What to Expect as You 'Come Up' on TRT?

Hi guys,

Started on TRT a little over a week ago (100mg scrotal cream daily).

  • Week 1 I was feeling great. Took a huge chunk out of my depression, exercising all the time
  • Week 2 Still exercising, but the anti-depressant effect went into hard reverse. Some pretty deep depression and my emotions were all over the shop. Two days later that’s cleared up

Is there a trajectory that this tends to follow as people ‘come up’, or is it all individual? No physical changes but probably too early to comment

Any guidance appreciated. It’s all new to me

No you’re coming down, when you first started the cream, you were stacking exogenous T on top of endogenous T, now your natural production is plummeting and is getting shut down.

Time will tell if you absorb enough of the cream to continue.

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No you’re coming down

That’s a really good point actually. I hadn’t considered that. When do you think we’ll hit the trough?

If you were on injections, I would say natural production gets close to being shut down around 3 weeks. I’m unsure about the creams, but I imagine it could take a little longer due to the up and down natural of creams.

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Spend an afternoon and read through the various new user posts. That’s my guidance. You will gain a lot of insight and answer a lot of your own questions. Then formulate any more open concerns with specific questions.

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