Well, on 200 mg per week, I was at 1223 ng/dl. I pinned 62.5, 62.5, and 75 m,w,f. I pulled labs Friday morning. If it was a linear relationship, I would be at almost 4600 ng/dl at 750 mg/wk in the same pinning schedule.
They can’t be linear though… my TRT is higher than yours for those same TT numbers. You just need to blast some test and get us some numbers in the name of science!
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There’s also the lipases that break down the carrier oil, allowing the body to access the drug from the depot. Then the esterases that hydrolyze the ester, eventually releasing the active hormone. These enzymes act differently in different people, affecting absorption rates. As you said, this shit is complicated; so many factors influence our individual responses.
Wow wanna_be your free T is not even double with a TT of 4000? Am I reading that right?
I ask because when I blast my TT never gets to 4000 but my FT is always 4,5,6x the max range. Here are two different blasts with free T out the wazoo. I don’t get it.Is your SHGB exceptionally high?
I’m confused by his labs. It has two listing for free t. Anyone know which one is what we would normally call free t?
After looking, is it possible that the first is the trt lab result, and the second is during the blast?
@mnben87
I am assuming you are questioning wanna_be blood tests because they are not standard by any means?
Yeah, one of them is double range, and one is like many multiple times over (what it should be for a blast imo). I’m thinking the second is the free t in blast?
@wanna_be do you live in America? Do you use Labcorp or Quest? Those are the only two labs anyone trusts.
My SHGB is always very low, like 15. Also that is a labcorp test and yes, good ole US of A
This is what the description of the test I ordered was.
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@readalot what do you make of those labs? Everyone understands the normal total and free but the other one most, including myself seem to have never seen. Can you tell us more about that?
I certainly will not claim to know as much as @readalot but the first value is %free, the second is total free:
4003.2 * 0.77 = 3082.5
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See first two pages of review article above. Bioavailable (“free” + “weakly bound”) T assay is a very standard result that attempts to measure non-SHBG bound testosterone by precipitating SHBG bound fraction using ammonium sulfate method.
https://www.labcorp.com/tests/143255/testosterone-free-and-weakly-bound
Testosterone that’s left is the human serum albumin bound test plus free test. It’s a long story how all these tests and terms came to be and if you want the gory details read the review above. Bottom line is that free T isn’t the end all be all as I mentioned in above post. We don’t truly know the interplay of free T, SHBG bound T, and HSA bound T in the body and the specific roles of each.
HSA bound [ “weakly bound” ] T is the bastard stepchild T that never gets any love on the forums or by many providers.
Look here if you want “simple” math on how to estimate each bucket:
If you plug in your numbers here you can test theory vs your individual experimental data from labcorp:
http://www.issam.ch/freetesto.htm
In your particular “hit the gas” example the majority of the T is protein/HSA bound T, not SHBG bound, not free. No love for the poor HSA bound T!!
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