Steroids and Antibiotics

Whenever I come across information on steroids and their side effects, Accutane is usually the recommended treatment for the acne one might get while ‘on the juice’.

I was just wondering why nobody uses plain old antibiotics to combat the acne, while on steroids.

Some of the information I’ve come across on the web says that the antibiotics, such as tetracyclines, inhibit protein synthesis so would therefore be contraindicated with steroid use for bodybuilding purposes. In other words, antibiotics may inhibit the tissue building process and make the steroids less effective.

I’m not really sure if this is the case - maybe antibiotics only inhibit protein synthesis within the skin and not the muscle, who knows?

But I’m looking to start a cycle very soon and am just wondering if it would be okay to use antibiotics for the acne. Accutane has some serious side effects, such as causing birth defects in women and mental problems or suicide. I already have a history of depression, so I think Accutane would make it worse.

Accutane would not be my first or second choice becase of the side effects…There is some OTC stuff you can check out first and some practices that go right along with that such as showering after working out, etc. Physoderm is a good anti bacterial soap to use also…

[quote]JohnnyBlaze wrote:
Whenever I come across information on steroids and their side effects, Accutane is usually the recommended treatment for the acne one might get while ‘on the juice’.

I was just wondering why nobody uses plain old antibiotics to combat the acne, while on steroids.

Some of the information I’ve come across on the web says that the antibiotics, such as tetracyclines, inhibit protein synthesis so would therefore be contraindicated with steroid use for bodybuilding purposes. In other words, antibiotics may inhibit the tissue building process and make the steroids less effective.

I’m not really sure if this is the case - maybe antibiotics only inhibit protein synthesis within the skin and not the muscle, who knows?

But I’m looking to start a cycle very soon and am just wondering if it would be okay to use antibiotics for the acne. Accutane has some serious side effects, such as causing birth defects in women and mental problems or suicide. I already have a history of depression, so I think Accutane would make it worse. [/quote]

Yes, a lot of pro’s and bbers in “the know” use the tetracyclines.

Go to you’re general practitioner and tell him you tried some benziq wash that a friend had. Tell him it worked good for you and you should be fine. Benziq is the best I’ve used. Accutane is hell as far as liver tox goes. Be carefull and get you’re blood panels done like you’re supposed to.

Good luck bro.
Biscuite

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Accutane, being highly liver toxic as others have said, makes it terrible, in my opinion, for anyone using AAS. As far as an aesthetic drug, it is incredible that is even FDA approved (though the FDA is the FDA).

AAS increases acne by increasing oil (or sebum) production from the sebaceous glands, and is inherently tied to the increases in hair growth that are seen from AAS. You cannot expect to be acne-free while using androgens, being that their functions include such affects of the sebaceous glands.

That being said, reducing oil through regularly cleaning, through topical retinoids, topical anti-inflammatory drugs (both OCT and RX), etc. etc. are all good alternatives to oral retinoids, such as Accutane.

Some have also had luck with photo therapy and (with a small similarity) use of the gray market peptide Melanotan.

Talk to a dermatologist (who is also bound by confidentiality), and she what they think might help.

The tetracyclines inhibit protein synthesis of bacteria, but not of mammals or our other animal/vegetable/fungal relatives (eukaryotes.) This is because our ribosomes differ from those of the bacteria, and the tetracyclines target a site on the ribosome that differs between theirs and ours.

In other words: not to worry.

Sorry to hijack-I don’t feel my question warrants another thread…

I have read some contradicting information on the webz, if someone would be kind enough to clarify the following please: My understanding is Doxyxyxline and tetracycline are similar but not the same thing? Tetra is the primary choice but most doctors will ‘start’ you on Doxy?
I originally read that Doxy is part of the Tetracycline ‘family and it s a form of tetracycline’ Either way I am sure Doxy is for for my purposes but it seems, based on the research I have done that Tetra would have been better.

I have some Doxy I have been keeping on hand and now need to use it as I have started to get cystic acne on my back. I have read that 100mg twice daily (with food) and topical cream is a good start for 30-60 days. I am on 600mg cyp and 400mg Masteron, I have just dropped the masteron (none this week) and adex is currently 1mg EOD as of the beginning of this week, it was E3D and I was fine, though today things on my back were visibly worse and I feel like I have fucking lead shot under my skin. I followed the instructions I found and have taken 200mg today, in separate doses.

Anyone with experience of Dosycyxline your thoughts are welcome…

Bonez, I remember you saying a Deca cycle gave you cystic acne and you used Doxy for 6 weeks, could you tell me the dose you used please?

Also, should I expect it to come back when I cease use? It may be the masteron as I generally use test only, last masteeron run was only 200mg a week years ago with no problems, I don’t tolerate tren well and have had cystic acne before from 200mg test a week, which I sorted out by uping the adex dose and replacing my shitty research adex with ‘proper’ adex. My adex now is definitly real.

