Growth Hormone and Hyperplasia

hyperplasia, generally a form of muscle growth that many of us know nothing about (splitting of muscle cells to make more) has been said to be related with growth hormones, natural and steriod use. Any one here know a little bit more about this subject because if it were true, i would be using HIIT workouts every night before bed just to up my gh productions

I was under the impression that most of the anabolic effects from GH and the other peptides come from satellite cells and NOT hyperplasia, just like Bushy said.

they are one and the same. you get satellite cells becoming attached, creating a new cell, and thus causing hyperplasia.

It is believed this happens naturally at a very slow rate from weight training and the bodys natural GH levels…for that reason it is believed to occur at a greater rate from exogenous GH use (or IGF-1 use) but can also occur endogenously from use of steroids like test or tren which have a positive effect on endogenous muscle cell IGF-1 levels.

FG

haha…you can count me out of that experiment bushy.

thanks for the post. my understanding of hyperplasia is pretty basic so i appreciate the help to clarify.

I can’t give any evidence because i don’t have any and haven’t read any. just a lot of theory. all i know is that it is thought to occur (i assume based on animal studies). whether it is happening through the donation of nucleii to existing fibers or the creation of new fibers…I can only speculate that over time the fibers would (after receiving a number of new nucleii) seprate and become 2 distinct fibers.

I would think either way you are accomplishing the same goal (ability to create/support more contractile muscle tissue). The real point of it is, I believe, that you can increase a persons total muscle mass over and above what they are currently capable of and permenantly change their minimum/baseline muscle mass when not training or simply doing maintenance training.

wow, nice comments guys. looks like you guys know your stuff, although it would be cool if scientest could run some more studies on this factor so we could find out more i know it will me a long time before we uncover this bit of information

personaltrainertoday.com/articles/publish/article_431.htm
very interesting article that gives a seperate point of view, just skip over the weight training cat part, that study is useless, cats dont prove anything in humans

I know this was an old thread, but I was researching hyperplasia and I came across this. One thing that I have heard is that extreme loading on the negative or eccentric side of a repetition may be able to stimulate hyperplasia.

Of course like it’s already been said nobody can know for sure if hyperplasia occurs naturally because who wants to give up their pec or bicep for fiber counting lol. Anyways, it would kind of make sense because in order to induce hyperplasia there would have to be an extremely high amount of stress placed on the muscle and negatives would make sense as they tear apart the muscle fiber. I use negatives quite a bit with my workouts and with adequate rest, my strength is always increasing. If I hit a plateu on bench, I’ll do a whole workout of negatives and rest it for a few days and sure enough a few days later I’ll come back and my max will go up.

I’m not saying I’ve found the magic formula to hyperplasia lol, but negatives would sure be something for research people to look into because they produce so much of a tear and stress on the muscle. It would be cool if they could get an device sensitive enough to scan your muscle and see individual fibers but that’s like star-trek shit I’m sure ha…

It would be awesome to study this… I’m a health and exercise major at the University of Oklahoma and we have to do a senior research project to graduate called a capstone in order to graduate. I might have to save this for graduate work though because I think this is a little too deep to get into for undergrads… For now just keep hittin those negatives!

My chest workouts usually go to where I do a max test every friday on chest day. Every 2 weeks I’ll do for my flat bench portion of my workout all my sets just negatives… More often than not the next max day I’m up 5 pounds more than the last… It’s pretty awesome. Before this last fall semester I only did dumbbell bench and I was super weak on flat bench. Like bodyweight would be my max which was around 170.

With DBs I’d rep 90s but go to regular bench and only do like bodyweight tops. The first max I did at the beginning of the semester I got 185. The last max I did at the end of the semester was 230! I was so amazed. My size went up insanely too… Basically just super high volume and negatives every so often kept me steadily gaining. If anyone has trouble in their bench go negative and rip that shit apart lol. Don’t know if hyperplasia happened but definitely got some good hypertrophy lol. Anyways this has been a ramble…