I have been lifting for 45 years, on TRT ( sometimes TRT+) for a decade, and began Serostim 4 weeks ago at 1-1.5 iu’s daily. The sides have been joint pain (often an exacerbation of preexisting shoulder and knee discomfort) and fatigue with a capital F! On the plus side I see growth (esp deltoids) and healthier appearing skin colorization (esp facial). I really don’t want to give up. I know we’re all unique but generically speaking: can I anticipate a reduction in sides over time,i.e, soon!! Gratefully suffering
It’s probably mineral retention especially sodium.
Increase water and potassium intake to at least equal sodium (unless there is a contraindication against).
One, you could start titrating up. Even replacement doses give some water retention where it’s best to gradually increase. Two, yes it does usually improve some to all but can take time.