Starting Daily Anastrozole. I Don't Care What You Say

Pharma TRT
143

  1. If you actually looked at these papers, it would be clear as day that they have nothing to do with unhealthy levels.

  2. Aromatase gene mutation… an exception, yes. I’ve seen one case in tens of thousands of cases. I’ll bet you the keys to my Lincoln Navigator that nobody in this forum has that gene mutation.

  3. Please demonstrate, using your own evidence (which you still have not provided) what level of estradiol is harmful.

  4. You’re asking me to post evidence. I’ve sent you a shit ton of papers and you haven’t provided diddley squat. Perhaps you can provide something in return first because, for the umpteenth time, you haven’t provided anything.

  5. I can’t discount your studies yet as you haven’t sent me any studies. Again and again. Not sure how many times I have to say you haven’t provided me anything.

  6. You’re asking me to provide something that supports my position, and, again, I’ve provided a ton of papers demonstrating benefits of estradiol and why it should never be blocked. You have provided nothing yet you want me to provide more evidence?

Can you be more stupid? I don’t think you can. I believe you have reached your genetic potential in this department.

Even if you decided to ignore all the literature, which I know you did, and just skip to the conlusion of the first paper, you would have read the following:

Recent evidence has demonstrated that many biological actions historically attributed to testosterone are instead, at least in part, mediated by its aromatization product E2. The data are strongest for effects on bone, fat mass, insulin resistance and VMS. The relevance of these
data is that clinically efficacious treatment of male hypogonadism is best achieved with testosterone, which provides ‘three hormones in one’ – testosterone, DHT, E2. Conversely, this evidence raises caution regarding the use of selective androgen receptor modulators, nonaromatizable androgens and AIs for male hypogonadism, and emphasizes the need for better understanding of the tissue-specific effects of SERMs, which are also used off label by some practitioners for this purpose. They also suggest that E2, either as sole ADT or as add-back to conventional GnRH analog-based ADT, may be a promising treatment to mitigate some of the adverse effects of ADT given to men with prostate cancer.

Where do they say that there was a limit in serum levels where managing it with an anti-cancer medication designed for women was required? They didn’t. Why? Because there was no evidence of that being the case. Just like there was no evidence that estradiol causes you to grow a third testicle, or a second head, or a tail. If they saw estradiol doing anything, they would have listed it, because they listed all their findings in great detail.

Either provide some god damn evidence or stop commenting. You’re the epitome of a forum troll right now.

144

Show me ONE!

146

No… the moron part I can actually demonstrate as indicated above and anyone who reads English can attest that I have provided sufficient evidence to demonstrate you being a moron. Case closed.

147

Do NOT respond to each thing. PROVIDE EVIDENCE. I only want to see evidence at this point. I don’t want to see anything else.

148

And then people wonder why I get frustrated. I provide a ton of information, a ton of evidence, I get nothing in return, get told my evidence is false yet they provide me gifs of doing a Google search.

This is how stupid some people are. Yes, it’s beyond frustrating.

149

Thank god you got me off the hook for that because honestly we agree on most things. You didn’t post studies though. You posted meta analysis papers with a couple studies that are too small to be considered clinical.

The burden of proof is on you. I am saying hormones within healthy ranges is generally safe. Prove me wrong or prove yourself right. You’re the one making the claim that goes against established medicine. That estrogen can go as high as it wants 19,999 times out of 20,000. The fact that you are name calling like a flustered woman on her period supports my stance that my preference would be to not be like you. You might like it, and that’s great, and I still like you, but its not for me. We are all unique. I truly don’t understand why you are so inconsolable, but then again, there have been many times in my life where my interaction with estrogen has left me confused.

3 Likes
150

I don’t know how else I can be more clear:

In all the studies of estradiol, in the last 80 years of study, nobody has ever found an amount deemed ‘too high’ in the presence of sufficient androgens.

Nobody has found this. This is like me saying nobody has found a unicorn yet you want me to prove it. How do you prove something that doesn’t exist?

If you believe that there IS concern for too high level of estradiol, in the presence of sufficient androgens (which I disagree on) then provide evidence to support a certain level or higher being detrimental to health. I know you can’t do this because none exist. It has never been found.

So to continue to tell me that there is a level deemed too high for some men, and not being able to provide any evidence to support your claim, when I flat out demonstrate that there is an ABSENCE of evidence in the medical literature to support that, only to demand that I provide “evidence for an absence of evidence”… is a logical fallacy. It can’t be done.

There is no evidence for high levels causing harm. There is only evidence of estradiol providing benefits in the presence of sufficient androgens.

If you have high levels of estradiol and an androgen deficiency, this is not ‘high e2 issues’. This is ‘androgen deficiency issues’.

I honestly do not know how I can possibly be more clear here.

I have provided a ton of papers regarding the benefits of estradiol. There is no paper demonstrating a high limit that exists because none has ever been found.

YOU claim to have studies that demonstrate harm with estradiol. I’ve asked a dozen times for these papers and you send me to Google. I didn’t ask you to search for the papers I sent you. I sent them straight to you. If you have the studies you claim, send them to me. At the very least give me the TITLE of the paper so I can find it and read it.

Again, and again, and again… you have provided ZERO evidence for anything in return.

151

In one of your studies they gave men 2.5mg ED of letrozole. DB this doesn’t prove anything. Your studies are garbage and the fact that you’re extrapolating on this kind of stuff and applying to TRT is a joke. Earlier you stated these were studies on people with healthy levels. WTH are you talking about? Those subjects Aromatase and Estrogen is slammed so hard into the ground they probably killed themselves 1/3 the way through the experiment.

