Long Term Effects of 500mg Test/Week and What is "Long"?

I hear people many times say “long term effects” but how to specify what range does the “long” mean ? 1 year,5,10 ?. I know few guys who have been on 500/week for like 3-4 years, no problems at all. But since every one is different, how fast things can go bad and how bad you can get things with 500test/week ? for a 3-4 month period, i think not realy bad, but lets say all years around with 500 ?

3-4 years… men live 78 years on average. I’ll look up some studies and report back on long term consequences of Supra physiological doses. Unless @anon18050987 has some already.

I think this is another good study to look at to somewhat quantify the effects of long term high dose use.

The median dose and time was 675 mg of testosterone (all dosages of AAS were equated to an amount of testosterone), and 468 weeks of use. So this is pretty high levels of use.

Changes in heart were observed. Here is a graph of LV ejection fraction comparing users and non-users (all weight trainers though).

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