Insufflation (Snorting) Dbol - Trip Report

Pharma TRT
61

[quote]Isochroma wrote:
5F-AKB48[/quote]

And this confirms a couple comments about this sounding similar to illicit drug trip reports. Let me guess OP, you keep pretty up to date on the research chemical/designer drug world? I don’t have any problem with that personally, but what you’re doing is already pretty far out there, and it would only loosely be considered TRT to the vast majority of people. You talking about recreational drugs, using terms almost exclusively used by those in the recreational drug scene, and writing this in such a way that someone would describe their acid trip does nothing but discounts any valid information that you might actually have.

62

Yes, I am involved in the research chemical scene and was involved in getting Sunifiram and Unifiram to market - a bit indirectly because I pushed the data out onto forums and dug up Chinese chemco suppliers. About six months later the first company started selling Sunfiram. I will never know for sure how important my work was or was not but I’m very glad it became available!

It was a lifesaver for me and continues to be an important part of my regime though its importance has diminished with androgen repletion.

My next project is researching Xenoandrogens - not the evil ones like Tributyltin but the ones designed to replace AAS. They have milder effects, come on much slower and - by one forum report - it seems that due to molecular differences from current androgens they do not result is as much or any downregulation of natural Testosterone production!

It would be the most amazing revolution in all of endocrinology if a molecule could be invented that would act to agonize androgen receptors but did not activate the HPTA negative-feedback loop’s sense-system. If this could be accomplished then it would be possible to simply ‘add’ androgenicity to the system without downregulation of internal production. Even better, these molecules are as of now still unregulated and so create no legal risks.

However - like Sunifiram and Unifiram - the Xenoandrogens are research chemicals. That means we have no idea what they will do to human health after long-term use. I have not seen a single report of side effects on any forum yet which is encouraging.

It might be time to give up forever on the normal Testosterone carbon-skeleton frame and instead move to totally different molecular architectures in order to circumvent the many problems caused by such agents. The progress made in nootropics is very encouraging - molecules with very different chemical structures were found to produce similar effects as quite old, existing frames such as the pyrrolidine-based racetams. Sunifiram and Unifiram are based on the Piperazine backbone instead and have much higher peak activity and potency.

I am going to start examining various Xenoandrogens to get a feeling for how their shape works and then I will contact my Chinese suppliers and have them start custom-synthesizing some test molecules which may have activity. The only problem is arranging a way to safely test them without too much risk. The potential financial and patent rewards for success in this field can be measured in billions of dollars - at least until tyrannical governments ban them.

In between those times exists the gigaprofit window :slight_smile: Due to increasing Xenoestrogen contamination and concomittant population-wide Testosterone decline in men, I anticipate there will be a vast new market-segment for androgen replacement in the near future if not today. Thanks also to physicians and the sorry state of HRT practice today, I also predict a massive wave of abandoned victims who will be absolutely desperate for a solution as they slowly rot and die of the numerous diseases and dysfunctions induced by hypogonadism.

I guarantee a massive wave of abandoned male victims of Xenoestrogenic destruction who will have no relief - like myself - and will pay anything for a functional solution to their worsening symptoms. Lives gone to hell have a tendency to create such desperation and by the time the main wave comes I want to have the solutions for sale. Those who are positioned to make hay while the sun shines will make hay aplenty in this infant and highly promising field.

I owe the bodybuilding field and its population of enthusiasts a deep thanks for keeping the androgen supply available for their own purposes. Thanks to that availability, there is an entire well-funded industry set up to supply androgens for their purposes. Mine are different but their solutions in smaller dose form work reasonably well to solve most of the problems the chemical plants have been creating via Xenoestrogenic pollution.

It’s rather ironic that the same industries guilty of creating this disaster may be our only short-term hope to reverse some of its worst effects on the male frame. Over the long-term all these Xenoestrogens and the toxic Xenoandrogens like Tributyltin must be banned. If these chemicals are not banned now they will keep accumulating until their level reaches a degree that all males will be sterilized and humanity will end.

The problem is that most of the Xenoestrogens are rather stable, fat-soluble molecules that both accumulate and biomagnify up the food-chain just like PCBs and Dioxin. In a hundred more years the accumulated levels will become really problematic for most men. In fact they already are, with 25%-37% of American men suffering from Xenoestrogen-induced Metabolic Syndrome which is killing them quickly by heart attacks, diabetes and other unnaturally-induced medical conditions. Just imagine how bad it will get when Xenoestrogen concentrations double, triple, quadruple, quintuple?

