LABS - High E2 Normal TT During Test Cycle

Hey everyone, new member but long time lurker before it went private. I’m 30, 6’ tall, 220 pounds at around 14% and I’ve been on TRT (150mg/wk ED injections) for about 7 years and haven’t done a cycle in 8 years or so. I got labs done 14 weeks into my 16 week blast of 300mg test cyp a week and I’m puzzled… here are some numbers during TRT compared to my blast:

TRT -
Total Testosterone - 930ng/dl - 240-980ng/dl
Free Testosterone (dialysis) - 338pg/ml - 35-155pg/ml
E2 ultra sensitive - 46pg/ml - 12-50pg/ml
SHBG - 8nmol - range 14-55

300mg blast (same ranges as above) -
Total testosterone - 965ng/dl
Free testosterone - 386.9pg/ml
E2 ultra sensitive - 115pg/ml
SHBG - 3.8nmol

After a hiatus of not working out for a few years I was able to go from 193-220 on this blast (a lot of muscle memory returning) with maybe gaining 1% bodyfat but mostly only noticed in my stomach while I got leaner everywhere else…

My question is, why is my total test and free test similar on 300mg as it is during my 150mg TRT dose with the same product? Is my body literally converting all that excess test straight into estrogen? I’ve made great gains but can’t imagine my levels being so similar to my trt levels this entire time during my blast. I never added arimidex as I had no sides whatsoever other than minor bloat in my stomach during this blast. No puffy nipples, no sexual dysfunction, no acne etc.

I just took .25mg arimidex and will take another .25mg in 3.5 days before I get labs redone in 10 days to see if that allows for more test to be active. I expected my TT to be around at least 1500 on 300mg a week.

Couple things… your SHBG is low and got even lower. The timing of your labs probably has something to do with it too since your blast wasn’t very high in dosage. For example if you take 150mg and test in 72 hours versus 300mg in 6-7 days you results could appear quite similar. Especially with a change in SHBG.

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That makes sense. I was just stumped because since I inject every day and always have my labs done 24 hours after my last injection I figured my total test would have been higher.

Well if that’s the case then my theory isn’t valid. Was the T from the same source?

Same source from my doctor that I’ve used for years. I contacted him and he said only possibility he can think of is that after a certain dosage without an AI my e2 gets to the point where it “overpowers” the test I inject and ends up converting nearly all of it to e2 because of my low SHBG. He said with all my prior labs he would guess my TT would be in the 1700-1900 range on trough since I do ED injections. Pretty disappointed that I went about 15 weeks having this issue, although I never felt bad by any means and never really felt “on” like I have in the past.

I guess new labs after taking .25mg arimidex a couple times should prove if that point is valid and I can up those numbers. If not I guess I got a bad batch from my local pharmacy. Still wouldn’t explain my ridiculous e2 numbers though.