So many doctors would say not to TrT if they see your total test 600…also a lot of members here believe it is a good value because it is “normal” 
As far as I am aware the last 2 you mentioned are the main two and the others are intermediaries using those doctors as prescibing doctors sub contract (not sure on the proper term for this)- yes there are probably some on Harley Street but they are well out-of my price range.
I’ve used BMH in the past, they were fine (had me on sust) with a Dr who runs his own clinic and is a touch cheaper than BMH, he’s fine with me on Test E no HCG or AI.
I think it runs to around £1350 pa for everything all in.
Is that the Doncaster based one mentioned above?
Or is there another I’m not aware of- you’re probably not allowed to name them (I havent checked forum rules)- but I’d like to know whY to Google to find them so I have more options.
Thanks!
God the fatigue today has been unreal!
I need to get back in a clinic asap- cant carry on like this. Just completely flattened.
For me fatigue has been by far the worst symptom- I’ve got lots of the others but the fatigue is the most unlivable
@alex_uk I’m presuming you get the Test E ampoules in the 250mg/ml 1ml glass snap top things that seem to be what it comes in over here.
Are you breaking those and putting them unto a steripe multi draw vial to make dosing easier?
I cant find anywhere to buy those other than the clinic down south…
Yea it’s the amps, always has been on any of the tests I’ve used (sust, prop, E) - I just draw up however much is needed per injection and store it in the syringe.
I have the same problem with SHBG and I’ve been on trt since last year after many years of depression, anxiety, social isolation, ed, fatigue and brain fog that almost ruined my career. I still don’t understand one thing. How can you than explain other people with high SHBG who are asympthomatic? examples:
I did not watch the videos, but it probably depends on their total T production. I suspect that I’ve had high SHBG all my life, but it did not become problematic until I reached my mid-50’s. I suspect that it was a combination of Total T production going down with age and SHBG production going up with age. This causes a faster drop in Free T than guys with “normal” levels of SHBG.
I read somewhere, though I’ve since lost the reference, that the reason some of us have high SHBG is that we are genetically programmed to add extra sugar molecules to the SHBG protein and this effectively doubles the half life of the protein. So for every molecule of SHBG we produce, it has double the effect in lowering Free T. When we are young and produce more Total T, the effect is not noticeable. However, as we age and Total T goes down and SHBG goes up, we begin to feel the effect. For me, this started around age 40 and got progressively worse through age 55 when i finally started TRT.
Whats your protocol if you don’t mind me asking?
Is there certain protocols that tend to work better for high shbg guys as opposed to low total t more ‘standard’ low t patients?
Very easy. There are people who feel good and have no symptoms with ratively low testosterone.
Or others like me who had all the symptoms with midrange values.
Everyone has different needs. As simple as that
My current standard protocol is 125mg per week in an every 3 days (E3D) protocol, although I am currently experimenting (again) with 140mg per week in a E2D protocol. I don’t feel any difference between 125mg and 140mg, so I my plan is to run labs in a couple weeks and make a decision to change or not. I arrived at 125mg per week by conducting a dose-response experiment with various doses of T and measuring Free T. See the graph below.
I have also experimented with adding low doses of stanozolol(windstrol) at 5mg/day and also with oxandrolone (Anavar) at 10mg/day. Both were very effective at reducing SHBG to be within the normal range. However, I see no advantage to using these synthetic steroids (that I need to purchase through UGLs) because they are suppressive of the HPTA and you need to continue TRT. They simply allow you to use a lower dose of T. I’d much rather simply use my scripted T to saturate the protein with the same outcome.
And what does that do to Estrogen at e3d? Any ai needed?
What is your calculated free test in ng/dl?
I do not use an AI. I’ve observed that E2 is a highly variable hormone and any attempts to control it generally result in crashing it to very low levels that make matters worse.
Case in point. In the dose-response experiment shown in the graph above, my highest E2 using the (LC/MS method) was (as one would expect) at the highest T dose of 245mg/week (in an E2D protocol). My E2 was 70.4 pg/mL with a normal range of 8-35. HOWEVER, at the next highest dose of 204mg/week (E2D protocol) and have 2 labs spread 6 weeks apart and they both returned E2 levels near the bottom of the normal range (13.6 and 12.1 pg/mL), both with no E2 control. Then there’s the 109mg/week dose with no E2 control which returned an E2 level of 63.5 pg/mL. When I attempted to plot the E2 level in the dose-response experiment, I got a very poor correlation and the slop of the line was actually negative, predicting higher E2 at lower T levels, which made no sense. My conclusion was that measuring and treating E2 was a worthless endeavor.
The units are pg/mL (see the Y axis title).
Yes but I was interested in your free t in ng/dl if you calculate it from your total t, shbg and albumin from the formula in google
Once or twice per week and high enough dose. With that shbg you may need to get your total t above 1500-1600
The graph is Free T. In this experiment, which was conducted over the course of about a year (a little longer), all measurements were conducted using the Direct (immuno assay) method. I plan to switch to the LC/MS method in future labs (next labs in a couple weeks).
At most doses >110mg/week, the Total T was >1500 ng/dL, which is the upper limit of the direct method that was used for the tests. As previously discussed, I plan to switch to the LC/MS method for future labs for various reasons, one of which is that it does not have an upper limit.