It’s not a question of if but when - how many more years for the next doubling of Xenoestrogenic contamination and its accompanying cut in average Testosterone levels?

My most perfect dream is a hyperpotent, non-HPTA activating androgen molecule that’s reasonably stable. Dissolved in edible ink inside a normal bubble-jet cartridge tank. Then the doses are printed out onto paper or other media like LSD. Printing allows extremely precise, computer-controlled dose deposition.

In fact even today anyone can put a bioactive molecule that’s water-soluble into their bubblejet cartidge and print it out in nice squares or whatever shape onto paper to very cheaply and rapidly produce sheet after sheet of precisely-controlled doses. I was shocked to find that only one other person thought of the idea and patented it.

63

ISO, you are clearly a very intelligent and motivated individual. That being said I believe that the information you post here is potentially dangerous to the countless men and women who come to this forum for scientific based guidance. I sincerely hope that anyone reading this personal manifesto is doing so subjectively.

64

It’s always good to get feedback.

Regarding the studies on Xenoestrogens, I let those speak for themselves and provide the links. As for my own theories, you can tell they’re mine because I don’t link them to anything - they’re my own concepts. Everyone should realize that while the topic of this thread is the new nasal ROA, the molecule Dbol is very old - 53 years as of today - and is now very well-understood with known positive and negative effects.

I could never tolerate Dbol doses that bodybuilders use - my body is just too sensitive to the side effects. So I consider my use - despite the novel nasal ROA - very safe since it’s so small and would never recommend anything over 10mg/day for anyone. Even as is, there are two side effects to the oral 7mg that annoy me and they resumed with the oral dosing I resumed yesterday - constant liquid stool which I’ve gotten used to :frowning: and the sleepy-tiredness which has been showing up around 10:30p.

Oh, I was thinking today about trying the printer method to print out squares of Dbol onto paper. Since Dbol is fat-soluble I would dissolve it in Isopropyl alcohol and leave a bit of ink in the tank so that the squares can be seen. The problem is that it would be impossible to tell how much Dbol was actually in each square unless one were to print out the entire tankload and divide by the number of squares.

I also came up with another idea for adhesive patches. It uses the same bubblejet print method but there’s an added foodsafe chemical that turns gummy & sticky when the solvent evaporates. So after the squares are printed out onto perforated paper they turn sticky as the solvent evaporates. When the paper’s completely dry you just tear off a square and stick it onto the skin as a patch or under the tongue for sublingual. The gummy stuff keeps the material from dissolving much in the mouth so it helps to keep it directed into the bed of blood microvessels under the tongue.

Nobody has that one patented yet. I wonder if it would work.

Today was the second day of combined 7mg oral + 7mg IN. Worked very well and body did not feel like I took any more than the usual 7mg but mind worked far better than the few days of 7mg IN only. It seems that when optimal androgen receptor activation exists in both mind and body, the two work much better than if one is lagging. It’s reasonable and logical so I can believe it.

Still, I need to switch to something better. The IN dose for cognitive function can easily be substituted for natural Testosterone or any of the non-methylated synthetics because it absorbs directly. The problem is the oral dose used to replenish the body. There’s got to be a less-toxic oral androgen than Dbol but I haven’t quite figured out which one.

There’s one more very important condition too - it applies only to those using androgens to replenish deficient Testosterone. Because Estradiol is made from Testosterone, a Testosterone deficiency implies and Estradiol deficiency too. So the androgen used to replenish must also convert via Aromatase to Estradiol at least a bit. Dbol seems to do it well enough but unfortunately most of the newer androgens were designed to prevent aromatization.

Those ‘dry’ androgens are incomplete so one would have to take Estradiol with them. From my research Estradiol is orally active so that shouldn’t be a problem but I might be wrong. I’m trying to build a list of ‘wet’ orally-active androgens as a start but I’m not sure this will be the best route. It’s like being a cook, trying to add the two ingredients in the correct proportion to make a recipe.

65

[quote]Isochroma wrote:
My next project is researching Xenoandrogens - not the evil ones like Tributyltin but the ones designed to replace AAS. They have milder effects, come on much slower and - by one forum report - it seems that due to molecular differences from current androgens they do not result is as much or any downregulation of natural Testosterone production![/quote]

Check out some of the SARMS that are out now if you haven’t already. Seems like the same idea as what you’re talking about. I don’t know about TRT doses, but I know at least with bodybuilding doses, there is still supression despite the difference from testosterone.

