Increased Heart Attack Risk?

Pharma TRT
1

There have been several articles lately in reference to T replacement therapy and heart attacks. The summary is that for men over 65 the risk doubled, and for those younger with pre-existing heart problems, the risk tripled. One theory is that by increasing T, you increase the clotting within the arteries. Personally,I have been on it for 2 years now without issue and have no pre-existing conditions or pre-cursors for heart trouble.

Does anyone in the forum have any ideas/theories as to what might be the cause? I know my previous doctor would not prescribe an AI while on T, and as expected, my benefits were negligible. Is the lack of an AI at the root of these problems now being reported?

This is just a question for discussion/knowledge sharing

thanks

2

From the articles I read, most of the problems were with older men like you said, and they likely had pre-existing issues that the T made worse.

3

@catfish74…agreed, older men with pre-existing conditions that “T” made worse, but how?

4

That I don’t know lol. The info I read didn’t really go into details, and I would just be guessing if I threw anything out there.

5

That study was really a poor exercise but it got media attention.

6

I wouldn’t doubt that it is an indirect result of sky high E2 levels causing the clots. Did they not control for that?

7

[quote]postitnote604 wrote:
I wouldn’t doubt that it is an indirect result of sky high E2 levels causing the clots. Did they not control for that?[/quote]

By what mechanism?

There are lots of links with high hemoglobin and heart attack/stroke risk. It makes sense, thicker blood is more difficult to pump than thinner blood. I think it is very important to monitor it closely. Mine was high for years and TRT increased it well above range. I finally saw a hematologist who prescribed phlebotomies and after only 3 it is at a manageable level in the 15 ng/dL range (he wants it below 16) after being as high as 19 at one point. This is about 3 weeks since my last letting, so it seems to be stabilizing somewhat.