Abstract of an interesting study comparing impact of AI on several factors, including T and Estradiol, at 1mg/day and 1 mg 2x/week.
Another abstract, the only useful information is :"… in response to inhibition of the aromatase enzyme, which converts androgens to estrogen. Fifteen eugonadal men over 65 yr were treated for 9 weeks with 2.0 mg/day of anastrozole, an aromatase inhibitor. After 9 weeks of treatment, there were significant decreases in estradiol, estrone, and sex hormone-binding globulin levels by 29%, 73%, and 16%, respectively, and total testosterone increased significantly by 56%. "
That study did not report the hormone levels after anastrozole. The E levels may have been way too low. And a study like this does not address long term therapy or costs. It is just a big hammer.
Study 1: Starting E at 26 was low, but not in comparison to starting T, so the ratio was poor. Results on E for 1mg/day were the same for 1mg twice a week. That is the self limiting effect that often refer too. Note that 1mg/day at pharmacy prices in the USA would cost $2900 to $3600 per year.
Study II: Was 14mg/wk, or $6000/yr. This was not a study to determine anything therapeutic, but wanted to see if the hypothesis that low[er] E in men would disclose evidence of bone loss processes. The reduction in E was quite small considering the dose. The self limiting effects again. They should have used femara if they wanted to drive E to very low levels.
[quote]MichaelOH wrote:
Abstract of an interesting study comparing impact of AI on several factors, including T and Estradiol, at 1mg/day and 1 mg 2x/week.
Another abstract, the only useful information is :"… in response to inhibition of the aromatase enzyme, which converts androgens to estrogen. Fifteen eugonadal men over 65 yr were treated for 9 weeks with 2.0 mg/day of anastrozole, an aromatase inhibitor. After 9 weeks of treatment, there were significant decreases in estradiol, estrone, and sex hormone-binding globulin levels by 29%, 73%, and 16%, respectively, and total testosterone increased significantly by 56%. "
The reduction in E was not impressive in any of those studies. I was surprised. And yet, there are anecdotal reports, such as the 2 case studies, which suggest that whatever reduction one gets out of Arimidex can be very satisfying.
[quote]V R wrote:
MichaelOH wrote:
Screw it. You got Crislers protocol. Do it yourself. You don’t need a scrip for Test, HCG, or anastrozole/arimidex. Get your bloodwork through LEF.
Great idea. So when he has to travel and takes his stuff with him, like most ADULTS, he is transporting illegal drugs across state lines. Schedule 3 drugs at that.
Have fun in jail.
Possessing illegal drugs doesn’t seem like much of a big deal until your a grown adult with alot to lose. I know because Ive been there. [/quote]
Arimidex/anastrozole is not a scheduled drug.
You can find it online sold as a research chemical with a basic google, and many places even take credit cards.