So after a long discussion with my Dr at the weekend we discussed my problems with unable to get dialled in and my issues with feeling well on TRT, we discussed the possibility of coming off but before we go that route we are going to first trial daily dosing of Testosterone Cypionate SUBQ for 8 weeks then if no improvement last option before quitting will be compounded cream.
So I am about 6 days into SUBQ daily of 12.5mg and first of all I will say how easy and hassle free it is to inject, the Cyp is so smooth and water like compared to the Enanthate which was in castor oil.
I have noticed though that I have felt very flat, even more tired and weak, is this normal for SUBQ? Is it a matter of sticking it out and letting it build up before making a real judgement or is it better to go shallow IM?
My Dr said that SUBQ is slower released and thus will lead to lower peaks and troughs but also reduced aromatisation to E2 which you get with IM.
You will see from my previous posts that I am low SHBG of 14 nmol/L, is daily dosing really essential or has the potential to be a game changer?
This will be my last post hopefully for a while, I am going to try to either stick to SUBQ or shallow IM and stick to this and get away from forums etc and try to really let things take course, I need to stop constant changes, I understand that my body wants homeostasis and it will never achieve that if I am constantly changing doses, frequencies etc, I have learnt the hard way and at this point Iām even willing to push through some dips and tiredness if I know that things will get better and level out.
Basically how he described it to me was injecting SUBQ the medication has to go through a few processes and then the capillaries before it is then transferred to the liver and the ester cleaved etc, so basically it is a slower more gradual process.
Muscle is a lot more vascular and follows a slightly different/faster process, also muscle has a lot more capillaries which also quickens the process, thus more of the medication will reach the liver in one go and more quickly which will result in slightly more conversion to E2.
More and more I see posts like this. āI switched to SQ and donāt feel the sameā yet everyone (well, a lot of ppl) keep advocating for it.
The ester controls the absorption (along with the carrier oil, a bit). Inject IM and let the meds work as they were designed to do. If you want a slower release, use a longer ester and a thicker oil.
And yes a I know, there are a couple of studies floating around in FTM patients showing that eventually they reached the same hormone levels as IM, but they injected on a different schedule than the other group and no one asked them how they felt during that process lol.
Yes, but I asked for data as in studies. Every doc or Tom, Dick, and Harry has their own opinion of how it works or doesnāt. Coincidentally there was a study I believe by Boston Med that tried to examine IM vs Sub Q but only 2 participants competed the trial. Inwill try to find it as it looked so promising but alas ended up unsuccessful.