I listened to an interview with Crisler extoling the benefits of GHRP-6 for anti-aging purposes. Most of the posts over in the steroid forum are using higher or more frequent doses than the 100mcg before bed that Crisler recommends. The cost is minimal and the more I read about the decrease in natural GH as we age, the more intrigued I am.
I have read a lot of posts, but too few of them from a stricly anti-aging viewpoint. I am just curious if anyone here is using it or has tried it?
[quote]Undone wrote:
I listened to an interview with Crisler extoling the benefits of GHRP-6 for anti-aging purposes. Most of the posts over in the steroid forum are using higher or more frequent doses than the 100mcg before bed that Crisler recommends. The cost is minimal and the more I read about the decrease in natural GH as we age, the more intrigued I am.
I have read a lot of posts, but too few of them from a stricly anti-aging viewpoint. I am just curious if anyone here is using it or has tried it?[/quote]
Apparently, the benefits decrease as you up the dose (at bedtime, usually) - those guys are just wasting it and doing who knows what else; listen to Dr. Crisler; he’s the best in the business and I’m proud to say he’s my doc.
I’m on TRT - my IGF-1 numbers don’t justify my trying GHRP-6 to bump up GH yet.
Some guys who have very low fasting insulin (like myself), don’t see a large increase in their IGF - but they experience a remarkable increase in feelings of well being.
The best part of this stuff is that it doesn’t shut down your own production; lets your own system self-regulate, etc.
[quote]katzenjammer wrote:
[quote]Undone wrote:
I listened to an interview with Crisler extoling the benefits of GHRP-6 for anti-aging purposes. Most of the posts over in the steroid forum are using higher or more frequent doses than the 100mcg before bed that Crisler recommends. The cost is minimal and the more I read about the decrease in natural GH as we age, the more intrigued I am.
I have read a lot of posts, but too few of them from a stricly anti-aging viewpoint. I am just curious if anyone here is using it or has tried it?[/quote]
Apparently, the benefits decrease as you up the dose (at bedtime, usually) - those guys are just wasting it and doing who knows what else; listen to Dr. Crisler; he’s the best in the business and I’m proud to say he’s my doc.
I’m on TRT - my IGF-1 numbers don’t justify my trying GHRP-6 to bump up GH yet.
Some guys who have very low fasting insulin (like myself), don’t see a large increase in their IGF - but they experience a remarkable increase in feelings of well being.
The best part of this stuff is that it doesn’t shut down your own production; lets your own system self-regulate, etc.
[/quote]
That was one of the things Crisler talked about that stood out in my mind. Some of his patients were not really showing a large increase in their numbers, but are reaping benefits nonetheless.
GHRP-6 can really over stimulate hunger for some and that could cause fat gain or block fat loss.
[quote]KSman wrote:
GHRP-6 can really over stimulate hunger for some and that could cause fat gain or block fat loss.[/quote]
Doesn’t the hunger stimulation come from a revved up metabolism?
[quote]katzenjammer wrote:
[quote]KSman wrote:
GHRP-6 can really over stimulate hunger for some and that could cause fat gain or block fat loss.[/quote]
Doesn’t the hunger stimulation come from a revved up metabolism?[/quote]
From what I have read and heard, KSman is right (as usual), but it typically comes with larger and/or more frequent doses. Crisler seem to indicate that approx. 100mcg at night did not lead to that for most of his patients. Some were able to increase dosage from there, while a few needed to back it off to 75mcg or so. It seemed right at 100mcg was the sweet spot for anti-aging purposes.
[quote]bushidobadboy wrote:
[quote]katzenjammer wrote:
Doesn’t the hunger stimulation come from a revved up metabolism?[/quote]
Not at all, and I also resent your comments directed towards the steroid forum users.
If you had bothered to research the subject a little more than just blindly following Dr Crisler, you might appreciate some of the mechanisms of action of GHRP6.
The appetite increase comes from reduction of gut transit time, caused by release of various hormones such as ghrelin, which increases gastric motility.
Now whilst GHRP6 in larger doses… actually I don’t know why I’m bothering to tell you about higher doses. It is clearly outside your area of interest.
Sorry if I sound like I’m pissed off. I know you (katzenjammer) from old and I considered you to be a reasonable, intelligent guy. You disappoint me with your attitude in this thread.
BBB[/quote]
Hey Bushy,
I’m sincerely sorry if I’ve offended anyone, you included.
All of this stuff falls well and far outside my area of expertise and, it’s true, I am basing my comments on my understanding of Dr. Crisler’s knowledge and experience regarding GHRP-6. What I meant to say was, I have heard him say on a number of occasions that - in his experience - there are rapidly diminishing marginal returns to increasing the dosage.
I could be mistaken about his opinion; and, of course, his opinion may be wrong. I was just passing it along.
No harm intended.
~katz
100 mcg is said to be the ‘saturation dose’ above this benefits are increased but at a diminishing rate. For physique purposes 100-200mcg 3x per day seems to be ideal. (bedtime, upon waking and post workout). Always on an empty stomach (at least an hour after eating and 30 min before eating). I would not take it without adding some cjc-1295 as it greatly increases the magnitude of the GH pulse.
For anti aging 100mcg of both the GHRP-6 and the cjc before bed should be sufficient. Bushido is right it is the ghrelin that increases the hunger. Many find that after a couple of weeks on the hunger is easier to control.
[quote]kaaizen wrote:
100 mcg is said to be the ‘saturation dose’ above this benefits are increased but at a diminishing rate. For physique purposes 100-200mcg 3x per day seems to be ideal. (bedtime, upon waking and post workout). Always on an empty stomach (at least an hour after eating and 30 min before eating). I would not take it without adding some cjc-1295 as it greatly increases the magnitude of the GH pulse.
For anti aging 100mcg of both the GHRP-6 and the cjc before bed should be sufficient. Bushido is right it is the ghrelin that increases the hunger. Many find that after a couple of weeks on the hunger is easier to control. [/quote]
What additional benefits do guys find at those doses? Decreased recovery time?
Also, when injecting two peptides, do you simply load both on one syringe and inject simultaneously or is that a bad idea?
[quote]bushidobadboy wrote:
Fair enough. I have had a shower since I posted above and managed to wash the sand from outwith my vaginal orifice.
BBB[/quote]
No - you were right to call me out.
Still, in any event, 'tis good to keep thy vaginal orifice clean! kidding, kidding… 
It is ok to mix both peptides in the same pin. Keep the peptides frozen until you add the Bac. water then keep in refrigerator. A higher dose results in a higher GH pulse. Basically you can expect the same results as running a GH cycle.
[quote]bushidobadboy wrote:
Fair enough. I have had a shower since I posted above and managed to wash the sand from outwith my vaginal orifice.
BBB[/quote]
BBB, sorry if it was my reference to the steroid forum that was offensive to you, as that was not my intent at all. I did spent a fair amount of time reading through that forum, including many of your posts regarding GHRP-6. Your comments reflect a great deal of knowledge and experience which I have always appreciated, as have obviously many others. In addition to the posts on this site, I also read every post from DatBtrue at another site regarding GHRP-6. It is extremely informative if others are interested.
My purpose for posting here was Crisler has a number of patients who frequent this forum, and I thought someone might be following his protocol. I was curious to see what “real world” results they were experiencing. If I was going to “blindly” follow Crisler’s recommendation, I don’t think I would have posted my original question.
Anyone have any opinions or experience regarding Ipamorelin?
Low doses of hexarelin have some interesting synergistic effects with CJ-1295. Hex doses need to below the amount that leads to hexarelin resistance.