Thoughts on this?

Pharma
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I believe I’m quoting this correctly, I’ll try to find some reference sources for you all.

As I’m sure you know Jay Cuttler has multiple YouTube videos featuring a Dr. Rand Mcclain. If memory serves he (Dr. Mcclain) was quoting a Dr. Morgentaler saying “most men will not realize a substantial therapeutic benefit until levels are at 1,000ng/dl or above.”
I’m
I realize nothing is cookie cutter. But general thoughts on this? I know physicians tend to panic when they see something on the “high normal” range. Let alone with something out of reference range.

As always, thanks in advance!!

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TRT is about symptom relief. Could be at 600, 700, 1200.
Numbers are just that, numbers, They mean nothing.

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Surely hct will become more of a problem the further you push levels though?

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My very uneducated view is i’m sure at some point yes it would. However, just speaking for myself the highest mine has ever been is around 1500ng/dl. During that time PSA, and H&H stayed within limits.

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Was that with having to donate, or did your levels just naturally stay within limits?

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No, they just stayed within limits.

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Also,

This was with Test C 100mg/week and Clomid 25mg EOD.

*was really non compliant with the Clomid and ended up dropping it. Just stuck with the 100/wk. The Clomid made me feel awful.

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My HCT was 58.5 last last week, no issues. My blood pressure is on the lower end. High HCT on TRT is fine as long as you don’t have comorbid conditions where the high HCT would contribute to problems, example, sleep apnea, heart disease or plaque build up in the arteries.

With a secondary erythrocytosis there is an increase in blood volume which enlarges the vascular bed, decreases peripheral resistance and increases cardiac output. Therefore, in a secondary erythrocytosis optimal oxygen transport with increased blood volume occurs at a higher hematocrit value than with a normal blood volume. A moderate increase in hematocrit may be beneficial despite the increased viscosity.

There are over 80 million people that live higher than 2,500 meters and they develop a secondary erythrocytosis. Men in parts of Bolivia for instance have a normal range of HCT from 45-61%. These men are not at an increased risk of thrombotic events nor do they have to undergo phlebotomies to manage their hematocrit.

My endo’s take on my HCT at 58.5% after talking to a hematologist about my case →

I can’t tell you at what level of hematocrit is too high for you, but this is pretty high.

Be careful gauging success just about how you feel. History is full of stories of failures based on people who judge success based on feeling.

I’d recommend at least monthly monitoring of your levels at least for the Hgb/Hct.

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Please laugh. But, how do you send a private message on this platform??

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Never mind, From what I can find that has been taken away.

Back on topic…Systemloard, I know TRT isn’t a set it and forget it type o deal. However, once you are on a protocol that is working and stabilized for lack of a better term. Do you see issue with pushing Hgb/Hct out to every 6 months?