66

Thanks for the suggestion!

And wow! Today marks the 30th day of my Dianabol ART program - dosing began on on August 7th, 2013 - the very day my ten grams of 99% pure Dianabol arrived by Express mail directly from the Chinese chemical company that manufactured it. After a month I can report results whose accuracy is far better than after only a few weeks.

It also marks the first week of using dual-mode administration: daily doses of 7mg orally and 7mg intranasally taken about a half-hour after awakening.

If I had thought that the first oral-only regime was solving problems - which it was - I was as wrong as the Sun rising in the West.

Combined administration has produced results for both mind and body which have far exceeded any results obtained in those first three weeks. In the last week both physical and mental productivity are through the roof - the washroom cupboards are now cleaned as of this morning, a chore waiting since April to be done. Lights are changed to a whole new system, etc.

Confidence is through the roof and I’m planning new projects at a dizzying pace and implementing them with a dedication and level of organization which I have not seen since before Summer 2008 when I started on Piracetam.

Now for the differences between my customized Dianabol program compared to Testosterone shots or patches in point form:

Positive: The benefits compared to Testosterone

  1. I have kept about 80% of my natural production because - even if Dianabol were as suppressive as Testosterone molecule-for-molecule, both its anabolic and its cognition-restoring effects are many times more potent on a milligram basis. I’ve heard numbers as high as 8x relative to Testosterone. The dose of Testosterone required to provide equal anabolic and I presume cognitive effects would be many times higher and thus far more suppressive of my natural production. Having kept such a high level of my own Testosterone production also means I keep my sperm production in case I want to have a kid. Kids are not for me but for many other guys - especially the ever-younger men falling prey to toxin-induced low-Testosterone - fertility is important.

  2. I don’t have painful memories and scars from weekly Testosterone injections.

  3. Androgen is loaded during the correct phase of my circadian rhythm so it functions optimally with the least possible suppression of my existing Testosterone production. The HPTA axis has its ‘eyes’ mostly closed during the brief 1-hour window after a man wakes up, so it hardly ‘sees’ the extra androgenicity I’m adding. Males are genetically evolved to have a large spike of Testosterone release in the early morning - not to have a high level throughout the day as a depot injection or patch would produce. If the only option was a needle then injections would have to be daily and taken early each morning.

  4. My hair is still as it always was with not a trace of recession or increased fallout.

  5. Chest is of course still flat as a board - I can’t imagine why filling unoccupied androgen receptors with just enough Dianabol to make up for my Testosterone deficiency would do anything else. What little I take is just barely enough to fill them with almost nothing left over in circulation to aromatize to methyl-Estradiol, which even though it has higher affinity for activating a man’s breast-cells is still so low that there won’t ever be a problem. My body is naturally thin to begin with and I’ve always been dangerously underweight with my current weight at 138lbs on a 6’2" frame - a BMI of 17.7 (underweight). At such a low BMI I have precious few fat cells - they are much more efficient converters of both Testosterone and Dianabol into their corresponding Estradiolic sister molecules.

  6. Muscles are no longer constanty painful from the slightest exercise or even heavy exercise so it’s become a plesure to use them fully each day for more than I would have dared a month ago or five years ago. They’ve bulked up a bit too and at the low 7mg dose with virtually no aromatization to methyl-Estradiol the new growth is tight. I feel the tightness every time I walk because as a lifetime cyclist my main muscle development has always been the in the legs. It’s great feeling that was unexpected - they want to be stretched and exercised. It’s strange, like they have minds of their own.

  7. Cognition. The place where as much benefit accrued as the rest of my body combined. Intellectual output has shot through the roof and increases daily without significant symptoms of excess such as restlessness, anger, tension, etc. Rather, mood is consistently upbeat and incredibly positive every day with a trend of daily improvement that has not stopped since starting the intranasal component a week ago with minor improvements seen since the beginning of oral use on August 7th.

Neutral: The effects which would likely be the same with equivalent Testosterone supplementation:

  1. Appetite. Before starting the program I had poor appetite and stomach stayed ‘full’ for a long time with no new hunger for the entire day until dinner from a single light breakfast - exercise or not. Now I can’t eat enough - exercise or not. A couple hours after a massive breakfast my stomach is literally hurting - ravenously hungry for more food. My shelves are emptying of food at a frightening pace and I’ve had to increase my food budget for next month.

