Yes a fast acting formulation applied in the morning would mean low levels in the evening. Check out this thread:
A very fast acting formulation pulsed once or maybe twice daily may also have minimal negative feedback on your HPTA or let you keep some function.
Creams, troches, and gels would all be testosterone in a base/solvent.
The testosterone ester injectables would be testosterone esterified with a fatty acid to create a time release formula.
So side effects would have to do with the pharmacokinetics (how the testosterone is metabolized and processed by the body). The different routes of administration allow one to control how much your blood levels rise and the peak / trough / duty cycle of the pulses.
Compare plot above (nasal gel) vs plot below (scrotal cream):
A PM dose of the cream applied on skin is going to be with you for a while and into the evening. Nasal gel would be in and out in a few hours.
Honestly I appreciate the effort @tareload puts into his posts. Probably not as much as I should either. The information out there is extremely convoluted and often inaccurate, but I think heâs been consistent in his messaging and sharing of information that one likely wouldnât find otherwise.
Going out of your way to talk shit about him shows more about you than it does him.
As I have said many times, any one is free to challenge and point out the BS in any of my posts. If you or others find some please share. I donât prop up my arguments with any credentials or appeal to authority. You donât know what I do in the real world. And it doesnât matter. Folks will have to judge the applicability and validity of the information I present based on content only.
You obviously are a guy who has zero clinical experience and are not a MD. You would not be sharing the nonsense you do, which is not reality of an MD. You are solely focused on graphs and shit⊠zero clinical exp.
I know what i am doing. I take a dose that works for me and i feel great. Zero problems, but you say my dose will kill me and i donât need it.
@enackers Glad to hear your protocol is working for you. I wish you health.
EDIT: awesome, looks like I can still get posts approved if I donât include too many details or links. Iâll keep that in mind. Maybe Iâll start âchattingâ like many others on here. :-).
That is not even close to what i do. I actually explain the benefits of estrogen and why nobody with that knowledge at hand would ever want to consider an AI.
Obviously you guys miss the point.
You are blocking a hormone that is cardio protective, produces libido and many other benefits in the body that will give you health and satisfaction in life.
Very few men will ever need an AI. The problem is that most of these younger crowd are senstiive to every single ache and pain. Literal snow flakes. Even when they discuss a topic, they cannot hold it together and try to understand what im saying. They pull together a huge case of confirmation bias and say âsee you are wrongâ, but never stop to realize that the majority do not take an AI today and are fine. Thats what you are doing.
But no. your emotions will over run your logic and not realize the truth behind what im saying.
You are always blaming E for everything, but cannot ever realize that maybe its not the E.
Simple statement: take an ai and put yourself at risk for a heart attack and poor health in every sector of your health.
How many people have stopped an ai and said âi didnt know i could feel this good on trtâ⊠about a dozen ive talked to. How many stopped an AI, after thinking they needed it, and actualy got off it and said âmy blood pressure dropped, my heart rate dropped, cholestoral dropped, and libido is backâ.
Maybe you are that guy who is that rare occurrence, but i am not speaking to you. Im speaking to the majority of men who will never need an AI, but are led to belive its something they need.
Those new comers are my focus. I want them to find the health they deserve, and not years of aches and pains due to some idiot telling them to mix an AI with their TRT.
Thatâs because they are growing up in a more toxic environment that the older crowd. My sister ran a daycare for over 20 years and began to notice her kids had severe food allergies unlike decades early and no two kids could eat the same food.
The days of feeding the kids the same meals are over.
Ever notice how the men 50> seem to not have troubles with TRT and dial in the easiest?
As for the AI argument, AIâs are bad for most men, to what degree is individual, but sure some can get away with using them. The dangers long term isnât good and anyone taking them is at risk.
Because you are blinded by your bias and cannot remove your emotions from the way you feel. Itâs as simple as that, and until you can remove that bias, you will never realize the truth behind the science. You will run around telling everyone you are right, because you have a personal experience that says so VERSUS the facts of the matter.
Estrogen is the most beneficial hormone for our wellness and women even more so.
