Hormone Fluctuations, What Gives?

Ok. When I switched to 50mg every 3 days it was pretty disasterous on libido, gym, and made me crazy as my E dropped to the teens.

Maybe I will try the hcg 500iu EOD to see how that works and if no response switch T dosing to 50 EOD as well. Again not to worried about estrogen at this point if I can get E higher at least I’ll know I’m makihg some progress.

You need to move to two larger T injections and do HCG EOD, if switching to three injection a week crushed your E2 levels than it suggests you need larger peaks on T-cypionate.

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Yeah well I’m doing 2 100mg injections now with a T level 1200’s consistently over the last 2 years. Unsure how much larger of a dose I should be doing?

I switched to 3 a week but had dropped the total dose to 150mg for fear of excess estrogen. The results of this experiment were disasterous after 3 weeks.

The hcg EOD is easy. I’ll start there for sure.

Careful man. A lot of guys on these forums think all doctors are stupid. I’m an endo and apparently I know nothing lol. 38 two kids and one on the way, 6’1 almost 235 currently and two bodybuilding shows won. Spectacular labs.and over 8000 current patients and 25000 in our practice group and a professor at a research university with one of the best oncology centers in the world ( the James) never have we ever established a baseline for when our patients feel best. It’s all based purely on each patient. I have some guys with zero libido at 25 e2 and some with raging libido at e2 85. There are far too many factors at work. It’s neurotransmitters Involved as well. But yea. Bro science all the way. Me and @Shadow_Pro etc on Pharm are all idiots. Haha. Just like when I posted about estrogen being the dominant libido hormone based on a seminar on TRT in London and it’s abour ratio of estrogen to testosterone everyone was like blah blah sweet spot etc. everyone is so different making blanket statements is so reckless.

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Yes I know my docs pedigree and have open access to him at any time and consult him before any changes.

I do know this peak and valley of my estrogen and how it effects my libido is a major issue for me that we cant seem to get right.

What do you think about ratios? I’d love to hear your take in general or in my situation.

@CrushCity1 he willing to have you try testosterone prop ? There are some very bright guys on these forums and also an equal amount of ridiculous commentary by people who have basic anecdotal ideas at best. You’re smart to run everything by your doc.

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I think he wouldnt be against it. He’s very progressive.

Does this aromatize better? I’m willing to try anything for consistency in libido.

Yeah I email him, he copies the fellow. The fellow is actually very interested in my case since I’m “challenging”.

So prop doesn’t really aromatase better per se - what you want is a very fast acting test you can administer very frequently. Even though you aromatize slightly the peaking of prop happening quickly every day will give you the outcomes you want. I mean you could try suspension but medically I wouldn’t advise it. Do you use a methylated b vitamin complex or SAMe?

No I do not use these supps. Only whey protein and betancourt bcaa plus. And cialis daily.

Also how do you feel about the larger hcg doses recommended? 1000 3 times a week. The fellow was ready to go cyp 50 EOD but attending over ruled and said to try the extra hcg first.

I understand his logic behind the hcg dose and it will help in the short term. I much prefer the frequent dosing of test. Sometimes I have guys use 20 mg cyp daily to great effect especially in those who have low e symptoms. Your libido issues are much more interwoven with neurotransmitters. Has he suggested a neurotransmitter test? Remember estrogen feeds serotonin.

No he hasn’t suggested that? What NTs specially? Serotonin, norepinephrine, dopamine?

Are you an overly anxious person? Nervous? Do you sleep well?

Sleep very well.

I’ve actually never had anxiety until I continually started crashing my E2. Now occasionally I do get anxiety more around the lower E feeling.

Severe anxiety with E in single digits. Not a good feeling.

I feel im so close. Last year was terrible on anastrazole. Now that I’m off I’m a better person. If I can figure out libido I’ll be so happy. It’s killer on the marriage.

I feel that having my E2 literally in the teens for a year has somehow completely jacked my libido. I went in for trt due to fatigue, low libido, lack of motivation and energy.

Trt gave me a passion for life again and professionally I’m killing it. The libido has really been a roller coaster though. When I’m on libido wise and I see what I could feel like Daily it’s the best ever but it’s way to short lived for me.

You know you need healthy estrogen levels for libido, it’s not just about testosterone, but a combination. No one has libido when estrogen is low or erections for that matter. Your body is just more temperamental is getting the estrogen levels right for you. Then again it could be your liver clearance of estrogen is just too good.

Perhaps you somehow permanently disabled the enzyme that converts testosterone into estrogen being on the AI for a year. Dr. Crisler mentioned once a guy went on an AI and never recovered his estrogen levels, it was similar to the way Finasteride disables the enzyme that’s responsible for DHT conversion.

Man don’t scare me like that. Gonna try to keep it positive.

So if my goal is to drive more E what’s better. Remember I’m on cyp 100mg twice a week.

Go 50 EOD or go say 120mg 2 times per week ( this seems excessive) ?

The test prop is a new option that I need to read up on.

Larger testosterone peaks, larger estrogen peaks. T-cypionate 2 times per week, HCG EOD.