Timing Coffee for Bronchodilator Effect

There is plenty of info on the Internet about the fact coffee dilates the bronchi. May not be the greatest thing for the job, but it can result in some effect

I want to take advantage of such for my physical activities, taking coffee beforehand.

But what I can not find anywhere is how much time in advance, one has to take coffee to act like this on the lungs. Can somebody help here?

A quick google search says:

Clinical studies have shown that caffeine is a weak bronchodilator, improving lung function for two to four hours after it is consumed.

What I want to know is how much time it takes to start the effect.

The timeline picture illustrates better:

image

What I want to know is how much time is the period in orange, concretely between taking the coffee and when it begins to make effect. And I don’t nor I will believe it is zero.

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Bruh

IDK how much more clear you want this to be. I literally google searched your answer for you, provided an article, and also quoted the specific excerpt you needed for your answer. lordt.

Sip coffee for 2 hours, then you’ll have a nice 4 hour window after those 2 hours.

For more bronchodilation, smoke some cannabis for 2 hours with the coffee.

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Again. You are assuming only one source as if it was a fact.
Even if it turns to be true, for me, what they are telling there, is the sum of the orange + green periods.
What I want to know, as I told you, is just the orange period. And I do not believe it is zero.

A man of detail. I like it.

ABSORPTION, DISTRIBUTION, AND METABOLISM

Caffeine is rapidly and completely absorbed in humans, with 99 percent being absorbed within 45 minutes of ingestion (Bonati et al., 1982; Liguori et al., 1997). When it is consumed in beverages (most commonly coffee, tea, or soft drinks) caffeine is absorbed rapidly from the gastrointestinal tract and distributed throughout body water. More rapid absorption can be achieved by chewing caffeine-containing gum or other preparations that allow absorption through the oral mucosa.

Peak plasma concentrations occur between 15 and 120 minutes after oral ingestion. This wide variation in time may be due to variation in gastric emptying time and the presence of other dietary constituents, such as fiber (Arnaud, 1987). Once caffeine is absorbed, there appears to be no hepatic first-pass effect (i.e., the liver does not appear to remove caffeine as it passes from the gut to the general circulation), as evidenced by the similarity in plasma concentration curves that follow its administration by either the oral or the intravenous route (Arnaud, 1993). Caffeine binds reversibly to plasma proteins, and protein-bound caffeine accounts for about 10 to 30 percent of the total plasma pool. The distribution volume within the body is 0.7 L/kg, a value suggesting that it is hydrophilic and distributes freely into the intracellular tissue water (Arnaud, 1987, 1993). However, caffeine is also sufficiently lipophilic to pass through all biological membranes and readily crosses the blood-brain barrier. Its elimination is by first-order kinetics and is adequately described by a one-compartment open model system (Bonati et al., 1982). In a study of adult men, a dose of 4 mg/kg (280 mg/70 kg human, or about 2–3 cups of coffee) had a caffeine half-life of 2.5–4.5 hours, and was not affected by age (Arnaud, 1988).

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Coffee enema anyone?

Does not appear to be a tangible benefit.

image

5. Conclusions

When comparable content of caffeine was administered, the and AUC of caffeine obtained from the coffee enema were about 3.5 times significantly less than those of the coffee consumed orally, despite having slightly but statistically faster . In addition, a single administration of the coffee enema or the oral coffee consumption did not adversely affect systolic and diastolic blood pressure and heart rate.

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Good luck with being spoon fed information, tried to be nice and help but was told the help I was giving wasn’t good enough :man_shrugging:

^There you go, you can just shove it up your ass =)

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Welcome to the wonderful world of forums where there are a distribution of fun people.

Next time ask for the induction period/absorption time before onset of action.

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Nice figure btw. Thanks for putting that together.

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https://journal.chestnet.org/article/S0012-3692(16)61876-7/fulltext

Although caffeine is a universal drug and has multiple pharmacologic and physiologic actions in man, there are surprisingly few objective data about its effect on pulmonary function. We conducted a short-term, double-blind, randomized crossover study in nine asthmatic adults who ingested decaffeinated coffee containing varying amounts of added caffeine (mean of 0.2, 2.5, 5.6, and 7.2 mg/kg of body weight) on different days. The subjects also ingested decaffeinated coffee and aminophylline (200 mg) on a separate day of study. Baseline and post-drug determinations of serum levels of caffeine and theophylline, forced expired volume and flow, specific airway conductance (Gaw/Vl), vital signs, and reported symptoms were obtained. Peak increases in serum caffeine concentrations (mean, 12.4 µg/ml±1.5 μg/ml) occurred 45 minutes following the highest dose of caffeine (7.2 mg/kg), whereas the peak theophylline level (mean 3.8 µg/ml±0.4 μg/ml) occurred 90 minutes following oral administration of aminophylline (mean theophylline, 2.6 mg/kg). Comparable peak increases in the forced expiratory volume in one second (FEV1), the forced expiratory flow during the middle half of the forced vital capacity (FEF25-75%), and Gaw/Vl occurred at 120 minutes following aminophylline and the highest dose of caffeine, indicating that caffeine is an effective bronchodilator but is only 40 percent as active as an equivalent molar dose of theophylline. Regression analysis revealed statistically significant dose-response relationships between peak increases in serum caffeine concentrations and increases in FEV1, FEF25-75%, and Gaw/Vl from baseline values. These findings have diagnostic and therapeutic implications regarding the use of caffeine prior to tests of pulmonary function and as a dietary agent, alone or in combination with theophylline.

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They should start a T Nation help desk. I wonder how much someone would pay for this? So much to sort through on the internet. People need a trusted advisor.

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Wow not even a syllable? I am shocked.

:thinking:

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Really? Dude was ungrateful as fuck after pan-handling for someone else to google search some stuff for him.

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Sorry my sarcasm is really bad. I better get off the forums :grinning:

Not good for ya.

2:32

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People, thank you very much.

Sorry for not putting a gratitude message earlier.

By the way, I thought the hearts I had put on the messages would mean thank you’s.

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