TRT for 10 Months, No Sex Drive

Post Edited to show proper information:
-28 yrs. old

-5’ 10"

-34" empty stomach

-192 empty stomach (currently in calorie restriction)

-Body hair came in later than most. Couldn’t grow a real beard if I tried and only lately (perhaps results of my new higher test levels) has it been coming in at a more rapid pace.

  • Lately I feel like I’ve been carrying more body fat, and as usual, the majority is between my neck and hips. Today, I went and got a DXA scan just to see where I stand. Not good. But, as you can see, lower percentages in the arms and legs and a fat boy in the middle. I’ll include pictures and an image of the scan results.

-HISTORY: About four years ago, I felt like shit. Depressed, no sex drive, no desire to be social. I got blood work and the doctor told me I had low testosterone. I can’t remember the units but I know I was at 179 on a scale of 250-1100. He was not a specialist and was uncomfortable just writing a prescription for therapy because based on a physical, everything seemed to be working “down there.” Fast forward 6 weeks to when I was finally able to see an endocrinologist and get more blood work. This time my levels came back at 581 on the same scale. Even though I was 24 and below average, she advised that I needed no therapy since I was in range. So I went on about my life.

About a year ago, I was happily engaged (married now) and had a lot going for me in life, yet I once again had a low sex drive and wasn’t really happy. I finally found a doctor that seemed to know what he was talking about. I took him the results I got from a generic clinic and he agreed there was an issue. He started me on Clomid and hcg and ordered more tests to see what other issues there might be. First blood test showed me once again with low testosterone. In June of 2012, at 27 years old, I started taking 100mg Test Cypionate once a week and Clomid every other day. I have gotten blood work every 8-12 weeks since and my test levels actually got up to 1467, albeit with high Estrogen levels. The doctor switched me from Clomid to Arimedex and the levels dropped. My IFG-1 levels were low so he threw out the idea of getting on CJC-1295 and I have been doing that for 8 weeks. Well, one would think that I was well on my way to feeling like a million bucks; however, that is not the case. I have had a minimal sex drive this entire time (side note: I can perform, but the desire is a rare occasion.) and I still have low energy - even when my levels were about the normal range. I’ve decided that I cannot afford to continue this therapy considering it’s not making me feel better.

TSH 1.48 (0.40-4.50 mIU/L)
T4, Free 1.4 (0.8-1.8 ng/dL)
T3, Free 3.4 (2.3-4.2 pg/mL)
Thyroglobulin Antibodies <20 (<20 IU/mL)
Thyroid Peroxidase Antibodies <10 (<35 IU/mL)
SHBG 49 (10-50 nmol/L)
rT3 19 (9-28 ng/dL)
Estrogen, Total, Serum 180 (<130 pg/mL)
IGF I, LC/MS 99 (63-373 ng/mL)
Z Score -1.1 (-2.0 to 2.0 SD)
DHEA Sulfate 484 (110-510 mcg/dL) - I supplement with 50mg/day to reach this.
Testosterone, Total, Males 1436 (241-827 ng/dL)

-I’ve since learned that my initial realization of low T could have been caused by my diet at the time. I came off the diet, started eating whatever I wanted and my levels went up a bit. I have always been active; however, I have always been an eater. I was always soft growing up and I would easily classify any kid like myself as a candidate for low T. Was my low T influencing how I grew up or was how I grew up the reason I now have these issues?

I still love to eat and struggle with rejecting bad foods. However, with a specific goal in mind, one with a termination date, I am lights out with a diet. This has resulted in yearly variations in my weight. Up to 210, down to 190 and so forth. Typically, I eat very well during the working hours, moderately for dinner and whatever I want on the weekends.

-I am a program hopper. I would credit some of this to being injury prone and some of it to my hormones. Much like my sex drive and general feeling, my motivation to train varies. I will often change programs (Usually after completion of another) just to keep myself interested. I like training heavy, with low reps and usually lift 3-4 days/week. I would be very surprised if I was classified as overtraining.

-I have never had any unusual feelings in my testes. Note that when my doctor put me on hcg, he told me I would likely feel them “working” and I felt nothing.

-Morning erections are rare. Oddly enough, several times in the last year, I have woken up in mid-sleep severely aroused and would already be having sex by the time I realized what was going on.

I believe that’s it for now and will update with anything I can think of.

I’m now 5 days from my 1-year anniversary and everything is great, except my sex drive. No man should be living like this - I have got to get these issues figured out. I would appreciate any helpful advice that you guys can throw my way.

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I have all of the blood work results if you guys have specific questions…

Read advice for new guys sticky

You can edit your original post on the bottom right and add all info per the advice for new guys sticky.

If your chief complaint is low libido, it could be low DHT. Although this is not normally advised here, switching to a topical testosterone (androgel, fortesta, compounded cream) would increase your DHT levels via 5-AR in the skin. There is a strong correlation between libido and DHT.

