Just consider that when I used Anavar it was usually leading to a contest and I wanted to minimize water retention under my skin. I agree with @hankthetank89 that I would choose a different anabolic to build muscle if I could find one. But you might be stuck with what you have.
Because I felt through me experience that my androgen receptor site sensitivity began to drop after 8 weeks into a cycle (my strength gains would slow), I usually stopped the cycle. But for a contest I did 12 week cycles. So after 6 weeks I would change anabolics and increase the mg/wk by about 50%.
So in your case of a 16 week cycle, I would recommend increasing your total mg/wk after 8 weeks of your blast. If you don’t get diminishing gains over the cycle, it probably doesn’t matter. Just take the same mg/wk for the full 16 weeks.
Eq I would need to donate blood once or twice in the cycle correct? As well as is eq injected once or twice a week? I was thinking 300mg a week on eq since it’s my first time. As well as primo, what’s a good dosage to start for the first time and is that a everyday injection?
No, i dont get into all this blood donation thing. Do it if you want, but dont do it because some people just say so. All i got from dumping blood was crashed ferritin which made me feel like shit more than i would have ever felt on just thicker blood. Take some aspirin if thats a problem. Donating blood from time to time is healthy, i see it as an oil change and i do it myself, but dont JUST do it, because someone said to do it.
EQ has a long half life, you can probably inject it less often but i always do everything ED, as id rather use small needles and pin different spots with less oil volume than do these fucking 3cc shots that leave a lump for a week.
As far as dose goes, id say do 500 test, 500 eq… watch the e2 around week 5-6. If it comes down crashing, lower eq, if its still high, up it to like 800.
People take EQ anywhere from 500-1200.
You can also probably front load like a gram on day before the start and then just do what you would do normally the next day, if your goal is 500mgs a week.
You shouldn’t have any issue injecting long ester frequently. If you pin EOD with Test, just put the EQ in with the Test. Just don’t inject short esters infrequently.
I think this is actually pretty good advice. Asprin isn’t hard on the liver comparably to other pain meds, and should lower RBC.
I think Hank is right here with a caveat. You are monitoring and are comfortable with your blood pressure measurements. If you think your BP is too high, then you should try to figure out the root cause, which would be AAS use in this case, but you may be able to figure out which factor from AAS use is causing you the biggest increase in BP and address it. Is it bloat, high hematocrit / RBCs, being in terrible cardio condition, etc? Bloat would lead to diet changes or AI or both being employed, high hematocrit / RBCs you would figure out with blood work, and donate blood. Terrible cardio condition you would address by doing cardio. AAS can also just directly increase BP it seems (which you might use a BP med for, but cardio seems to help here too). You might find yourself doing a bit of each of these things to bring down BP. I would look to dumping blood last though.
You’re gonna get a giant range of answers that work for the guy who posts it.
Pick what works for you and run with it. If 250mg keeps enough muscle on but also allows your health to recover after the blast, do it up! Me, I’d run half that, but again, I’m not you
Aspirin works by blocking platelets from binding together. I’m not sure how it would impact blood thickening with higher hct, but it would certainly address any platelet issues. I typicall donate blood before my routine work. This time I did not, and there was only a 1pt increase in my hct. Just food for thought. I will donate again, but because I want to and not because hct.
I think @tareload posted bloods showing a drop in hematocrit using 325 mg a day. I think he also had a study (which I couldn’t find with a google search).
I did a trial of 325 mg/day of aspirin for the last 3 maybe 4 months for a number of reasons. I had also concurrently been slowly ratcheting up my TRT dose from 70 mg/week to 100 mg/week over the same time frame. Pulled blood work last week for a 6 month appt and was expecting to be back closer to 50% on Hct since I typically start to really make RBCs over 80 mg/week on my TRT dose. Last Hct measurement was December 2020, and I had stabilized Hct at 47% using modest 70-80 mg/week of TC. Over 100 mg/week of TC I can easily get up to 50% or over on Hct.
To my surprise my Hct came back at 44%. Not suggesting you take 325 (regular dose) mg/day of acetylsalicylic acid but it does appear to be a potent regulator of Haematopoiesis in the bone marrow. If you have issues with TRT induced erythrocytosis maybe this is a useful tool in the toolbelt? Downside for me was a lot of bruising but you are also getting benefit of clotting potential reduction via multiple mechanisms in addition to RBC/viscosity reduction. In case you’d like to read more:
A picture to show just how significant the aspirin result was. Peak was on a 100-125 mg/week TC protocol (some of the data points have some ND or oxandrolone thrown in). Dropping down to 70 mg/week put me back down to the 47-48 range. Aspirin plus 100 mg/week TC put me back down to 44-45 pre-TRT baseline. Hydration before testing about the same for all data points (I drink a lot of water and make sure I have to urinate pretty badly when I do the blood draw each time). I’d estimate a 5-7% reduction in Hct with 3 month use of aspirin. But I may be special case with heterozygous HH mutation.
To the reader, hope this helps and be careful with the potential GI concerns (as Nelson mentioned) and kidneys if yours are compromised.
Thanks. @tareload this is your personal experience from what I’m gathering? Interesting for sure. I dug a little deeper, but I’m sure there’s other digging that cold be done to disprove my thought. Aspirin can help by decreasing packed cell volume, ie decrease platelets, overall decrease in packed cell mass, thereby lowering total blood viscosity. For that to happen you’d have to stay on the aspirin, as it wouldn’t impact the erythrocytosis AAS causes? Unless you have a bleeding ulcer, in which you would be losing actual RBC volume which the aspirin may contribute to lol. Sorry, don’t want to derail the post.
Long story short, besides effect on platelets there are some mechanistic studies (shared above) that show direct effect of aspirin on Haematopoiesis in the bone marrow (at least in rodents). This was news to me and concurs with my anecdotal experience (above). Not many seem aware of this.
Aspirin and platelet effect (separate from the erythropoesis effect above):
Have you tried Nattokinase for high HCT? I just read about that and started taking some since my CBC runs high just on TRT. I also take usually take 325mg Asp per day along with Lisinopril for HCT
