Total T is 580 on 100mg

On 100mg per week my total T is 580 - labs taken 4 days after injection - E2 is 20 . I feel pretty good . Should I up my dose to 150mg per week ( 2x per week 75mg ) . I lift weights hard and do cardio regularly . I have been loosing fat and my muscle is steady gains .

Nope. That’s upper-middle of (most) range, so your peak number is likely close to the “upper” limit. I wouldn’t go up. No benefit.

The issue here is that we do not know what the peak is; and frankly, we should not have to worry about such issues if you injected more often. Then the labs represent something else other than a snap shot of a dynamic situation.

Can’t refer to your body weight, yet another isolated post. In the past I have suggested 100mg T eth/cyp per 160 pounds for a guy that is lean. So one can do some weight adjustment for initial dosing. After that, one adjusts dose by lab results, but injecting once a week takes all precision out of the equation.

I agree, your TT seems a bit low. With someone injecting more often, if TT=900 was the target, the new dose would be 100mg x 900/580.

Note that one should not do this if HTC is becoming a problem, cannot see your labs ;(

If you increase T, E2 will increase and if you had E2 balanced, you would increase AI by the same factor. But AI:T balance is never right with injections done once a week.

I inject 2x weekly

I weigh in the 160-170 lb range, and I nearly shat myself when I was originally prescribed 200mg/wk cypionate. I asked if that was a high amount, and was told that’s normal for men. Well you know what? I’m starting to believe it was way too much for me.