These studies are what you’ve been basing your Dogma on??? These are your scrolls. GTFO bro

1 Like
152

No… you see, you’re the joke because you can’t provide me with a single paper. Not even one. Even after I’ve requested just one, over a dozen times, with every reply you are still incapable of providing anything.

I can send you another 100 papers, you won’t read them, claim they’re stupid, yet ask me to provide evidence for something that has never been found, yet remain under the delusion that high levels are harmful, even though you have no evidence to support your belief.

This conversation is over. You are not worth my time.

153

https://www.health.harvard.edu/newsletter_article/Men_and_depression

Signs and Symptoms of High Estrogen: Diagnosis, Treatment, and More.

I could post hundreds more that are way more credible than your crap. You managed to get me off my lazy ass. Shoot, I could post thousands more. But whats the point. This is common knowledge. The Earth is round too! Did you know that?

I truly hope people read those studies you posted. Don’t delete that post. Keep it there so people can read it and see why you feel qualified to dish out medical advice.

154

Good Lord I just read through the entire paper “Estradiol as a Male Hormone”. Nowhere in there does it say that E2 can go as high as infinity without consequence. It does not support elevating it to supraphysiological levels, or convey “the more the better”. This is blowing my mind that this is your Dianetics. Unreal.

2 Likes
155

The mindblowing is you failing to understand what I’ve been repeating over and over. THAT is mindblowing. Here is a copy/paste from above because I won’t waste any more time on you. CORRECT: Nowhere does it say that high levels of E2 do anything because they never found any level deemed too HIGH.

Read this over and over and over until you understand it:

I don’t know how else I can be more clear:

In all the studies of estradiol, in the last 80 years of study, nobody has ever found an amount deemed ‘too high’ in the presence of sufficient androgens.

Nobody has found this. This is like me saying nobody has found a unicorn yet you want me to prove it. How do you prove something that doesn’t exist?

If you believe that there IS concern for too high level of estradiol, in the presence of sufficient androgens (which I disagree on) then provide evidence to support a certain level or higher being detrimental to health. I know you can’t do this because none exist. It has never been found.

So to continue to tell me that there is a level deemed too high for some men, and not being able to provide any evidence to support your claim, when I flat out demonstrate that there is an ABSENCE of evidence in the medical literature to support that, only to demand that I provide “evidence for an absence of evidence”… is a logical fallacy. It can’t be done.

There is no evidence for high levels causing harm. There is only evidence of estradiol providing benefits in the presence of sufficient androgens.

If you have high levels of estradiol and an androgen deficiency, this is not ‘high e2 issues’. This is ‘androgen deficiency issues’.

I honestly do not know how I can possibly be more clear here.

I have provided a ton of papers regarding the benefits of estradiol. There is no paper demonstrating a high limit that exists because none has ever been found.

YOU claim to have studies that demonstrate harm with estradiol. I’ve asked a dozen times for these papers and you send me to Google. I didn’t ask you to search for the papers I sent you. I sent them straight to you. If you have the studies you claim, send them to me. At the very least give me the TITLE of the paper so I can find it and read it.

Again, and again, and again… you have provided ZERO evidence for anything in return.

156

Danny and his FB group…a lot of it is a joke. I was a member until they kicked me out because there was a debate about mask wearing and Covid and I quoted a tweet from Arnold Schwarzenegger, “This is 100% the right move. This will help us beat this terrible virus. The science is unanimous - if we all wear masks, we slow down the spread and can reopen safely. It’s not a political issue. Anyone making it a political issue is an absolute moron who can’t read.”

Apparently the “fact based” Facebook group got its feelings hurt.

157

This is nonsense. We have ZERO covid related posts in our group. It isn’t discussed. You must be referring to another group. We sure as hell wouldn’t ban anyone for or against masks. All decisions go through me, the admin, so I would be aware if this actually took place. It didn’t.

I’d be happy to look up your name in the ‘banned list’ to see if it is actually there and see the actual reason why you were banned, if you were.

P.S. The science is NOT unanimous.

158

Bro just leave. You can read the links I provided and check the sources and everything, or not. I don’t really care. I’d be embarressed if I acted like you. You just dumped your load like it was going to blow peoples minds and it just made you look like an idiot. I encourage everyone to read the studies Danny posted and apply the same level of scrutiny to them that Danny does to you. He’s an absolute joke.

3 Likes
159

medicalnewstoday. com as your source.

Yup… very credible.

References? There are no references. It’s an opinion piece.

A harvard link on depression that we can’t read unless we sign up.

But I’m the idiot? Hahahahahahahahahaha

I’ll leave all this here for anyone with a shred of intellect to go through. There is a reason why there has been a mass exodus of guys from here to our group. THIS is why.

1 Like
160

At least my sources back up what I’m saying. Your sources don’t even support you but your too stubborn to even know it hahaha

Go ahead and run away Danny. Take your ball and go home. Earlier you said you were leaving but you’re still here for some reason

4 Likes
161

Dr. Steven Devos, the Lifting Dermatologist, posted a cartoon about people who wear masks. You can’t control what he posts so to say there are “ZERO covid related posts” is straight up false.

There definitely was some good information in the group but to pick and choose science in order to fit your POV makes you lose all credibility.

2 Likes
162

Find my email address in my profile, email me your name… I want to go see this for myself. No idea how anyone would get banned over mask bs.

163

Sure thing keyboard warrior.