Enjoy⊠let me know in 1 or couple years how that mental state, bone density, heart health, sexual health and overall CV health is doing.
100% stand with you on that brother. I agree, the risks are too high for men who take an AI. They are playing with their mental and physical health and wellness.
i am not using my personal experience. I am using my doctors personal experience, who stopped posting here because non medical experts, without any clinical experience, and only self realized biases would argue with him.
Including Dr. Rouzier, who is known by any HRT doctor are the expert in HRT . hes an educator and close mentor of my doctor.
I simply echo what they say and they also sent me the literature they use to backup their methods.
If i sent you that literature, you could read it and decipher for yourself how fucking vital E is to your wellbeing. If you did that, then you would stand by the facts and realize that blocking your E is the last thing one should do. you would find other ways to deal with any symptoms you have if E is actually your problem, and not something else.
Lastly, its very clear on this forumn. The guys who dont take an AI rarely have issues related to T. The guys who take an AI are always complaining about one or another issue. Libido, cholestoral and just not feeling good.
I like to have some E2 as I need it, whoâs arguing that? If I am âblockingâ my E2 itâs not to 0. I know crashed E2 is bad as I had untraceable E2 pre TRT. What else you got for me?
You seriously sound like Danny I too wouldnât be surprised if you are Danny himself. You donât want to listen and ignore things being told to you. At 80-100mg per week I donât need or use an AI, but if I go higher dose and I need to micro dose AI while still maintaining E2 levels that arenât low, like why canât you guys get that through your head? Why?
And thatâs MY experience, this is what happens to ME, and thatâs what I have to do to make things work for ME. Doesnât matter if I âwait it outâ for months and months, doesnât matter if I inject subq or IM, doesnât matter if I inject everyday. I have trialed and errored and I know in MY case some estrogen is amazing and has made me feel better than having crashed E2, but I know I have a cut off, no matter what my TT/FT is.
Thatâs 175mg a week with 0.0625 arimidex eod. I would say that is some damn good blood work including liver and cholesterol in which AI is supposed to be a demon for. I am done playing this game and listening to a community who bans people left and right simply for questioning methods, and having so many of its members consist of dudes with ED or gyno.
All i did was tell you why and what. Thats it and now listen to you.
I relay the proper information based on medical literature and you literally decline to acknowledge. instead, you go off on confirmation bias again. I can share that literature.
Simple point in caps so you dont miss it. No im not telling you to increase your E. No im not telling you to increase your E. No im not telling you to raise or sky rocket your E strogne levels. im telling you to manage your dose of T via frequency or quantity rather than an AI. Simple as that. Keep your E Lower, just dont use an AI. CLEAR?
WHEN YOU REALIZE HOW VITAL E IS TO A MAN OR WOMANâS HEALTH, YOU WILL SHY AWAY FROM, AND BE VERY VERY SCARED TO MODIFY / MANIPULATE / LOWER YOUR ESTROGEN LEVELS USING AN AI.
BECAUSE YOU WILL REALIZE THAT THOSE AI PILLS MIGHT BE LOWERING E IN AREAS LIKE THE HEART, BRAIN, BONE, ORGANS, AND ETC. AND THE THOUGHT OF HAVING A HEART ATTACK, OR RUINING YOUR LIBIDO, OR BREAKING A BONE IS FRIGHTENING.
AI DOES NOT BLOCK E IN ONE SPECIFIC AREA, IT CAN BLOCK IT ANYWHERE IT WANTS TO. FOR ONE MAN IT MIGHT CAUSE LACK OF LIBIDO. FOR ANOTHER IT COULD BE THEIR ENDOTHELIAL LINING. ANOTHER MIGHT NOTICE THEIR BONES HAVE LOST DENSITY.
It is obvious that my doctors and Dr. Rouzierâs methods work⊠You never see people who are under their care complaining that their E is out of control or that they need an AI. You just dont see it , and he has hundreds of patients/ thousands over the years. Its an obvious 5 star review of him and Dr. Rouzierâs methods.
I hope you realize what i am saying and that your responses make no sense when you look at my comments. You totally missed the point and got very ⊠well⊠you know.