  2. Weight. My DNA programs my body to BURN BABY BURN - literally. I wish I was kidding. Every last calorie that I can absorb is burned away faster than I can eat more. It’s always been this way whether I sit still or cycle miles on hilly roads. Now it’s even ‘worse’ if that could be imagined. The new Dianbol-induced hot metabolic fire which roars from morning until late afternoon is burning away those last fat cells even faster along with every single calorie I can dump in. It’s vicious and unforgiving and I feel like I’m running a race against Death itself to inject enough calories. Yet despite this vastly accelerated metabolism the Dianabol’s anabolic function is just powerful enough to hold my existing muscle mass steady. Just barely.

Negative: Now for what I likely would have experienced if the doctor had been ‘nice’ enough to give me the Testosterone shots I foolishly asked him for:

  1. Shutdown of natural Testosterone and sperm production to a high degree - many times more than the current program and possibly complete. By today - a month after beginning - the Testosterone would have devastated my natural production of both.

  2. Hair recession. The higher Testosterone dose required to produce equivalent anabolic and cognitive benfits would convert to vastly more DHT which would activate whatever hair-loss genes undoubtedly exist in my DNA.

  3. Painful weekly injection experiences and the memories of them in mind and muscle.

  4. Total dependency on the medicos for weekly injections - the $200/month patch is not covered under my medical plan and was never a financial option. Due to shutdown production I would be highly dependent on the doctors whose carelessness and frank lack of expertise have already pushed their reputation into the toilet in my eyes.

  5. Incorrect circadian timing. The weekly injections would produce a continuous Testosterone release or a single once-a-week spike - not only totally abnormal but maximally suppressive of my own production due to the haywire timing.

  6. Excessive androgenicity. Dianabol has an Anabolic:Androgenic ratio of at least 2:1 while Testosterone has a 1:1 ratio. I don’t want more facial hair, deeper voice or prostate growth. It doesn’t suit my personality. This is a personal choice that varies by individual. I do want the anabolic and cognitive benefits which Dianabol provides quite nicely as testing has shown. I have seen some increase in androgenicity of personality and other cognitive functions but little to none in other body systems. The increases so far are at the limit of what I will tolerate but in absolute level would be nearly unnoticeable to more typical men. I’m OK with the changes but no more please.

Overall, after a month it’s been a blazing success. Sex functions work as always if not even better and outputs in quantity and quality have not changed since before starting the program. Careful weekly testing has confirmed this.

The only disadvantage to my Dianabol program is that the Dianabol molecule itself with its bulky added Methyl group - CH3: lightweight at just over 15 Atomic Mass Units compared to Dianabol’s total of 300.441 - prevents enough from passing to the brain from general circulation to treat more than about 10% of the cognitive dysfunctions induced by low Testosterone. A human has a very selective blood-brain-barrier which does not allow most molecules to pass through - including charged species and large species. The charged and the large. Though more complex than the size of its holes - let’s just say that it has small pores. Small enough that Dianabol molecules mostly bounce off of it rather than passing through.

This means direct dosing to the brain in addition to systemic dosing is needed. Within the realm of reasonable things that can be done to accomplish this process - I decided based on the need to emulate my natural morning Testosterone spike that the only method which could deliver the needed dose in both amount and speed was intranasal administration. For some strange reason molecules cross into the brain very efficiently using this route of administration. I don’t know why but I know it works like nothing else with its own unique pharmacokinetics and pharmacodynamics.

The consequence of nasal administration is the need for pure Dianabol powder because crushing up pills would mean insufflation of large amounts of cutters, fillers, binders, etc. which would induce too much nasal drip reaction which would result in too little absorption and too much drip into the throat and from there the GI tract - sabotaging the purity and function of separate mind/body dosing.

A nasal patch similar to Trimel Corpration’s would likely work too but might have another problem: blood vessels inside the lower nose are more likely to move molecules into systemic circulation than those higher up in the nasal and sinus cavities - negating the original reason for intranasal administration which is fast, direct and exclusive brain delivery.

