T Cyp Burns, Itches, Hurts

Just bumping this to see if anyone has new ideas. Started T Cyp again and it has started burning and itching and hard knots again - does this with both T Cyp and T Enan which are 2 different oils

I have seen many people mention this but not much as to what to do about it. I inject Watson T Cyp 60mg 2x/week sub-Q. The injection sites itch, burn, hurt and turn red and continue to stay that way for at least a week. My HCG shots have no issues.

Is it typically the cottonseed oil or the Benzyl Alcohol or the brand?? What seems to be the best way to correct (new brand, compounding, suck it up and live with it…)?

Thanks

This same thing happened to me when i started sub Q, big reed hard gold balls in my leg. it was suggested to me, not to pinch up the fat so hard and this seems to have solved the issue. Just squeeze the fat jsut enough to keep the needle out of the muscle. Everytime i really pinched it up hard, i would get the red itchy golf ball.

I hope this makes sense, i dont know how else to explain it.

[quote]Ned wrote:
This same thing happened to me when i started sub Q, big reed hard gold balls in my leg. it was suggested to me, not to pinch up the fat so hard and this seems to have solved the issue. Just squeeze the fat jsut enough to keep the needle out of the muscle. Everytime i really pinched it up hard, i would get the red itchy golf ball.

I hope this makes sense, i dont know how else to explain it.

[/quote]

I will try that. I’m not real skinny but I have a hard time getting a good grip on some fat. Now that I think about it, I do pinch it real hard probably because I’m worried about slipping because of how hard it is to inject the oil through those tiny syringes. Thanks

What size syringe? 0.5ml will inject faster than 1.0ml

[quote]KSman wrote:
What size syringe? 0.5ml will inject faster than 1.0ml[/quote]

I’m using a 0.5 ml 29 gauge syringe. I’m probably just impatient as I don’t like a needle stuck in me longer than I have to!

Also, I do all my injections in the stomach area. Are less reactions reported in other areas?

Are less reactions reported in other areas?

I get bumps on my belly, but not my legs and other guys vise versa

I was sensitive to SQ shots for a while, think that my immune system got weird about it. Then started to get more aggressive with the alcohol prep pads; scrubbing the injection site. I think that things improved after I did IM for a couple of weeks. Hard to know what that means, but that would give the immune system a different view of things. Also after my near death surgery/infection 2.5 years ago, my injections would get inflamed, another hint that there was an immune system component. Some T cyp has more than T ester, oil and BA alcohol and I wonder about that. And some T can be made from soy base stock and someone who has a soy alergy can be affected by that.

[quote]KSman wrote:
Are less reactions reported in other areas?

I get bumps on my belly, but not my legs and other guys vise versa

I was sensitive to SQ shots for a while, think that my immune system got weird about it. Then started to get more aggressive with the alcohol prep pads; scrubbing the injection site. I think that things improved after I did IM for a couple of weeks. Hard to know what that means, but that would give the immune system a different view of things. Also after my near death surgery/infection 2.5 years ago, my injections would get inflamed, another hint that there was an immune system component. Some T cyp has more than T ester, oil and BA alcohol and I wonder about that. And some T can be made from soy base stock and someone who has a soy alergy can be affected by that.[/quote]

Guess I will try my legs and hope that it isn’t an underlying immune issue.

KSMan - I have another thread but I will ask the question here for your input. Been on T Cyp for about 6 months. Bloodwork at 1 month showed TT increase from about 300 to 1027 and DHT up to 40. 6 month bloodwork shows my TT dropped to 450 and DHT was <19. Both samples collected in the morning about 30 hours after an injection. Any idea why it would drop like that? Doctor upped my dose another 20mg per week and holding steady with the HCG 250 mg 2x/week.

Thanks

Same brand of T? Same injection frequency? Same lab doing the work?

Some guys metabolize T faster than others, not seen a guys change that way during TRT.

That was a huge change. Lab errors also occur.

Did E2 change?

[quote]KSman wrote:
Same brand of T? Same injection frequency? Same lab doing the work?

Some guys metabolize T faster than others, not seen a guys change that way during TRT.

That was a huge change. Lab errors also occur.

