TRT: Most Probable Weekly Dose Range for Treating Male Hypogonadism

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What is TRT and What is NOT TRT

Just wanted to clarify…7 mg/day of testosterone is 49 mg/week of testosterone which would be equivalent to ~70 mg/week of testosterone cypionate. Testosterone enanthate MW is 400.603 g/mol so 49 mg/week of testosterone would be ~68 mg/week of testosterone enanthate. They are pretty close. To your point, 70-100 mg/week of testosterone ester would be generously equivalent to what top-quartile eugonadal healthy male is producing endogenously. And guess what? When you go to the trouble on pu…

What is TRT and What is NOT TRT

And even more data from Bhasin’s work in the 2000s: [image] [image] The ordinate (y-axis) is mean (AUC/delta t) TT level which I calculated as ~1.6*TT(trough) from the papers. Understanding serum mean TT level (mean calculated as AUC/delta t) allows one to very quickly conclude 200 mg/week TC dosage (or even 150 mg/week) brings an older guy way above reference range. Feel free to take over to Facebook groups to help educate.