I intend this entire thread to be a guide for the coming wave of low-Testosterone victims. If my experiences with the disease process - it’s both a process of degeneration and a state of being - are any guide then they will be very glad to hear the good news and know that at least one safe, effective alternative treatment is available. This alternative to the official, standard Testosterone injection/patch works even better and is far cheaper, far more under the patient’s control and best yet is not subject to the yes-or-no of others - the medicos - who so often have no understanding or empathy for those who suffer by my experience.

That’s the only thing really hurting my heart right now and I think about it every day. I think about all the low-Testosterone victims that don’t have any relief. And I think about the others who have all-too-often partial, failed or otherwise dysoptimal relief using the standard medically-approved Testosterone replacement protocol of injections or patches. During my thousands of hours of online research - including hundreds of forum posts - I’ve seen their sad reports over and over again. Many of them. Too many of them.

Over the last hour today clouds which totally covered the sky in grey completely vanished, leaving a brilliant Sun shining in the vast, wide blue sky of my rural valley. Exactly like my life over the last month - not a trace of the darkness and grey remain.

It all burned away under the hot brilliance of a Dianabol star.

67

I’ve been following this thread from the start, most interesting I’ve read in awhile. It also has me thinking why the fuck didn’t this ever occur to me, dbol for trt? There are some draw backs but also some big fucking pluses and options it opens up.

Isochroma pm’s have been disabled here for a long time, can I pm you any other way email/other forum etc… super interested in this.

68

Thanks for the reply!

69

[quote]Isochroma wrote:
Thanks for the suggestion!

And wow! Today marks the 30th day of my Dianabol ART program - dosing began on on August 7th, 2013 - the very day my ten grams of 99% pure Dianabol arrived by Express mail directly from the Chinese chemical company that manufactured it. After a month I can report results whose accuracy is far better than after only a few weeks.

It also marks the first week of using dual-mode administration: daily doses of 7mg orally and 7mg intranasally taken about a half-hour after awakening.

If I had thought that the first oral-only regime was solving problems - which it was - I was as wrong as the Sun rising in the West.

Combined administration has produced results for both mind and body which have far exceeded any results obtained in those first three weeks. In the last week both physical and mental productivity are through the roof - the washroom cupboards are now cleaned as of this morning, a chore waiting since April to be done. Lights are changed to a whole new system, etc.

Confidence is through the roof and I’m planning new projects at a dizzying pace and implementing them with a dedication and level of organization which I have not seen since before Summer 2008 when I started on Piracetam.

Now for the differences between my customized Dianabol program compared to Testosterone shots or patches in point form:

Positive: The benefits compared to Testosterone

  1. I have kept about 80% of my natural production because - even if Dianabol were as suppressive as Testosterone molecule-for-molecule, both its anabolic and its cognition-restoring effects are many times more potent on a milligram basis. I’ve heard numbers as high as 8x relative to Testosterone. The dose of Testosterone required to provide equal anabolic and I presume cognitive effects would be many times higher and thus far more suppressive of my natural production. Having kept such a high level of my own Testosterone production also means I keep my sperm production in case I want to have a kid. Kids are not for me but for many other guys - especially the ever-younger men falling prey to toxin-induced low-Testosterone - fertility is important.

  2. I don’t have painful memories and scars from weekly Testosterone injections.

  3. Androgen is loaded during the correct phase of my circadian rhythm so it functions optimally with the least possible suppression of my existing Testosterone production. The HPTA axis has its ‘eyes’ mostly closed during the brief 1-hour window after a man wakes up, so it hardly ‘sees’ the extra androgenicity I’m adding. Males are genetically evolved to have a large spike of Testosterone release in the early morning - not to have a high level throughout the day as a depot injection or patch would produce. If the only option was a needle then injections would have to be daily and taken early each morning.

  4. My hair is still as it always was with not a trace of recession or increased fallout.

  5. Chest is of course still flat as a board - I can’t imagine why filling unoccupied androgen receptors with just enough Dianabol to make up for my Testosterone deficiency would do anything else. What little I take is just barely enough to fill them with almost nothing left over in circulation to aromatize to methyl-Estradiol, which even though it has higher affinity for activating a man’s breast-cells is still so low that there won’t ever be a problem. My body is naturally thin to begin with and I’ve always been dangerously underweight with my current weight at 138lbs on a 6’2" frame - a BMI of 17.7 (underweight). At such a low BMI I have precious few fat cells - they are much more efficient converters of both Testosterone and Dianabol into their corresponding Estradiolic sister molecules.