If you can’t get your doctor to order the test, you can did it on your own:

[quote]iw84aces wrote:
Read advice for new guys sticky[/quote]

Thanks for that - been a long time since I’ve been on here. I’ll work my way through it all.

New info posted.

[quote]Kaynon311 wrote:
You can edit your original post on the bottom right and add all info per the advice for new guys sticky.

If your chief complaint is low libido, it could be low DHT. Although this is not normally advised here, switching to a topical testosterone (androgel, fortesta, compounded cream) would increase your DHT levels via 5-AR in the skin. There is a strong correlation between libido and DHT.

If you can’t get your doctor to order the test, you can did it on your own:

New info posted. Thanks for the guidance.
I guess it sounds like my biggest complaint is libido, but it is clear that there are bigger issues. I’m hoping to get everything working properly.

You need estradiol (E2) checked per the newbie sticky. Review that, fix your AI levels. If that doesn’t work deep dive some more.

Your DHEA-S is great. Your T may actually be TOO high for long term use. I would start with E2 tho

Not everyone is a horn dog. You said with high T, normal estradiol levels (after the AI) and Clomid you still had very little desire…perhaps you just aren’t a sexual person. Same with people with hypothyroidism, they think after getting their thyroid normalized they will be happier, but in the end, it may not have been the thyroid CAUSING mood dysfunction.

Lol ^^^ this is bullshit… don’t lose faith

[quote]iw84aces wrote:
Lol ^^^ this is bullshit… don’t lose faith[/quote]

Can’t say it never crossed my mind, though. When I first went in years ago, between my test and my getting results, I started thinking, “shit, what if he says nothing’s wrong and I am just depressed…”

I can safely say that I’m a very positive person and “not sexual” is the last way I would describe myself. Things just aren’t the way they used to be.

[quote]jholla10 wrote:

[quote]iw84aces wrote:
Lol ^^^ this is bullshit… don’t lose faith[/quote]

Can’t say it never crossed my mind, though. When I first went in years ago, between my test and my getting results, I started thinking, “shit, what if he says nothing’s wrong and I am just depressed…”

I can safely say that I’m a very positive person and “not sexual” is the last way I would describe myself. Things just aren’t the way they used to be.[/quote]

Other problems like aging and neurotransmitter problems can cause this.

Your SBGH is high.

Really need to check E2 and free T. DHT and prolactin as well.

High SBGH can be caused by high E2 or liver problems. Do you have liver marker data?

You are GH deficient and this can contribute to your symptoms.

Your T is too high. That can cause sex problems. (You only need to be above 400-450 to have good libido, studies prove that higher than that does not increase libido more.) It is better to lower your T dose to get to a more reasonable level. That will also reduce your elevated E2 and thereby help libido. If you can reduce E2 enough by just lowering T and cutting out the DHEA (which raises E2) even the better, since arimidex itself can cause low libido irrespective of E2 levels.

Despite my DHEA levels being low (< 100), DHEA pills or transdermals take away my sex drive completely.

There are threads on another forum in which I participate in which a number of people complain about GH secretagogues killing sex drive, so the CJC-whatever you take could also be a culprit.

It’s a bad idea to start changing several things at the same time (like you are doing with T, E2, DHEA, and GH). They all affect symptoms and you can never tell which one is responsible so it is impossible to tune them all at once. If I were you, I would cut out the DHEA and the CJC reduce the T dose enough to get E2 in range without arimidex, and then let things stabilize.

Important: Even when you get the numbers right, it can take up to a couple of months for sex drive to return, so be patient and don’t keep on changing things based on how you feel that week.

Finally, are you seeing a legitimate doctor? The CJC he gave you is not an approved drug for human use in the U.S. He could (and probably should) be arrested for that. Also, combining Clomid with testosterone, as he did at first, is an unusual practice. It all sounds pretty shady to me. I would look for someone else.

Do you watch internet pornography?

[quote]jholla10 wrote:

[quote]iw84aces wrote:
Lol ^^^ this is bullshit… don’t lose faith[/quote]

Can’t say it never crossed my mind, though. When I first went in years ago, between my test and my getting results, I started thinking, “shit, what if he says nothing’s wrong and I am just depressed…”

I can safely say that I’m a very positive person and “not sexual” is the last way I would describe myself. Things just aren’t the way they used to be.[/quote]

So you used to be very sexual? When did you notice that it all changed? Maybe you are dopamine deficient and taking Selegeline or a dopamine agonist will help you more than continually tinkering with sex hormones. If you had high/normal testosterone, normal estradiol and everything else looks fine and you still had very little sexual desire then it may be something else

I appreciate all of the advice so far. As far as T goes, I’m only taking 100mg once a week so it is very surprising that my levels did get that high. They were around 900 before and at 500 the next time. I don’t know how much that varies depending upon when I last time I took my shot so take it for what’s worth.

