Hey Pilchard,
I read this whole thread last night while I was laying on the sofa. I’m like you, in the UK and struggle with high E2 when on TRT. I found a new doctor through Balance My Hormones who I’m working with, and although I’m not in the sweet spot yet, I feel like they actually know what they’re doing and are making sure we make adjustments at the right time and monitor accordingly.
Also, like you, I’m prone to reading and making lots and lots of changes to try and fix things (I’m also struggling with insomnia at the moment, which is how I found your post), but the trick is small changes in a controlled fashion, with bloods - otherwise you’ll never work it out.
So - the reason for this post is that I “think” you were almost there, and then changed a load of things and went down a different track. Between the blood test in this post and the one before, you noted that you experienced a period of feeling good, but then crashed your E2 - which you did.
Fundamentally, your bloods looked good, you were just taking too much aramosin/arimidex. If you could get your Oestradiol levels up to around 100/110 I think you’d be “dialed in”.
Oestradiol too high (for you): Insomnia Since Starting TRT - #702 by pilchard
Libido disappeared: Insomnia Since Starting TRT - #729 by pilchard (you’d dropped too low on Oestradiol here)
You were sleeping: Insomnia Since Starting TRT - #731 by pilchard
Too Low: July 19 - Insomnia Since Starting TRT - #732 by pilchard
Based on this, I think your Oestradiol “sweet spot” is somewhere between 69 and 146 pmol/dl (similar to mine). I find my libido is the best weather vane for where I am on test/estrogen - basically it works like this:
Oestradiol too low: I don’t care about sex and nor does my penis
Oestradiol in the right place: I care about sex and so does my penis
Oestradiol too high: I care about sex but my penis does not