  6. Muscles are no longer constanty painful from the slightest exercise or even heavy exercise so it’s become a plesure to use them fully each day for more than I would have dared a month ago or five years ago. They’ve bulked up a bit too and at the low 7mg dose with virtually no aromatization to methyl-Estradiol the new growth is tight. I feel the tightness every time I walk because as a lifetime cyclist my main muscle development has always been the in the legs. It’s great feeling that was unexpected - they want to be stretched and exercised. It’s strange, like they have minds of their own.

  7. Cognition. The place where as much benefit accrued as the rest of my body combined. Intellectual output has shot through the roof and increases daily without significant symptoms of excess such as restlessness, anger, tension, etc. Rather, mood is consistently upbeat and incredibly positive every day with a trend of daily improvement that has not stopped since starting the intranasal component a week ago with minor improvements seen since the beginning of oral use on August 7th.

Neutral: The effects which would likely be the same with equivalent Testosterone supplementation:

  1. Appetite. Before starting the program I had poor appetite and stomach stayed ‘full’ for a long time with no new hunger for the entire day until dinner from a single light breakfast - exercise or not. Now I can’t eat enough - exercise or not. A couple hours after a massive breakfast my stomach is literally hurting - ravenously hungry for more food. My shelves are emptying of food at a frightening pace and I’ve had to increase my food budget for next month.

  2. Weight. My DNA programs my body to BURN BABY BURN - literally. I wish I was kidding. Every last calorie that I can absorb is burned away faster than I can eat more. It’s always been this way whether I sit still or cycle miles on hilly roads. Now it’s even ‘worse’ if that could be imagined. The new Dianbol-induced hot metabolic fire which roars from morning until late afternoon is burning away those last fat cells even faster along with every single calorie I can dump in. It’s vicious and unforgiving and I feel like I’m running a race against Death itself to inject enough calories. Yet despite this vastly accelerated metabolism the Dianabol’s anabolic function is just powerful enough to hold my existing muscle mass steady. Just barely.

Negative: Now for what I likely would have experienced if the doctor had been ‘nice’ enough to give me the Testosterone shots I foolishly asked him for:

  1. Shutdown of natural Testosterone and sperm production to a high degree - many times more than the current program and possibly complete. By today - a month after beginning - the Testosterone would have devastated my natural production of both.

  2. Hair recession. The higher Testosterone dose required to produce equivalent anabolic and cognitive benfits would convert to vastly more DHT which would activate whatever hair-loss genes undoubtedly exist in my DNA.

  3. Painful weekly injection experiences and the memories of them in mind and muscle.

  4. Total dependency on the medicos for weekly injections - the $200/month patch is not covered under my medical plan and was never a financial option. Due to shutdown production I would be highly dependent on the doctors whose carelessness and frank lack of expertise have already pushed their reputation into the toilet in my eyes.

  5. Incorrect circadian timing. The weekly injections would produce a continuous Testosterone release or a single once-a-week spike - not only totally abnormal but maximally suppressive of my own production due to the haywire timing.

  6. Excessive androgenicity. Dianabol has an Anabolic:Androgenic ratio of at least 2:1 while Testosterone has a 1:1 ratio. I don’t want more facial hair, deeper voice or prostate growth. It doesn’t suit my personality. This is a personal choice that varies by individual. I do want the anabolic and cognitive benefits which Dianabol provides quite nicely as testing has shown. I have seen some increase in androgenicity of personality and other cognitive functions but little to none in other body systems. The increases so far are at the limit of what I will tolerate but in absolute level would be nearly unnoticeable to more typical men. I’m OK with the changes but no more please.

Overall, after a month it’s been a blazing success. Sex functions work as always if not even better and outputs in quantity and quality have not changed since before starting the program. Careful weekly testing has confirmed this.

The only disadvantage to my Dianabol program is that the Dianabol molecule itself with its bulky added Methyl group - CH3: lightweight at just over 15 Atomic Mass Units compared to Dianabol’s total of 300.441 - prevents enough from passing to the brain from general circulation to treat more than about 10% of the cognitive dysfunctions induced by low Testosterone. A human has a very selective blood-brain-barrier which does not allow most molecules to pass through - including charged species and large species. The charged and the large. Though more complex than the size of its holes - let’s just say that it has small pores. Small enough that Dianabol molecules mostly bounce off of it rather than passing through.

