There isn’t much info on this. Hoping to get some good answers from people with knowledge, and not people who have no clue and just want to answer.
MGF is a sort of derivative of IGF-1 that creates new satellite cells. Supposedly it and IGF-1 conflict with eachother, so if you run them exogenously, they are supposedly more effective when run separately. That said, steroid cycles usually boost IGF-1, either through a boost in hgh or at a muscular level (testosterone vs deca). With that being the case, would it be better to run MGF when cruising or between cycles instead of during a cycle/blast so that the extra IGF-1 didn’t interfere?
I’m going to run PEG-MGF and IGF-LR3 alternately for four weeks at a time. Obviously it’s okay to run IGF-LR3 during a cycle, since steroids stimulate an increase in this naturally, anyway. What I actually do is run it at from 30-100mcg daily and 2iu hgh daily. Anything above 6iu hgh gives me sides, but igf does not, and igf is what actually grows new muscle cells, not hgh. HGH just stimulates igf production at the liver. Why I still take hgh is because exogenous igf supplementation shuts down natural hgh production, which will cause lethargy, among other things. HGH, not igf-1, is primarily responsible for converting t4 to t3, and keeping you lean.
IGF supplementation is only good for maybe 4 weeks because receptors desensitize, and need a break. Alternative protocols to avoid this suggest supplementing alternate days, etc.
I also have some interesting side thoughts regarding this, hgh, cycle length, etc., which I may discuss later. …Or maybe I’ll just discuss them now, though I want to focus on the original question. Some guys say to just keep running gear/hgh long term, and increase doses when gains stall. I’ve never had good luck with that. My research tells me that androgen receptors have been proven to upregulate, so that isn’t the issue. IGF-1 receptors downregulate, particularly after four weeks of high exposure. That makes me wonder if IGF-1 receptors, which are involved with the development of new muscle cells, are the limiting factor. Furthermore, IGF-1 and MGF conflict with eachother, and MGF is necessary to create new muscle cells that IGF-1 later helps grow. This makes me wonder if IGF-1 receptors and IGF-MGF conflicts are the limiting factors in steroid cycles. Sure, a longer steroid cycle may grow existing muscle cells, but new muscle cell development will be curbed with a long steroid/hgh cycle due to high IGF-1 levels for extended periods. This may be why some have better luck with shorter cycles.