Did E2 change?[/quote]

Same lab, same frequency, same dosage, same brand, everything. Yes E2 changed it went from 44 to <16 and I have only been dosing arimidex at 0.2mg 2x/week. (sorry I am not giving units but my labs just vanished off the docs website but they are standard units that you mention)

So in summary, I kept everything the same and my TT, DHT and E2 all dropped significantly.

Suggest that you get a quick lab for TT, FT and E2 in 2-3 weeks to help get your dosing right.

Anastrozole dose needed to match serum T levels and when that dropped E2 production would drop plus the anastrozole dose was too much for that; so E2 gets even lower. This confirms not a simple lab error.

140mg may not be enough, when we see this problem, it seems that the few that we have seen here so affected needed 300mg/week. Those guys have not stood out with any obvious complicating issues that I have noticed.

I think that the explanation would have to be something involving the liver.

And see if you can try a different brand of T to see if that affects the injection site issues.

[quote]KSman wrote:
Suggest that you get a quick lab for TT, FT and E2 in 2-3 weeks to help get your dosing right.

Anastrozole dose needed to match serum T levels and when that dropped E2 production would drop plus the anastrozole dose was too much for that; so E2 gets even lower. This confirms not a simple lab error.

140mg may not be enough, when we see this problem, it seems that the few that we have seen here so affected needed 300mg/week. Those guys have not stood out with any obvious complicating issues that I have noticed.

I think that the explanation would have to be something involving the liver.

And see if you can try a different brand of T to see if that affects the injection site issues.

[/quote]

Thank you very much for the response

Here are my latest results that I was referencing. My Free T has always been reported as high, even when my total T was at 300, but I wonder if that is because it is a calculation rather than an analytical value and something is goofy elsewhere that would nullify that calculation???

I find the gluteu medius area the best (muscle just below and to the rear of the hip, google it). Many times I cannot even feel the injection there. I just inject directly with a 1/2 inch insulin needle without pinching, so it is possible the injection goes into the muscle, not the fat, but it is still quite superficial and there is no pain or lumps ever.

[quote]seekonk wrote:
I find the gluteu medius area the best (muscle just below and to the rear of the hip, google it). Many times I cannot even feel the injection there. I just inject directly with a 1/2 inch insulin needle without pinching, so it is possible the injection goes into the muscle, not the fat, but it is still quite superficial and there is no pain or lumps ever. [/quote]

I will give spot a try. I tried the front of my leg yesterday with the HCG just to see how it goes, and I thought I was going to need vice grips to hold the skin! I don’t have any slack there so I can’t imagine doing the T shot there sub-q. Thanks

SHBG must be somewhat low.

Can you check your body temperatures as per the thyroid basics sticky?

[quote]KSman wrote:
SHBG must be somewhat low.

Can you check your body temperatures as per the thyroid basics sticky?[/quote]

Will check it over the next few days and post back. I keep waiting for my thyroid to be off since most of my family has ‘dead’ thyroids and I had a nodule about 15 years ago. (although previous results say it is ok (TSH 1.5 and fT4 1.2). Plus I had the whole panel run years ago, but now is now!

[quote]seekonk wrote:
I find the gluteu medius area the best (muscle just below and to the rear of the hip, google it). Many times I cannot even feel the injection there. I just inject directly with a 1/2 inch insulin needle without pinching, so it is possible the injection goes into the muscle, not the fat, but it is still quite superficial and there is no pain or lumps ever. [/quote]

Injected at this spot this morning - first injection in 6 months that doesn’t burn, itch and hurt within minutes! So far all is good. Thank you

As long as you know the technique to avoid major nerves etc.

[quote]KSman wrote:
As long as you know the technique to avoid major nerves etc.[/quote]

Yeah, I read about dividing buttocks into quadrants and only hitting the upper right quadrant. I didn’t see any major nerves in the outer upper right side and I pinched lightly to still get it into the fat.

Past three morning body temps 97.1, 97.5, 98.3.

I inject my upper quad while sitting. I inject my quads on the the spot just before the crease between your upper and lower torso.
I used to pinch and then inject, but using the 0.5 29g pins and that space, you do not need to pinch. I am not sure if its Sub-q or shallow IM, but its comfortable and does not swell. I think the trick is to inject the needle very fast, almost like a dart, not having to pinch the skin frees up your other hand to hold the barrel of the syringe while you use your other hand to push the plunger with your thumb. I think the steadiness of this technique (and subsequently the needle) minimizes the damage that leads to the redness and inflammation.