This means direct dosing to the brain in addition to systemic dosing is needed. Within the realm of reasonable things that can be done to accomplish this process - I decided based on the need to emulate my natural morning Testosterone spike that the only method which could deliver the needed dose in both amount and speed was intranasal administration. For some strange reason molecules cross into the brain very efficiently using this route of administration. I don’t know why but I know it works like nothing else with its own unique pharmacokinetics and pharmacodynamics.

The consequence of nasal administration is the need for pure Dianabol powder because crushing up pills would mean insufflation of large amounts of cutters, fillers, binders, etc. which would induce too much nasal drip reaction which would result in too little absorption and too much drip into the throat and from there the GI tract - sabotaging the purity and function of separate mind/body dosing.

A nasal patch similar to Trimel Corpration’s would likely work too but might have another problem: blood vessels inside the lower nose are more likely to move molecules into systemic circulation than those higher up in the nasal and sinus cavities - negating the original reason for intranasal administration which is fast, direct and exclusive brain delivery.

I intend this entire thread to be a guide for the coming wave of low-Testosterone victims. If my experiences with the disease process - it’s both a process of degeneration and a state of being - are any guide then they will be very glad to hear the good news and know that at least one safe, effective alternative treatment is available. This alternative to the official, standard Testosterone injection/patch works even better and is far cheaper, far more under the patient’s control and best yet is not subject to the yes-or-no of others - the medicos - who so often have no understanding or empathy for those who suffer by my experience.

That’s the only thing really hurting my heart right now and I think about it every day. I think about all the low-Testosterone victims that don’t have any relief. And I think about the others who have all-too-often partial, failed or otherwise dysoptimal relief using the standard medically-approved Testosterone replacement protocol of injections or patches. During my thousands of hours of online research - including hundreds of forum posts - I’ve seen their sad reports over and over again. Many of them. Too many of them.

Over the last hour today clouds which totally covered the sky in grey completely vanished, leaving a brilliant Sun shining in the vast, wide blue sky of my rural valley. Exactly like my life over the last month - not a trace of the darkness and grey remain.

It all burned away under the hot brilliance of a Dianabol star.[/quote]

80% of your natural production huh. I didn’t see earlier the blood tests you must have had done to let you know this, mind posting your before bloods as well as your most recent?

Placebo effect is stronger than 7mg of dbol btw

70

[quote]protokultur wrote:
I’ve been following this thread from the start, most interesting I’ve read in awhile. It also has me thinking why the fuck didn’t this ever occur to me, dbol for trt? There are some draw backs but also some big fucking pluses and options it opens up.

Isochroma pm’s have been disabled here for a long time, can I pm you any other way email/other forum etc… super interested in this.[/quote]

Ditto! Thanks for the heads up protokultur, I sent Isochroma a PM and it didn’t show up. If you could, contact me as well.
Phileaux

71

Anybody else curious why KSman hasn’t chimed in?

72

I thought I have heard of it all. This is insane yet intriguing and informative. Reminds me of the erowids?sp? forums.
How many times do you plan on inhaling dbol, have you had any extremely scary side effects besides not thinking and hearing the humming of the universe. Are you getting more muscle mass? Do u train? Also there should be a disclaimer for the naive and young to not try this lol. Also if it does not go into the bloodstream right away would it make sense that athletes could use it without pissing it out or testing positive for it. Would it be found much later after the fact of inhaling it. I wouldn’t try this because of the legality and what not just curious.

73

“What is the mind.”

74

Interesting reading, would be interesting to see some real 3rd party data here. Like your blood work, etc.

75

tbh I fail to see how its any more “insane” than taking these hormones orally, intramuscular, subq, transdermal or any other method of administration.

Lets not forget there are a lot people out there who think you guys are insane and weirdos for wanting to put synthetic testosterone into your bodies. How is giving him that attitude any different?

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Aussie,

I believe there is a clear line between using substances to give one a “high” (which a lot of forum members think is going on in this thread), and using HRT to relieve ourselves of real (albeit non-specific) symptoms such as ED, brain fog, weight gain, sleep problems, and such.

Sure, HRT can be abused, and unfortunately that’s all too common, giving testosterone a bad name. There’s nothing fair about it.

And sure, a lot of the aforementioned symptoms can be attributed to aging, but I’d venture to say that most folks who show up here are not in their 60s or 80s… we’re talking about 30 year olds with testosterone levels of a 75 year old man - and it shows via these symptoms. Whether it is low T itself or another cause (like hypothyroidism), we have a medical problem and we are here to solve it.

