When ever I use HOT-ROX I continue to use Creatine, I see no reason to stop. Just keep in mind that you may be losing fat but due to the water retention sometimes caused by Creatine your scale weight may not change. A lot of good benefits from Creatine IMO to keep on using it even in that situation.
Caffeine can affect the absorption of creatine. I would wait 2 hrs after taking HOT-ROX to take creatine or take the creatine then the HOT-ROX 30min later.