I had my dht at 260, the range is 8-85 or something similar. My prostate was not enlarged, at least was not causing me issues. I believe something else is at play other than dht to cause prostate enlargment
Your doctor sounds incompetent, this statement is blasphemy in the world of hormone optimization! It doesnât sound like to me you are working with a doctor that understand hormones very well.
You need a doctor that thinks outside the box, you usually will not find these types of doctors in managed healthcare.
Some people are more susceptible to damage from starvation which is likely do to DNA.
Can the fact that I was fat (obese) until 17 year old can be linked with dna?
I know what has happened to you, the same thing that happened to me about 10 years ago. Being a programmer, I researched like crazy for answers and found none. Like you, my symptoms aligned with post-finasteride syndrome. Every symptom you mention was identical to mine, I never took the drug either (or anything similar).
Here is my take on what has happened to you - the swelling within your scrotum is a varicocele (which I also got on the left side, for you right), a lot of research indicates that it elevates liver enzymes that are responsible for progesterone synthesis. Progesterone by its very nature in males blocks the activity of E2 and DHT. Itâs not abnormal to have normal levels in blood, but have issues at a cellular level due to this activity occurring. This happens locally at prostate/genital area, for the body to âprotectâ the prostate from back flow from the testicles (and high levels of testosterone/DHT/E2 that hit the prostate due to varicocele or testicular abnormalities), progesterone acts locally to block the effects and damage (inflammation) that could be caused to the prostate.
Similarly the leaking urine, is due to pelvic floor dysfunction due to hormonal fluctuations that are now occurring in that area of the body. Due to time restraints while typing this message, I canât link every study but believe me when I say this - they do exist and prove these âtheoriesâ and Iâve researched this for years.
So the big question is how do you solve it? Similar studies indicate that taking external (exogenous) testosterone via TRT shuts-down the HPTA axis and prevents the testicles from secreting testosterone. This by proxy, stops the back flow and issues at prostate level. The exogenous TRT (and DHT) now become non-localised in the body and your prostate is not directly impacted.
Youâll notice in your initial in your initial labs, your progesterone was at the top-end of the scale which is indicative or your issues (this can also be related to having an overactive CNS and various other factors). Progesterone is important in males, but it also blocks DHT from working and results in symptoms identical to PFS.
My advice to you - consider TRT or as suggested above, DHT cream applied to the scrotum. I would opt for TRT, which I am currently doing and seeing improvement but still dialling in my treatment protocol.
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- How old were you when this happened?
- Did you have any lifestyle changes that you think could have brought this on (diet/overtraining, stress, steroid use, depression)?!
Did I mention that I can not feel my penis muscle? Its like it feels empty. Testicles do not feel stimulated. Almost as if they are not workingâŠ
Yep, had the exact same symptoms. That whole area feels âDeadâ and lifeless. Essentially the connection between your brain and your genitals has shutdown.
To be clear - my problem came from a testicular injury (due to sports) that caused a varicocele to form at the same time. With a matter of weeks, I turned into what was essentially a eunuch.
its almost as if you have hormones in your blood, but you have hormone slots which they have to fit into, but they are missing the target if that makes sense?
I had a total T level of 600 but had no libido and my Johnson wouldnât salute to any girl regardless of how good their pledge of allegiance was. I got on TRT after being told several times I wouldnât need it. I could now host rock climbing sessions on my dick. The only problem is itâs always hard so I need to look into polyamory. All kidding aside trt would likely fix a good bit of your problems. Youâre scared to try trt (and itâs understandable) but you have hit rock bottom and until you start making drastic decisions you arenât going to get drastic results. There are guys doing 1k cycles that come off and get back to normal so itâs not like trying trt is definitely something you have to stay on if it doesnât work. There are so many positives that come with trt that you arenât aware of until youâre on it. If I were you (and Iâve been at rock bottom looking for answers) Iâd try anything that looks like it could help. Youâve been dealing with this for 3 years now. Stop asking for answers and start doing something. It doesnât sound like things could get much worse than they are right now. (or try one of the other 17 suggestions just try something)
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okay guys so I visited my GP yesterday to show him the results of pelvic mri where it states that my prostate is âenlarged in inhomogenous signalâ He seemed tired of me and said that all of the tests I have done have come back normal with some slight abnormalities. He also said that he would not prescribe me anything for the enlarged prostate as many âOLDER MENâ have this and they do not complain of my symptoms.
He asked if I would consider his recommendation of seeing a sex therapist. This all feels like a sick joke to me⊠
What is a sex therapist gonna tell me? You have not had an erection in 3 years, and genital numbness? Try putting orange juice on your nuts and put it in an elephants ass and all your problems will resolve.
It is now clear to me that my only hope is by experimenting myself. Now I have been talking to another person I met on another forum, with the exact same symptoms as me. He claims that he also had DHT low and high , with no relief in symptoms, as well as low and high e2. His problems also began after paleo diet.
Now I was wondering if something like Clomid would maybe be a good thing to try first?
I donât understand why you are not seeing a doctor that specializes in the prostate. It doesnât seem your GP has any clue whatâs going on and is getting frustrated making you someone elses problem.
Its difficult to find a sick care doctor that truly cares, most are inadequate and simply do not care.
