How many long term studies are there for TRT, particularly Test Cyp injections? Anything out there taking it late 30’s through their 50’s or 60’s.
Thanks!
Don’t think they’re are really.
Let’s be honest with our selves, priorities change as we age, I’m keen to have strong libido and athletic performance at age 52 but pretty sure that won’t be the case in even 20 yrs time…
Really can’t see myself doing TRT until life’s end (assuming old age) it’s just not feasible is it?
I would argue that priorities change mostly based on brain chemistry changes as we age, not experience.
A lot of people think they’re getting wiser as they get older, and will often say things like “as I got older I realized there’s more to life than sex”.
But it’s bullshit. It’s not wisdom, it’s hormonal degradation and loss of appetite for life. The same guy on a fine tuned TRT/GH/etc…protocol would suddenly go right back to thinking that sex is everything, the same exact way it felt when he was 16yo.
I think we often ascribe to experience and wisdom changes in personality that are in reality almost 100% a reflection of chemical and physiological changes as we age. A lot of people don’t want to believe that because they find the implications depressing, but it’s the truth.
As far as still being on TRT in my 70’s, 80’s, etc…I think it’ll feel even more important to me to have an optimal hormonal balance then than it does now.
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I would definitely aspire to that too 
Are there any 70 - 80yr olds on here that could share their experiences on this? Be great to hear about it
Not that I’ve seen, and I’ve seen that question asked a few times. I vaguely remember maybe @highpull mentioning a patient who’s in his 80’s, but I could be completely wrong.
https://academic.oup.com/jcem/article/82/11/3793/2866086
“In conclusion, testosterone replacement therapy appears to be well tolerated by over 84% of the subjects. Long term testosterone replacement to date appears to be a safe and effective means of treating hypogonadal elderly males, provided that frequent follow-up blood tests and examinations are performed.”
I think the one caveat is that they prolly aren’t keeping these study subjects on TT of 900-1000+ng like many guys like to run. So that 84% may be lower for that group
I am also unaware of any long term studies and I am not optimistic about the potential for one. I do have guys in their 50s and 60s who have been on testosterone for 20-30 years. All were previous AAS/PED users. I’m pretty sure every one of them used underground sources for most of those years.
None of the guys in their 80s have been on TRT for over ten years.
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Having read that JCEM article I’m quite encouraged by the possibility that TRT can be done safely into old age and probably has more benefits than drawbacks.
As Swoops alluded to, the key in older age is not to run those T levels too high and continue with careful monitoring👍
One of the points made in the article I found helpful was that yes, frequent monitoring is a bit inconvenient but it does have the potential to show up serious health issues early that otherwise would have been missed in the general population not on therapy.
We’re pioneering this level of maintenance. TRT is new age stuff this decade. Next decade will have 70 and 80 yr olds who have been on TRT. Excel male has a lot more guys in their 60-70s. TRT is life and for life.
I am 72. Been on TRT for two years. Improvement in energy and attitude was immediate. BUT, what I believe to be a total systemic/hormonal realignment has continued monthly, with dramatic results: body recomp, youthful attitude and energy, libido, potency, etc. all continue to improve.
I believe TRT, at least for me, is a long term proposition. For example, it took around 16 months to to get dialed in.
I stabilized at:
110 mg TC a week
600 units HCG a week
The above injected in 3 divided doses a week.
5 mg tadalafil daily (took months to fully produce improvement, then, wow)
The above is NOT a recommendation, as I am sure that what is correct for one is not correct for all.
Daily tadalafil produces more than just erectile improvement…I got the other benefits people have reported, but it took TIME. I initially stopped tadalafil because I saw only very modest initial improvement. Now, I would not consider removing it, at all.
Note that I have also been doing daily mental/spiritual exercises and got major elements of my life and relationships straightened out.
I believe that stress, conflict, and a compromised life can fight with the benefits that medicine could otherwise provide.
I believe it’s a package, not just all mental/emotional/spiritual and not just all material/physical/chemical. It’s interactive.
BTW, many others have remarked on the improvements they have seen in me.
Thanks to all here on this site for all the info you shared. YOU, particularity the regular posters, were my source of info, guidance, encouragement and support. Thank you.
Addition: I also built up to 90 minutes, five days a week, of walking up a hill, about 600 feet vertical gain, then back down… got to the point where I could intermittently jog up the hill. I was shocked. Lost 40 pounds, getting down to 195 lbs at 6 feet tall.
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Second addition. The hill is 600’ high. The vertical gain is likely two or three times that, due to ups and downs.
This is great stuff! Question- are you using generic tadalifill?
One thing I will say one very big reason I’m considering quitting is my short fixed these days. It’s been off the charts. I take .2 at 200mg/ml.
I’ve also been under a lot of stress lately as I’m taking on a lot at work, building a house and moving in with the in-laws did a month or two. I’m taking Xanex about everyday the last month along with THC gummies to help me sleep. It’s working but my attitude side effects may be causing the issue too. It’s just I know TRT can shorten your tolerance and mine is short these days.
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Not to mention I worry about heart issues with it rubbing in my family and I know there is risk stab TRT and heart health.
Yes, re generic tafalifil.
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Understood. You might want to add additional stress reduction:
The number one, “do or die”, a) Google and read up on “anti-social personalities” then, b) examine the people you are connected to, are any of them anti-social personalities? C. If so, figure out how not to be the effect of them … if any question, do whatever you have to do to sever all connection to them.
It is almost impossible to have health and a good life if connected to a true psychopath…and about 2% of the population are psychopaths/anti-social persons. That’s a big percentage, for such a highly toxic type of person.
#2. Add some non-chemical stress reduction … walking/ jogging /running, meditation, or whatever.