Saying that this thread here, about using dbol up the nose, is about solving a medical problem is quite debatable, despite what the OP says. I do not doubt the OP’s intelligence and motivation, but Batman00 said it best when he said “I see the intellect. I see the scientist. I see the logic. But I also see the addict.”

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But he already made it clear he had mistakenly not mentioned he was using nootropics as well, not that the dbol was causing such effects.

I can only think people are labelling him addict because of the association of nasal administration with addictive drugs. That being the case, just remember some people think TRT users are “druggies” for using needles, yeah? If it were plain oral administration of dianabol, I cant think that the response would be the same.

Correct me if I’m wrong but the idea of using synthetic androgens as being possibly advantageous over testosterone in HRT isn’t exactly a new idea? One that just hasn’t been explored to any great depth because of the massive amounts of red tape and politics most doctors find themselves in?

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[quote]Aussie Davo wrote:
But he already made it clear he had mistakenly not mentioned he was using nootropics as well, not that the dbol was causing such effects.

I can only think people are labelling him addict because of the association of nasal administration with addictive drugs. That being the case, just remember some people think TRT users are “druggies” for using needles, yeah? If it were plain oral administration of dianabol, I cant think that the response would be the same.

Correct me if I’m wrong but the idea of using synthetic androgens as being possibly advantageous over testosterone in HRT isn’t exactly a new idea? One that just hasn’t been explored to any great depth because of the massive amounts of red tape and politics most doctors find themselves in?[/quote]

Davo, Have you read this thread? If you had any experience/contact with illicit drug users you would see the shocking similarities. To say that people are labeling him an am addict because he snorts the Dbol is ridiculous. Read the thread man.

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[quote]Hook24 wrote:

[quote]Aussie Davo wrote:
But he already made it clear he had mistakenly not mentioned he was using nootropics as well, not that the dbol was causing such effects.

I can only think people are labelling him addict because of the association of nasal administration with addictive drugs. That being the case, just remember some people think TRT users are “druggies” for using needles, yeah? If it were plain oral administration of dianabol, I cant think that the response would be the same.

Correct me if I’m wrong but the idea of using synthetic androgens as being possibly advantageous over testosterone in HRT isn’t exactly a new idea? One that just hasn’t been explored to any great depth because of the massive amounts of red tape and politics most doctors find themselves in?[/quote]

Davo, Have you read this thread? If you had any experience/contact with illicit drug users you would see the shocking similarities. To say that people are labeling him an am addict because he snorts the Dbol is ridiculous. Read the thread man.[/quote]

I read the thread mate, the same attitude is given by people when they read steroid users reports.

Most steroid users literally fit all the DSM criteria for addictive substance abuse behavior, but I don’t treat them as “addicts” or “druggies”.

Honestly from where I’m standing he just seems overly enthusiastic with his writing, I’ve seen this before and its probably the case he is exaggerating what would otherwise be a not so significant event to you or me.

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[quote]Tattoo85 wrote:

[quote]Isochroma wrote:
5F-AKB48[/quote]

And this confirms a couple comments about this sounding similar to illicit drug trip reports. Let me guess OP, you keep pretty up to date on the research chemical/designer drug world? I don’t have any problem with that personally, but what you’re doing is already pretty far out there, and it would only loosely be considered TRT to the vast majority of people. You talking about recreational drugs, using terms almost exclusively used by those in the recreational drug scene, and writing this in such a way that someone would describe their acid trip does nothing but discounts any valid information that you might actually have.[/quote]

This is an attitude that seems to be appearing quite a bit in this thread. I suppose by the same token, we should discount the validity of the structure of DNA and PCR technology, quite possibly the two greatest discoveries in molecular biology, because the people behind them were on psychedelic drugs at the time.

I’m not saying that the OP is necessarily on to something (only time, careful study, and replication can say that), but his relationship with the rec drug scene is largely irrelevant.

The main critique I have with the way this is conducted is the lack of scientific method in his approach. Though he uses science to support his position, drawing any conclusion of any sort would be extremely dangerous, as this is no more than an anecdotal report (albeit a well-documented one). There are no controls (and thus no way to account for variations due to placebo effect, individual genetic variation, etc.), a sample size of one, no blinds, and the experimenter is not impartial. Additionally, as the subject/experimenter is using a cocktail of nootropics, it is difficult to identify the cause of any of the reported cognitive effects.