David pointed you in a direction I think you should investigate with the right kind of doctor.
thing is I have had about 3 or 4 prostate examinations since this all started⊠All 4 have said that my prostate was normal size, the bladder was clearly filled on ultrasound and also completely emptied after urination. But i still drip quit a bit after urination⊠One of the tests even showed my prostate volume, I remember googling it and it was like my prostate was way smaller then normal. Something like 10.79 cubed or something like that
"1. Initially when I started methylcobalamin (source naturals sublingual) I felt like my genital sensitivity was improving as well as my libido (which was practically nonexistent) After my initial detox reaction to the b12 went away and I could sleep again, all positive effects of the b12 on my sex life stopped.
2. My vitamin D was low and taking 50,000IU as prescribed began to help with erectile dysfunction and energy levels. Some help but nothing to write home about - still numb.
-At this point, with the methylation treatment, my sexual stamina was ok, but my libido was still crap, my sensation only mildly better.
3. Recently had a bad time sleeping and forgot that usually I take niacin when this happens (e.g. overmethylated) I went to the doctor and got ambien. While on ambien, I experienced some sharp pains when I urinated, but noticed that my reflexes down there (including perianal area) were strong againâŠI also peed with a lot more force and the stress urinary incontinence stopped! Then I remembered the niacin, and began taking that instead of the ambien, which wasnât helping my sleep but was giving me nightmares. The niacin continued the same thing with my urinary situation, I continued to get the sharp pains and more forcefully urinate and not get the dribbles so bad after urinating. Eventually, these results stopped once I was off the ambien altogether, however. I hypothesize that something GABAergic somehow acted on my motor neurons down there (perhaps onufâs nucleus but more on that later)"
I found that on someother website âŠthis guy also randomly got messed up at 24 years oldâŠ
I think our ultimate problem is leptin deficiency⊠We starved, leptin levels plummeted and slight weight gain afterwards is just not enough.
I upped my calories since my last post and I can safely say I sleep a little bit better, itâs harder down there and from a genital feeling perspective it went from 2% to 4%âŠ
Not amazing but itâs slightly better, if I was you I would try to eat twice my caloric maintenance (high carbs) daily for 2 weeks⊠Certainly worked for me the first time I did so and never had the courage to do it again. I canât guarantee you it will work but it worth tries, studies says such a regimen can increase leptin by 300%.
what is your biggest complaint/symptom?
a little update on some stuff I havenât metioned or have just noticedâŠ
-My testicles seem to me like they have shrunk. They are know about the size of grapes, before they were like a golf ball and half?
-I noticed I have no vascularity in my arms especially.
I have come to the point where I did not want to come too. After 2.5-3 years of suffering I realize I am not going to get any help from doctors. I really thought when all this started I would get a diagnosis in 2 minutes. I am so messed up that I am in shock that the doctors can not something wrong with my hormones. It looks exactly like post finasteride syndrome however I did not take the drug. Maybe some kind of Androgen resistance or something.
Finally I was wondering if anyone thinks I should try Clomid or whatever? If so how much should I take and how often? For how long?
Your testosterone levels are fine, itâs the low estrogen and DHT that may be causing problems. You need to consider TRT to increase both, but you will need higher levels than you are at currently.
Maybe TRT will allow you to sidestep whether is causing problems. Clomid isnât really a good long term option.
Have you considered going to a private specialist?
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its too bad I dont have blood tests with hormone values before this shit storm happened. I dont mean to sound like a parrot repeating the same things over and over again, but this is what I learned/know.
-My testosterone level is fine
-My E2 and DHT are low.
-e2 and dht are metabolites of T. Meaning If you have normal t you should have normal e2+ dht levels.
-I did not take a dht blocker or ai.
- liver enzymes are elevated, as well as dhea-s and billirubin. Prostate is enlarged.
-I do not feel like I have low testosterone. I FEEL LIKE I HAVE NO TESTOSTERONE
-I went through puberty and I played 2nd division soccer in europe at the youth levels. I know what hormones are and how they make you competetive, how you feel like you have juice and blood running through your muscles that make you squeeze your teeth and endure anything.
After using various forums on the internet and not getting much answers I was told by many to try Dr.John Crisler. I contacted him through facebook. He told me that my symptoms can be caused by low DHT. I got my dht levels checked the next day and he was right, they were low. I asked him for more information and he said that he would not give free medical advice for obvious reasons. He asked if I would like to become a patient of his but the price was out of question for my part of the world and current situation.
When I thought I would contact him again for a 1 hour consultation I found out that he had past away. I felt like he was my lifeline and it went away. Almost as if there is someone putting a curse on me with all this crap
There are other docs just as good. Keith Nichols is one for sure but Iâm not sure what he charges.
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Low estrogen should feel like you have no testosterone, low estrogen causes extreme fatigue.
I donât know much about hormones, but I always said that I feel like my issues have more to do with low e2 then with low dht. I have read about how low e2 makes you feel. Lack of penis sensitivity, dry tired eyes, dry penis glans, high scrotum, extreme fatigue, and even urinary symptoms. @systemlord I got fed up and even bought soy milk to try to raise it. After about 2 weeks of drinking it I decided to check blood again and my estrogen was even lower!
I found this about soy
" Early research raised concerns that phytoestrogens could raise estrogen levels in the body. However, they may have the opposite effect.
Phytoestrogens are weaker than estrogens that the body produces. When plant estrogens enter the bodyâs cells, they push out the bodyâs own estrogens."
I remember when on new protocols as my estrogen was rising I could feel warm tingling in my penis/testicles and scrotum area. DHT is needed for gentile sensitivity as well. Raising estrogen may not raise DHT, you still should consider TRT as a last resort.