[quote]ActivitiesGuy wrote:
[quote]jbpick86 wrote:
Interested to know your view on the chickenpox vaccine, its role in preventing/contributing to shingles cases, and its necessity? I ask you as you seem to be the most knowledgeable and its a relatively new vaccine for a relatively harmless disease.
[/quote]
TBH, I don’t know enough to comment there. I should ask my pal the infectious disease epidemiologist for his opinion.
(relevant disclosure: I’m a PhD epidemiologist, but my research has been in mostly chronic-disease work: cardiovascular disease, diabetes, women’s health, and I’m about to go back to the cardiology world - so I have never actually worked infectious disease stuff, although I have friends that do)
FROM WHAT I CAN TELL:
-
The virus that causes chickenpox, varicella zoster virus, remains latent in nerve cells even after we fight off the infection as kids.
-
As we age, the immune responses that keep varicella zoster virus dormant in the nerves weaken and it can rear itself again.
-
The lifetime risk of shingles is estimated to be 32 percent, and approximately 50 percent of those living until age 85 are expected to develop shingles.
-
I have never known someone with shingles, so I don’t have a good grasp on the morbidity and mortality associated with the disease. It sounds like it’s no fun.
-
I don’t really know whether vaccinating against chickenpox would prevent shingles in later life. Conceptually, it makes sense, but I can imagine that the virus might still linger in some folks that get the chickenpox vaccine, become carriers of the virus but never feel the illness, and later develop shingles as their immune system weakens and the dormant virus becomes active. I don’t know enough about virology to comment.
One more-serious final point worth raising: to most of us, chickenpox is a harmless disease. Something we all got as kids and got over in a few days. But the varicella virus can be life-threatening to someone that’s immunocompromised. Kids with leukemia, anyone with cancer or HIV, etc. They rely on the fact that most everyone around them is vaccinated. So that’s the best qualitative argument I can come up with “in favor” of the chickenpox vaccine (incidentally, this extends to flu shots as well). You can get the chickenpox at age 5 and be done with it. But if your 5-year-old kid gets the chickenpox and goes to gymnastics or the playground and plays with a 5-year-old kid that has a rare childhood cancer and is enjoying one of his rare days in the sun, that kid might die from it.[/quote]
Thanks, I was reading at least one summary of the CDC’s report that said that due to the chicken pox vaccine becoming more common that instances of shingle would likely increase because adults would receive fewer exposures to the virus and those exposures acted as a natural booster to the bodies immunity to the virus. I dunno, I don’t consider myself an anti-vaccine freak at all but my wife and I have been given some pause on the chicken pox vaccine. However, if they don’t contract it young, apparently it is much harder to deal with as you get older so maybe the vaccine would make sense. But in several cases the vaccines effectiveness has been shown to wear off in 5-8 years. I dunno, lot to think about that one though.