Very High Estradiol

Welcome back KSMan.

@PKNY I have no boners this week. Feeling pretty crappy, just took a third of the pill. Hopefully it will act quick…

Hey all, been a few weeks and wanted t give an update. Also had some symptoms, I am concerned about.

so, do prescribed Arimidex, i am taking .25mg e3d. The first week i took .25 EOD I started to feel better, bloat, muscle fatigue, and recovery, and sleep much better. I started to even get some wood back in the morn. But now, that seems to have gone away, still feel great, and no other noticeable symptoms. Any ideas? I plan to get blood tests very soon, to see if m going in the right direction.

I am taking test-cyp .50mg every Friday, Monday, and Arimidex, E3D.

Thanks all for your help, and support!

-Alex

You may be an over responder to adex,
cut back Adex to 25mg per week.
I know it’ll be hard because the pills are so small.

Space you cyp out a little better.
Take 50ml Monday and 50ml on thursday.
Take 12.5 Adex on M and Th as well.

Keep an eye out for aching joints, bad mood, low libido as they are symptoms
of crashed E2. When are you getting blood work again ?

Thanks PKNY!

I took my last .25mg adex on Saturday, ill wait to take it till next sat to see what happens. I plan to call the doc tomorrow morning, make an appt. asap!

Checking with bloodwork would be great.
I’m an over responder to Adex too, and I tried for almost a year to balance e2 with it.
I used the research chemical version (liquid) and as a little as 1 drop of it made me
feel like crap, two drops crashed me.

I wish I would have gotten bloodwork way back when, it would have saved me a lot
of time and needless suffering. I’ve used aromasin for the past few years and it’s much better.
No crashes, no issues, supposedly easier on the lipids too.

Not taking anything away from Adex, its inexpensive and effective for a lot of guys.
But if you over respond to it’ll hurt you more than help you.

@PKNY, whats your dosage on aromasin? Doc, could not find it in his book/computer. Does it go by another name? Do you need a script for it?

Thanks!

Aromasin is the brand name for Exemestane
It’s by RX, but I buy a generic brand from All Day Chemist.
If you google Aromasin, it will take you to the mfg site.

They come in 25mg tablets, but I take 6.25 (1/4 Pill) EOD.
It’s harder to crash e2 with aromasin, but if you do, you recover
faster as it has a shorter half life vs adex.

If you search aromasin on the T-Nation site you will find a lot of
conversation comparing and contrasting adex and aromasin.

Blood test on Thursday.

So, other than libido, I have had no other issues. In fact, at my crossfit class, today I seemed to have endless energy. Hope that continues! :slight_smile:

-Alex

Supplementing T stimulates bone marrow to produce more red blood cells,
It’s called Erythrocytosis. Having more red blood cells helps you carry extra oxygen to your
muscles…big advantage for endurance athletes. Your doc will (should) monitor that level though.
If that level (hematocrit) gets too high it makes it more difficult for blood to circulate and can
cause high BP and left unchecked, stroke.

Donating blood will keep that level in check, and you’ll be doing a good deed !

Ok, kinda concerned, have not taken and Adex this week, waiting for blood test, libido still no existent, notice face kinda breaking out with zits, but may be due t stress. Attitude and feeling kinda normal, no physical issues while working out. Blood tests tomorrow…

The acne thing is a weird one. I developed bacne after lowering my dose from 100mg/week to 60/week. Good luck with the labs.

Dropping Adex will put you back to your same high E2 symptoms.
Acne is a tell tale sign. The hell of is that taking Adex will crash your E2 and
keep you feeling like shit.

Any luck with your doc and Aromasin ?

So, are you saying that acne is a sign of high E2?

I have doc appt. today at 1:30

You are washing out and should resume at 1/4th the dose and see how that feels. In any case, do labs after you find something that feels decent so the labs have value. There is guidance in the stickies.

High E2 symptoms :
Acne
You will have some libido, but erection trouble
Trouble ejaculating
Anxiety
Bloating
Personally, I get moody and lose my temper fast…my wife says I’m “bitchy” when it happens
to me. lol.

As discussed above, you may still be able to use adex, but you would use 1/4 the dose as KSman suggests.

However, if your doc is willing to write a script for Aromasin, you should get it. No need to pay for another appointment
to get that drug should you need it.

Got blood drawn yesterday, didnt see the doc this time. Not what I had expected, oh well. Ill see what the labs say, and make another appt. I guess there was some miscommunication between the receptionist, and myself.

@PKNY, I think I have all those symptoms, wonder if I crashed my E2, by taking .25 EOD, and when I felt bad on 3rd day, stopped, took .50mg of test, as prescribed, of friday, and Monday, and then didnt take Adex, until yesterday, because I thought maybe I crashed my E2. Im kinda jacked up. Gonna just take it .25 once a week, for a while, see how that makes me feel.

Adex needs to be dosed more often than once per week based on it’s half life.
I know spacing .25 into three doses is hard. You can dissolve the .25 in a 1 ml of vodka.
Then take .33 of the vodka/adex combo EOD. Using a 1ml graduated eye dropper
makes the process easier. You can get them with a small bottle at most healthfood stores.

Crashed e2 symptoms (for reference)
Aching joints
ED that won’t really respond to V or Cialis
Lack of libido
Lack of energy
Depressive, hopeless feelings

So, I have typr 2 diabetes, have not had alchohol for 2 yrs, wondering if I can, there are a lot of conflicting opinions. So for the crashed E2, I have ED for sure, lack of libido, energy. is so, so, but thats why I thought about being low T in the first plce, so, i dont have anything to comapre to since at least 2 yrs. Not depressed, or hopless feeling. But have felt on edge, nervouse recently. its very hard to tell wether or not I am high E2 now, or low…

But it seemed to me, I had a spark with libido yestrerday morning, took .25 adex around noon, and seemed to have lost that spark. Took my normal test dose of .50mg on Friday, and .50mg on Sunday, .25 adex on Thursday.

Thanks all, this convo has kept me very optomistic! :slight_smile:

You can probably crush it up with water. Vodka seems to be the solvent of choice though.
Or you can google research chemicals with the word arimidex, and you can find the liquid
formulation on line without an RX.

It’s difficult to know high e2 vs low e2 as the symptoms are very close with each other.
The key difference ime is sad depressed feelings when too low accompanied by aching joints
knees and shoulders etc. Anger, short temper and bloating are the markers I notice most when too
high. ED and libido problems accompany both high and low.

I know KSman is a big proponent of Adex, as it’s cheap and works for a lot of guys.
But, I haven’t come across many threads where an over responder to it can successfully manage
e2 by cutting back to 1/4th the dose. I could be wrong, but I’ve yet to read one where that
strategy has been successful. It seems either adex works perfectly for you, or you over respond.

Aromasin made a huge difference for me, but since you don’t have it yet you should give the 1/4 dose adex
protocol a try.

Your welcome for the convo…this place is great for guys in our situation.
I know I learned a ton here, and had lots of support through tough times of my own.
Cheers !