you can’t read it I cant help you.

I’ve also explained why its an issue to self diagnose a dopamine agonist. Recommending people to buy prescription drugs off the internet is ludicrous advice.

Here’s another to read if you can

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You are so right @lenono This thread just made me disgusted with the bro science being thrown around. I’ve lost confidence in any advice from @increasemyt as he can’t even read a damn study presented to him. Meanwhile he’s in the TRT biz :joy:

It makes perfect sense why @increasemyt was attacking @yeti308 and that other guy Daniel. You don’t take to well with opposing views

Lmao

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I never recommended he buy prescription drugs off the internet. Also your first article talks about VTR, I don’t know if you are having trouble reading or you pasted the incorrect link.

As for your second article, are you insinuating the OP is pregnant?

No, high estrogen due to taking exogenous testosterone.

A long list of other compounds may determine an increase in prolactin levels, including prokinetics, opiates, estrogens, anti-androgens, anti-hypertensive drugs, H2-receptor antagonists, anti-convulsivants and cholinomimetics.

  1. High Estradiol. It is no secret that, if you increase estradiol, you will increase prolactin release. [2] Some of the older research showed that this effect was dose dependent, i.e. the more estradiol you added, the higher prolactin increased. [3] And researchers have discovered one of the key mechanisms: estradiol regulates the transcription of the prolactin gene . [4] So, if you are on the high side with prolactin, one of the first things you should probably pull is estradiol. Remember that, as men, we need the appropriate LC-MS/MS test that can pick up our relatively low levels of estradiol (compared to a female)

Like I said you are confused, it is not the high estrogen that causes high prolactin when you have a micro prolactinoma. We are not talking marginally high here, it is outrageous. You could argue that prolonged exposure to high E2 caused the adenoma, but you cannot argue that aromatase inhibitors will bring PRL down, because it won’t, if its being secreted from the tumor. You have latched on to an internet myth about guys running 19 nors and tried to extrapolate it to hyperprolactinemia. It is not the same

This is very common, as noted in your research, and was probably why the patient needed TRT to begin with.

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Mister know it all…,