TRT Blood Tests OPINION ASKED

Pharma / TRT
1

Hello to all.

DATA:

  • Male
  • 44 years old
  • 102 Kg (225 pounds)
  • Training 5 days a week at gym + 2 days playing senior rugby

I would like to have your opinion on my blood tests during my TRT (The test results are in Spanish, so I appeal to your kind understanding) . I started with TESTOVIRON DEPOT in 2021 with a dosis of 1ml (1 injection) every 21 days because I was diagnosed with andropause. [

TESTOVIRON DEPOT 250 250 mg/1 ml

](https://www.vademecum.es/argentina/medicamento/1443941/testoviron+depot+250+250+mg%2F1+ml+sol.+iny.)

During almost 2 years of doing that dose every 21 days, I really never felt any significant changes like strength increase or libido or anything.

In February 2023 I started a new approach with a TRT of 0.5ml every 5 days. After almost 2 month I saw huge changes on strength, mood, performance and libido. I ran a complete test (you can see below as INITIAL TEST AFTER STARTING TRT), and we changed dosis for 1ml every 7 days. With same results: feeling great and good strength. I also passed from 96kg to 102-105 kg of weight very lean and with the lowest percentage of body fat that I can remember having.

The situation is that I have also attached 2 exams that I took later. The first is from June 7, where you can see that the hematocrit levels are very high and the estradiol levels are also very high. I had told my doctor that I had been feeling that when I went to the gym and worked hard my head began to ache and my doctor, seeing the hematocrits and the issue of the headache, recommended that I donate blood to lower the hematocrit, which I did (you can see the result in the second exam on June 28). We also changed the periodicity of the injections and went to 21 days between one and the other, which I would be doing now.

I consulted with my doctor what he recommended for me to lower estradiol and maintain high testosterone levels, without harming my health, and he told me to try another month with this dose (1 injection every 21 days) and do tests again. If ESTRADIOL continues to be elevated, we will not do a T injection, but I will take pills to lower estradiol levels for 40 days (I think they are aromatase inhibitors, I donā€™t know).

I wanted to donate blood to lower hematocrit levels, but the legislation in my country (Argentina) only allows blood to be donated every 6 months, which makes it a bit difficult for me because I will have to see how to do so that they accept the donation. Perhaps you know how to help lower hematocrits apart from donating blood and I thank you in advance for your collaboration.

More than anything, I would like to know your opinion about these tests, the dose that I have been doing and if you have additional recommendations that you can give me to stay healthy without unnecessary health risks.

INITIAL TEST AFTER STARTING TRT

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JUNE 7th 2023

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JUNE 28th 2023

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1 Like
2

So what was wrong with this?

Doing good so Doc says what the hell letā€™s jack up the weekly dose 50%?

I would shoot for 100 or 125 mg/week and reassess symptoms and blood work in 12 weeks. 70 to 100 mg per week is reasonable for most (once or twice a week injections). You gotta find the ceiling where your RBCs dont get out of control.

250 mg every 21 days? NO.

250 mg per week? NO.

Are you fat?

I would find reasonable dosing to avoid erythrocytosis and AI use.

If you dont want TRT and more muscle then you get into polypharmacy, blast and cruise ā€œTRTā€, and things can get messier.

1 Like
3

Hi @readalot and thanks for your quick reply. On the initial dosis 250mg every 21 days, I really didnā€™t feel anything. So I talked with my doc and told him I was thinking of doing 250mg every 10 days and he said ok. One of my friend he is also in TRT told me to split it into 125mg every 5 days. And thatā€™s how I saw very good changes. Then I ran the tests and we decided to do 250mg every 7 days just because it was easier to to the injection once every week rather than doing every 5 days.

The ā€œproblemsā€ are the estradiol and the hematocrits as my doc mentioned. So thatā€™s why he suggested me to go back to a 21 days between every dosis (250 mg) and check if estradiol lowers (which it has as you can see from the test results. But still are high for what i would like it to be) and hematocrits also are lower but closer to risk levels (and I want to lower it too).

What do you suggest then? Thanks!

1 Like
4

Why increase your weekly dose by 43% when you were doing well?

See above. 100 or 125 mg/week. You dont need to inject whole vial at one time.

100 mg = 0.4 ml with your vial (250 mg/ml).

5

Just because it was ā€œeasierā€ to do the whole dosis. But yes, you are right: it was going fine, so better to keep it.

1 Like
6

Injections every 21 days is stupid given the half-life of these relatively short acting esters, because by day 10-12, levels are outside the therapeutic ranges leaving you hypogonadal 50% of the time.

This might work for an outlier, but the vast majority of men will not respond to therapy.

Men on TRT will typically have higher estrogen when aiming for high testosterone, as long as itā€™s within reason, this is perfectly fine if youā€™re not symptomatic.

7

Nooooooo!

Hang in there Brother.

100 mg/week:
Inject 0.4 ml per week for two weeks then 0.2 ml from vial the third week. Get new vial and inject another 0.2 ml that week. Now the second vial contains 2 more weekly doses.

125 mg/week:
If that is not enough you can do 0.5 ml every week (each vial will last 2 weeks).

Give it 12 weeks and assess symptoms and lab work.

8

Thanks @systemlord! What would be the symptoms to consider? And what about the hematocrits?

Thanks you

9

Yes @readalot I belive going back to 0.5 every 7 days itā€™ll be better. Thanks! Just want to know how to lower hematocrits and also if I have to check or be aware of another things or symptoms.

Thank you!

1 Like
10

In 12 weeks the Hct and estradiol will be back down. RBC lifetime about 100 days.

Less is more.

11

Guessing you get vials like I do of 250mg.

I bought medical 10g vials and put the months supply into one. That way its easier to manage without having open vials around. Can buy them on Amazon for dirt cheap.

12

Crying excessively during sad movies, low libido and erectile problems.

I believe the jury is still out on TRT induced erythrocytosis. A recent placebo controlled trial recently came out and did show a low number of pulmonary embolismā€˜s and A fib in the TRT group with high risk, cardiovascular disease, heart disease.

My problem is the levels achieved throughout the trial was between 300-400, sissy levels.

Testosterone is a vasodilator, it widens the blood vessels, so sissy levels you donā€™t get an optimum affect.

13

Thanks @systemlord

I want to do things the best way I can. Here in Argentina there not good doctors for TRT (at least I donā€™t know of anyone) and every time you talk about it they ask you ā€œwhat for do you want to do that? Just because of physique?ā€ NO!. Iā€™m not only doing because of esthetics (of course itā€™s a part of it), but because and mainly it makes you feel generally good (energy, strength, etc). So the question to me is WHY NOT DOING IT IF ITā€™LL MAKE YOU FEEL PLENTY AND GREAT (doing it under a profesional supervision well).

Once again, thanks