I am seriosusly considering doing the acutane course and permanently ridding myself of zits and acne. I appreciate that as an AAS user I am going to have some skin irritation and the odd zit, and yes it’s self inflicted, but these cystic lumps are fucking evil-I never got acne when I was a teenager-a few zits yes, but I really feel for any teenagers who had this shit on their faces.

Thanks, BB

No experience with those drugs. But I have used minocycline with great success. Maybe minocycline and the drug youre talking about are the same thing under different names, I dont know. I used a generic brand. 2 doses a day. I think it was 200mg/d.

My acne has not come back and Im almst certain the acne wsa from out of control estrogen levels. I was running a tiny amount of underdosed adex with test and dbol. The dbol is when the acne got worst, from the methylestradiol IMO. Never had acne on (any) cycle when using real adex and just a minor amount during PCT (acne from SERMs is also pretty common, but its definitely not cystic acne; just a few blackheads or small whiteheads every now and then.

[quote]buddaboy wrote:
Sorry to hijack-I don’t feel my question warrants another thread…

I have read some contradicting information on the webz, if someone would be kind enough to clarify the following please: My understanding is Doxyxyxline and tetracycline are similar but not the same thing? Tetra is the primary choice but most doctors will ‘start’ you on Doxy?
I originally read that Doxy is part of the Tetracycline ‘family and it s a form of tetracycline’ Either way I am sure Doxy is for for my purposes but it seems, based on the research I have done that Tetra would have been better.

Thanks, BB[/quote]
I worked on a research project examining the effects of doxycycline of aortic abdominal aneurysm, so hopefully I can answer this intelligently.
Tetracyclines are a broad class of antibiotics, to which doxycycline belongs. Of course, to confuse people, there is also a specific antibiotic called tetracycline.
Minocycline, doxycycline, oxytetracycline, tetracycline, chlortetracycline all belong to Tetracycline class of antibiotics.

Thanks for the quick responses guys :wink:

I’m certain the small amount of cystic acne I had before was from elevated E2, and I sorted it out simply by upping the adex as per Bonez’s advice.

Perhaps this time its from the Masteron? Strange; I was using Masteron Prop-no problems-switched to masteron Enan (to reduce the injection frequency and 'cos I get it cheap) and the problems seemed to start at approximately the same time. I can’t tolerate Tren at more than 25/30mg ED and whilst the Masteron made me feel great, maybe the androgens are what caused the skin aggravation?

I usually have a couple of zits on my back or one on my shoulder at any one time, but these Cystic things are fucking evil, totally different and take months to completely disappear so I need to get rid of them quick sharp, whilst I accept that as an AAS user a couple of Zits here and there are par for the course.

Yesterday I took 200mg of Doxy, which a quick search recommended as a standard dose. I applied topical cream and the lumps which ‘surfaced’ yesterday are already drying out and no new arrivals today thanks fuck. The adex I have is decent, though could be under-dosed,I do in fact have some pharm grade blister packed adex which I use to take on holiday etc, I will switch to this and see if that helps.

I never got acne from SERM’s, I did some food muscle testing with BBB and his exact words were ‘You’re a paradoxical mother fucker’ (charming) so perhaps that puts me in a minority where certain guidelines won’t help me and I will possibly react differently to many?

Thanks :wink:

[quote]600lb Gorilla wrote:

[quote]buddaboy wrote:
Sorry to hijack-I don’t feel my question warrants another thread…

I have read some contradicting information on the webz, if someone would be kind enough to clarify the following please: My understanding is Doxyxyxline and tetracycline are similar but not the same thing? Tetra is the primary choice but most doctors will ‘start’ you on Doxy?
I originally read that Doxy is part of the Tetracycline ‘family and it s a form of tetracycline’ Either way I am sure Doxy is for for my purposes but it seems, based on the research I have done that Tetra would have been better.

Thanks, BB[/quote]
I worked on a research project examining the effects of doxycycline of aortic abdominal aneurysm, so hopefully I can answer this intelligently.
Tetracyclines are a broad class of antibiotics, to which doxycycline belongs. Of course, to confuse people, there is also a specific antibiotic called tetracycline.
Minocycline, doxycycline, oxytetracycline, tetracycline, chlortetracycline all belong to Tetracycline class of antibiotics.[/quote]

BUMP…

I have been on 200mg Doxycycline for two weeks now, and whilst this has prevented the arrival of any new cystic type of acne lumps I am still getting ‘spots’ on my face and have a few new arrivals on my chest. I have completely ceased use of any vitamins and fish oils and am only using a low carb protein powder.

There is absolutely no consistency as to when these spots come and go, the cystic acne has struck whilst of been on 200mg test and 1000mg tets per week. I bumped the adex up to 1mg EOD and that didn’t stop it either. I have had no spots whilst I have been not training and injured whilst eating whatever I wanted (whilst still ‘on’) and had acne strike whist I was eating clean and training hard. I do have a sweet tooth but suppress that by eating chocolate protein bars-again I cannot pinpoint one particular habit/supplement/steroid that seems to be consistent with this, I have literally eliminated everything I can think of that might be causing it-I am currently on 400mg week test (I do HRT) with 2mg adex a week.

