More Labs and Back to Not Feeling Good Again

I some how have gotten away from the sweet spot. For the last few months my BP has been high 160/90 ish anxiety through the roof and depression like I haven’t felt in a long time. I finally went to see the doc and did labs. I’m wondering if my testosterone levels are too high now? Or do I need to just get on antidepressants?

ALBUMIN,SERUM
4.4 g/dL (3.6-5.1 ) completed
SEX HORMONE BINDING GLOBULIN
18 nmol/L (10-50 ) completed
TESTOSTERONE, FREE
341.7 pg/mL (46.0-224)
TESTOSTERONE, TOTAL, LC/MS/MS
1251 ng/dL (250-1100 )
TESTOSTERONE,BIOAVAILABLE
687.9 ng/dL (110.0-575)
Estradiol
31 pg/mL (< OR = 39 )
PSA
1.0 ng/mL (< OR = 4.0
HEMATOCRIT
48.2 % (38.5-50.0 )

I sub Q inject .35mg Testosterone Cypionate M,W,F
HCG 350iu M,W,F
Anastrozole 1/3 of a 1mg pill M,W,F I melt these in vodka and use a syringe to dose
Blood test was taken Thursday morning. I’m not at a good place mentally and my life has really never been better. From the outside I would say I have just about everything I’ve ever want. On the inside I’m a mess. Sex drive is great no ED relationship is good with my wife. My brain is just not happy anymore. Any advice would be greatly appreciated.

Your T levels are high out of range. Id suggest dropping T dose by 35% to lower free T and total T to mid/high ranges. I get higher BP too when my numbers look like yours. Remember lower T will likely mean lower E, so youll need to ai reduction as well.

Too much testosterone can play havoc on other systems, I get high blood pressure when E2 is too high, but I could imagine it could be something else out of whack also causing an imbalance from levels being too high.

Your lower SHBG which means you have more free testosterone than a guy with higher SHBG, some low SHBG men need E2 closer to their SHBG numbers. We have the same SHBG levels and liver is healthy and I can’t tolerate levels in the high normal range.

Liver clearance of E2 could also be a factor, you would then need E2 at a lower number than a guy who clears out E2 more efficiently.

Thanks for the response! I’m definitely going to lower my dose. Thinking about just cutting everything by 1/3. Not sure if this will cause more of an imbalance but hopefully in time I’ll level out again. E2 has been a tough thing in the past for me. I’ve been high and low both are a nightmare. If I don’t stay in the high 20s I have terrible anxiety and panic attacks if I get into the high 30s my nips burn and I have zero sex drive along with very strong emotions. I can remember testing in the mid 700s and I felt much better. Hopefully that’s all it is. Thanks again.

You’re going to feel like crap for a little while cutting the dosage by a lot, recheck levels in 6 weeks.

Many would find find less E2 would improve libido, but your complaint seems broader than that.

This conversation really needs info re thyroid and iodine. Your oral body temperatures could easily resolve what is going on if thyroid function related.

BP is serious. Meds for that? Prior history. Hematocrit [HTC] does not seem to be a cause. Do you feel or look bloated? Headaches? Anxiety can be a strong contributing factor. Any change to urination or urges to void?

I’ve dosed iodine and selenium per your instructions and I definitely increased my morning temperature but that was some time ago. I didn’t have high BP a few months ago this is all new to me. Honestly if my sex drive was any higher it would be annoying. I’m 41 married with 2 kids. I’m not bloated, honestly for as much as I’ve been working and not sleeping and skipping the gym I look really good. I can’t feel like crap. My job is very physical and can be extremely dangerous. Should I taper off my dose slower? I have a lot more labs I can post just ran out of time. My white blood cell count was low. Scary but hopefully just a fluke. No idea why this would be also cholesterol was high. I’ve never had high cholesterol. I’ll give exact numbers ASAP. Thanks again everyone.

White BLOOD CELL COUNT
2.8 Thousand/uL (3.8-10.8 )

LDL 119 mg/dL_(calc)
TSH 0.83 mIU/L (0.40-4.50 )
Non HDL was 141 <130

Just putting all this thought into this is stressing me out completely today. I’ve never felt so much stress/anxiety for such normal activities like work or family life. I sleep for 8 hours on average but can still nap everyday. I can’t remember the last time I woke up rested. I really just need to get back to the sweet spot and fell like myself again.