Will proviron lessen your gains on a cycle? Just wondering because most people say it will compete with the same receptors that the other roids do, thus hindering gains.
No. If Proviron did bind to the androgen receptors in muscle this would be useful. All androgens are “full agonists”… if they are bound to the receptor they are all just as good as each other. It is like turning on a light switch: the receptor is activated, or not. It changes to the conformation that makes it bind to DNA and increase mRNA synthesis and therefore protein synthesis: or it does not.
There is never an issue of reducing effect of anabolic steroids by adding more anabolic steroids of a different kind.