[quote]happydog48 wrote:
Primary hypogonadism is when the testes themselves aren’t functioning. Secondary hypogonadism is when the testes work fine but the hypothalamus and the pituitary aren’t sending out the signals for the testes to produce testosterone. The shorthand way to think of it is primary = production and secondary = control.
In the case of bodybuilders with a normally functioning HPTA, the high levels of testosterone caused by the exogenous testosterone they take, cause the hypothalamus and pituitary to stop sending signals to the testes because they sense that no testosterone is needed. The testes shut down because the hypothalamus and pituitary are functioning correctly and stop making LH and FSH. This is why hCG is effective (in “control” cases), because it simulates the signals from the H/P and the normal testes react as they should and produce hormones.
In the case of LastIDnotworking, if he took hCG and it elevated his T levels, he would know that his hypogonadism was secondary. If the hCG didn’t raise his T levels, he would know his hypogonadism was primary.
Some doctors will tell you that if your testicles are not atrophied at all, then you have primary hypogonadism. They’re trying to function, they just aren’t getting the job done. If the problem is secondary hypogonadism, then the testicles will atrophy just as happens to those whose exogenous testosterone has caused the HPTA to shut down.
Personally, I’m not so sure it is that simple. I believe low T it is spectrum with primary and secondary at opposite ends and we may be anywhere along that line. In other words, I believe it is possible for your “set points” to deteriorate or get screwed up so that your HPTA is actually working correctly, it is just working to maintain levels that are messed up. And along with that, you may or may not have testes that are trying but not succeeding to produce testosterone.
I’ve actually come to believe that all of this really matters very little. It is good to have a knowledge base, but the bottom line is what are you going to do?
So LastIDnotworking, my question to you is, what are you going to do? What do you want to have happen? Do you want a doctor to treat you or are you going to treat yourself? What difference would it make to you to know if your hypogonadism is primary or secondary? If you’re looking for knowledge about the functioning of the HPTA, that information is readily available to anyone who simply looks for it.
Have you discussed your blood work with your doctor? What was his/her reaction? Have you discussed your symptoms with your doctor? Did you have your thyroid levels checked?
You post raises a lot of questions and it would be foolish to recommend a course of action given so little to go on.
Having hormone issues isn’t like having a headache and trying to decide if you should take aspirin or tylenol. It’s a big deal and not something to decide from a couple of posts in a forum.[/quote]
Great Explanation! happydog48
Let me just say it is very important to find a good doctor also. One that knows HRT and 1 that is willing to treat you. Sometimes it’s hard to find or not feasible to get 1 of these doctors, but it does make all the difference in the world. Like happydog48 said It’s a big deal. Good Luck