Upcoming Interview with physiolojik

Describe your process of evaluating a new patient for trt and if appropriate how you layout a beginning protocol. What are you looking for with symptom resolution. Is there a point where you come to the conclusion that remaining symptoms are not related to lack of testosterone?

Thank you

Sweet I have a question I’ll post when I get back to Aus. On plane now

So, @dbossa… what gave you the idea to contact/get ahold of Dr Sir? His wealth of knowledge is impeccable

  1. How much do you expect cortisol to drop after starting TRT in patients with chronically high cortisol?

@unreal24278 he contacted me. He said he enjoyed the content I was providing here as well as on the YouTube channel and would enjoy being interviewed by me. Needless to say, it took me by surprise. We’ve been texting regularly ever since. Nice guy!

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Yea, he’s a cool guy… very busy though (as is to be expected from a man with 4 kids and a full time job as an endocrinologist whilst managing a clinic of his own!!!

I haven’t spoken to him in a while, but when I did he always gave me solid advice regarding questions I couldn’t ask anyone else. His presence will forever be missed by myself and many others.

He’s a grown ass man. If he wants to answer them he’s got them. Not asking a question is a great way to not get an answer. Post your question

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@wolf359 - he created a thread a while back related to your question -

Things We Do BEFORE Rx Testosterone

Yes, I know, but the interview is not necessarily a continuation of a forum thread. People watching/listening may be unaware of any postings here and would be interested in his processes and treating philosophy.

Very true @wolf359, I was just taking this into consideration when responding with that link.

@bcostigan41
That link is great. I had totally forgot about it

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I’m going to try and get to as many questions as I can during the interview.

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Hopefully this will be the most viewed video yet, there sure seems to be a ton of interest

A couple of questions:

  1. What compounds and doses are beneficial and deleterious to mental health? For example, I’ve seen research that 500 mg per week of testosterone is very effective as a treatment for depression.
  2. What doses do you start to see significant side effects? Some doctors seem concerned that anything over a TRT dose 200 mg will cause long term damage, whilst Dr Randall McClain says there’s evidence that 600 mg is safe.

Thanks!

Hey guys… the interview is confirmed for Saturday, January 11th at 1pm Eastern Standard Time on the TRT and Hormone Optimization YouTube channel.

We will do our absolute best to try to answer as many questions as possible. T-Nation guys will get priority over the chatbox guys.

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which timezone is that @dbossa?

Sorry about that… I just edited the post… Eastern Standard Time

  1. What FT/TT level do you recommend someone hit for a ā€œcycleā€? When people talk of cycles they always talk in mg/g which seems odd considering the subjectivity of it.

  2. What do you look at when your TRT patients complain of fatigue? If its DHEA or pregnenalone where do you like to see their levels?

My questions

20: regarding the whole andropause movement. Do you believe testosterone levels within the male population legitimately and consistently decline by 1-2% per year say after age 35… or is the new, alarmingly high prevalence of hypogonadism within older populations (and younger populations now) a result of poor lifestyle/dietary habits, extensive exposure to environmental toxins/chemicals (preservatives from processed foods, phytoestrogens etc) and overuse of various prescription meds (SSRI’s, Statins etc)… also, why are reference ranges getting lower and lower, I keep seeing ref ranges now that are teetering on 75-600ng/dl… no normal adult male will have a TT of 75ng/dl

21: PFS… what do you do about the men unfortunate enough to have acquired hypogonadism and/or neurological abnormalities stemming from use of 5a reductase inhibitors… it’s not merely the test levels, but the potent effects blocking DHT can have on downstream hormonal patterns (of which many DHT metabolites are vitally important regarding neurological regulation as they function as potent neurosteroids)… if these pathways are perhaps irreparably damaged, are these people simply doomed to live out a life of erectile dysfunction, depression and overall inadequacy?

22: With TRT becoming more and more mainstream, yet still not entirely understood by many MD’s, it appears quite a few men with very unhealthy lifestyle habits are being put on. An extreme example would say be… a morbidly obese man (BMI of 40, bf% 40%)… I’m tempted to say bmi of 50 but at this point it’s just a joke lol… he also has type 2 diabeties and is a smoker. A practitioner puts him on TRT (innapropriately, he clearly needs to clean up his habits)… what impact would a mere replacement dose have on this mans long term cardiovascular risk factors. Many say ā€œTRT doesn’t increase overall cardiovascular mortality rates etcā€ā€¦ but for someone in this state, what would the long term implication be? There’s a reason his T is low, aside from insulin resistance/leptin resistance, a super shitty lipid profile (I assume), perhaps hypertension, his adrenals are probably jacked up from the smoking and the obesity etc… his T is low in part due to many mechanisms within his body being thrown off due to… well his terrible state

@dbossa
@physioLojik

My questions are very long, I’ll shorten them up when I get home

My next question would be ā€œwhat do you think he future of TRT/ART holdsā€ā€¦ but I’m pretty sure I know the answer. I hypothesise it’ll be some kind of SARM/uniquely modified AAS that legitimately entails minimal long term risk/effect on numerous haematological, endocrine, neurological, cardiovascular parameters to accost for the variables detailed in question 22… and whoever creates this drug will be rich as FUCK… because he/she may single handedly dramatically reduce rates of obesity/Ill health, be able to improve survival rates within individuals in severely chachetic states (say people on chemotherapy etc) and whatnot… I hope it’s me… However I don’t need think I’d be cold hearted enough to put a patent on such a compound if it were that successful, generics are more affordable

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So glad I didnt have students like you when I was a TA. :joy:

Most 18 year olds would ask ā€œwhat’s a good stack for me to gain 50 pounds and make my dick huge at the same time?ā€

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What’s TA?

And… what stack can I use to gain fifty FIVE pounds and get my dick huge?

I was thinking

1500mg tren
100mg test
50mg sdrol daily
10ius of GH daily
40mcg clen 2x daily

#suddencardiacdeathatage22

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