As far as the doc goes, he is actually a well-respected doctor. However, I have noticed lately that he has loaded up on clients and now I don’t believe he is focusing enough on each one. I do plan on finding another one because this just isn’t working. In his defense, he didn’t put me on all of this at once. T and clomid, then fixed low DHEA levels by supplementation, then switched from clomid to Arimidex then added CJC.

[quote]Receptor wrote:

[quote]jholla10 wrote:

[quote]iw84aces wrote:
Lol ^^^ this is bullshit… don’t lose faith[/quote]

Can’t say it never crossed my mind, though. When I first went in years ago, between my test and my getting results, I started thinking, “shit, what if he says nothing’s wrong and I am just depressed…”

I can safely say that I’m a very positive person and “not sexual” is the last way I would describe myself. Things just aren’t the way they used to be.[/quote]

So you used to be very sexual? When did you notice that it all changed? Maybe you are dopamine deficient and taking Selegeline or a dopamine agonist will help you more than continually tinkering with sex hormones. If you had high/normal testosterone, normal estradiol and everything else looks fine and you still had very little sexual desire then it may be something else…[/quote]

Yes, very sexual. It all changed the winter of '09. I can’t find my original results from when I felt like shit the first time (I’ll see what I can find) but here are the results from my 2nd visit about 6 weeks later. This is prior to any manipulation of hormones:

5/4/2010
TSH, 3rd Gen 1.64 mIU/L (0.4-4.50)
T3, Total 85 ng/dL (76-181)
Thyroid Peroxidase Antibodies <10 IU/mL (<35)
IGF-1 272 ng/mL (126-382)
FSH 3.3 mIU/mL (1.6-8.0)
LH 4.4 mIU/mL (1.5-9.3)
Prolactin 5.8 ng/mL (2.0-18.0)
Estradiol 25 pg/mL (13-54)
Cortisol, A.M. 22.5 mcg/dL (4.0-22.0)
Total Test 571 ng/dL (250-1100)
Free Test 194.7 pg/mL (35-155)

The doctor looked at these and said nothing was wrong so I went about my life and then felt bad again 2 years later. I’m working on gathering all of the results over the years.

So, clearly there are a few other tests that I need to run. Is there really any point in doing them right now or should I wait until I’m off of the test, anti-E, CJC and Arimidex?

[quote]jholla10 wrote:

[quote]Receptor wrote:

[quote]jholla10 wrote:

[quote]iw84aces wrote:
Lol ^^^ this is bullshit… don’t lose faith[/quote]

Can’t say it never crossed my mind, though. When I first went in years ago, between my test and my getting results, I started thinking, “shit, what if he says nothing’s wrong and I am just depressed…”

I can safely say that I’m a very positive person and “not sexual” is the last way I would describe myself. Things just aren’t the way they used to be.[/quote]

So you used to be very sexual? When did you notice that it all changed? Maybe you are dopamine deficient and taking Selegeline or a dopamine agonist will help you more than continually tinkering with sex hormones. If you had high/normal testosterone, normal estradiol and everything else looks fine and you still had very little sexual desire then it may be something else…[/quote]

Yes, very sexual. It all changed the winter of '09. I can’t find my original results from when I felt like shit the first time (I’ll see what I can find) but here are the results from my 2nd visit about 6 weeks later. This is prior to any manipulation of hormones:

5/4/2010
TSH, 3rd Gen 1.64 mIU/L (0.4-4.50)
T3, Total 85 ng/dL (76-181)
Thyroid Peroxidase Antibodies <10 IU/mL (<35)
IGF-1 272 ng/mL (126-382)
FSH 3.3 mIU/mL (1.6-8.0)
LH 4.4 mIU/mL (1.5-9.3)
Prolactin 5.8 ng/mL (2.0-18.0)
Estradiol 25 pg/mL (13-54)
Cortisol, A.M. 22.5 mcg/dL (4.0-22.0)
Total Test 571 ng/dL (250-1100)
Free Test 194.7 pg/mL (35-155)

The doctor looked at these and said nothing was wrong so I went about my life and then felt bad again 2 years later. I’m working on gathering all of the results over the years.

[/quote]

Well that test actually looks pretty good…you actually have high free T! Your cortisol is a little high, perhaps due to any stress or an unhealthy life style but your doctor was right to not do anything about your hormones and I am not surprised, if these are your original stats, that you don’t feel much different after manipulation of hormones since this probably wasn’t the cause…

Per the Thyroid Basics sticky, I went and purchased a thermometer. The past 2 days have registered at 96.5 and 95.7. I took several readings and those were the average each day. I’m headed to the store to buy an iodine supplement in just a bit. I’ve called ahead; they don’t carry Iodoral, but the kind they have is 12.5mg so I’m sure it’s very similar.