I can’t keep going to bed wondering if I’ll wake up with a fucking enormous cystic lump growing on my neck that will take literally 2 months to clear completely.

I am not on any medication either apart from the HRT. I have decided I am going to do the preventative accutane course. I have spent some time researching this and not surprisingly have come across plenty of conflicting information. I am of the understanding that a course of accutane can physically prevent acne from ever returning-which sounds fantastic to me.

My first concern was that there is typically an acne ‘rebound’ where acne initially worsens when you begin taking the drug, but read that this can be combated and usually prevented by tapering upwards like 20mg a day for the first month, working up to as much as 120mg a day for a ‘large person’ I don’t think I need this much as I am fortunate enough not to suffer from serious acne, I am guessing this dose is for more serious cases. Can anyone with experience of accutane offer any advice on dosage and duration please?

Thanks
BB

In the meantime I am going to continue with the doxycycline and try a protocol on top recommended to me in the nutrition forum (sorry can’t remember the name of the poster so I can attribute credit to them) of 10,000IU ED Vitamin A, 50mg Zinc and 400IU Vitamin E, on top of this I am using proactiv on my face.

I feel like a fucking woman with all those face treatments LOL

Just saw a commercial not 10 minutes ago about Accutane. The company is getting sued for causing Inflammatory Bowel Disease, Crohns Disease and Ulcerative Colitis. No personal experience, but from what I’ve read Accutane is straight up poison to the body.

I get the cysts sometimes, so I can sympathize they suck big time, but I would definitely be a little wary of Accutane. If you have the cysts under control with antibiotics, have you tried Cetaphil antibacterial bar soap for the other little spots? Works great for me. I shower with it 3 times a day on cycle and I’ve had minimal breakouts (I’m prone to acne). Without it my skin can get pretty bad.

Thanks, I am going to fully explore every other option before going ahead with this, I ordered my stash last week in a moment of desperation. If things get worse I’ll go to the doctor, provide an honest explanation and get some blood work done and see if KSman can help.

I am slightly reluctant to do this as working overseas may be an option for me in the near future, and I don’t want prospective employers to reject me because of this, although if I could somehow be prescribed HRT that would be of great benefit as obtaining testosterone overseas, possibly illegally may well tricky to say the least.

The only alternative is to have tests conducted at a very expensive rate in a private clinic without disclosing my real name, this would probably be the best way to try and obtain prescription HRT.

[quote]BONEZ217 wrote:
No experience with those drugs. But I have used minocycline with great success. Maybe minocycline and the drug youre talking about are the same thing under different names, I dont know. I used a generic brand. 2 doses a day. I think it was 200mg/d.

My acne has not come back and Im almst certain the acne wsa from out of control estrogen levels. I was running a tiny amount of underdosed adex with test and dbol. The dbol is when the acne got worst, from the methylestradiol IMO. Never had acne on (any) cycle when using real adex and just a minor amount during PCT (acne from SERMs is also pretty common, but its definitely not cystic acne; just a few blackheads or small whiteheads every now and then. [/quote]

Bonez: Thanks I checked Minocycline out, and, according to my research it is the broadest spectrum of the Tetracyclines. Meaning it would have been a better bet for me than Doxy, so is what I’ll try next if I’m not successful with what I’m on now.

So far this week one new ‘bloch’ (not a zit/whitehead or cystic lump so don’t know how else to best describe it) on shoulder and one painful compact spot on face, but since yesterday when I started the Vitamin A they feel kinda better so fingers crossed.

Just in case this may be of interest to anyone…

In one last desperate attempt to rid myself of these diabolic zits and cystic lumps I finally decided to switch over the types of test I was using-not of manufacturers but esters. I remembered that I had not seemed to have ever had problems on Sustanon or Omnadron, the Cypionate I was using couldn’t have been ‘faulty’ because for several months preceding the skin problems I hadn’t had any trouble with skin irritation.

It seems, somehow that I develop an ‘intolerance’ to the testosterone I use and need to switch every 3 or 4 months. I’ve switched to T400 and the zits and lumps are literally disappearing with no signs of new ones, very strange but I’m not complaining.

I’ve also stopped the Doxyxyxline which seemed to stop the acne but cause more zits, so maybe I’m allergic to it ;-(

[quote]Bill Roberts wrote:
The tetracyclines inhibit protein synthesis of bacteria, but not of mammals or our other animal/vegetable/fungal relatives (eukaryotes.) This is because our ribosomes differ from those of the bacteria, and the tetracyclines target a site on the ribosome that differs between theirs and ours.

In other words: not to worry.[/quote]

With Tetracycline be careful because it turns your teeth gray. I had rather have some zits than a busted ass grill.

Also to stop the ance while I am on, I use a cleanser called Cerave and an OTC product called Cellex-C. It is a vitamin C serum that you apply 2 times a day and it kills the bacteria without making your skin dry. It is the only thing that has ever worked on my face and I have tried everything. All of their products work awesome, but they are expensive as hell. ebay is the cheapest place to find them.