100mg will have risks, but this pertains to the significance of therapeutic value the drug has
After reviewing the literature, I’ve come to the conclusion that deca is riskier than testosterone, to what extent is unknown… but aside from neurological effect… I’d believe the difference in risk isn’t extreme (as in its not 5-10x more harmful)… we simply don’t know
Nandrolone itself aromatises/is 5a reduced, however the metabolites (and further downstream metabolites from the parent hormone itself, dihydronandrolone etc) aren’t supposed to be present within large concentrations in the human body (trace amounts yes… but even therapeutic amounts of deca flood the body with far more than what would be produced natural)
These synthetic metabolites have different pharmacokinetics compared to test, what effect regarding cellular regulation, other biological processes do these synthetic metabolites have? Esp in supra concentrations, we just don’t know… this was the case with the pill and it’s been found out hormonal contraceptive pills for women (depending on the type used) roughly triple the risk of blood clots etc. hormonal interference, specifically synthetic hormones alter homeostasis significantly, the downstream effects (this pertains to supra doses of test too) can be lethal
That being said, if things turn out well I’ll be running deca for a while (my cruise dose is… high) but then again I also don’t “cycle”, pertaining to 500mg+ dosages and don’t ever intend to so it’s a happy medium. I suffer from chronic pain and at this point I’d certainly choose deca over surgery, painkillers or just dealing with it. Not saying deca is good for TRT, but in certain instances I’d argue it can be justified.
The neurological effects can be rather profound
Interestingly a recent rat study came out going against the notion of prior studies indicating deca didn’t change morphological parameters of the rat heart (dose was low though)
Today post cortisone shot is my first chest workout in a VERY long time, can still work back, legs etc just fine (though shoulders I’ve had to be extremely specific regarding exercise choice). Did some rear delt raises yesterday after my workout/run… today my left delt is twitching, irritating but expected… shit happens, I’m very stubborn though. Unless pain/ailment is unbearable I don’t let something stop me from getting where I wish to be
Many also dislike the notion of intense cardio due to the inherently catabolic nature of extreme endurance exercise… I’m not too focused on purely aesthetics, I’m focused on what I enjoy… if running, cycling and whatnot makes me happy (running needs to be on a treadmill with a slight incline, and my weight does shift further to one side leading to muscular imbalance as I have nerve damage in my left ankle and thus physically can’t activate certain muscles within my left leg) then I’ll incoorperate such elements into my daily routine
It’s a risk/reward ratio/cost assessment one has to see here. In the guys case, offered deca under a docs supervision… if he wants to cycle and is aware of the risks it’s not a bad idea, better than/statistically safer using black market gear without supervision