Got My Results, Need to Cut Back on AI

It’s been a while since I’ve posted on here but long story short: was experiencing symptoms of low T, so I got a blood test (LEF) in 2008

T, Serum: 341
T, Free: 8.8
Estradiol: 44

I wanted to try the AI route first so I’ve been running 0.1mg Anastrozole (research liquid) ED for about a year now. Just got the test results back

T, Serum: 622
T, Free: 15.2
Estradiol: <7

I poked around getting the second test because I was so happy with the results, but obviously I’m concerned with the very low E2 number. Any ideas where to fall back to on the AI? I’m thinking either 0.05 ED or 0.15 EOD but those are complete guesses. If anyone has experience dialing in I’d appreciate the help.

Which test specifically did they use for your E2 test? If it was the “Extra Sensitive” test offered by Lab Corp there has been a lot of false low readings. You say it has been a year; how do you feel? How is your libido, quality of erection, strength of orgasms, and how do your joints feel?
I, along with many others, realize not everybody gets sore joints from “too low” of E2 levels.
Excessively low E2 reacts very different in me and a few other men I’ve spoken with; we have great erections, but are unable to orgasm and we never get joint pain.

You are effectively using 1/4mg of adex a week and have gotten great results from it. If it was me, I would leave well enough alone. Your numbers look very good, it’s been a year, they’re not like to change, and if you feel better don’t change anything.

Just my .02.

KNB: He takes 0.1mg every day. That is .7mg/wk. Given that his TT is 622, that level of TT suggests that 0.7mg adex would be reasonable. I am glad that you remembered that there have been some bogus E2 labs from Labcorp. Labcorp does the E2 in regional labs. So the problems may be geographically isolated.

The TT and FT increases are impressive. The FT could be a lot higher. This suggests that SHBG is reducing FT. If E2 was <7, we would expect lower SHBG and higher FT. So the FT level does support the suggestion that the lab number could be bogus.

This is a great AI only story.

Thanks for the replies. I didn’t realize there were some false reading on the E2 test. Guess I need to spend more time here to keep up with things.

Incidentally, I didn’t specify the extra sensitive test because I’m feeling good. No issues with joint pain and wood is good. I had seen the issue with not being able to orgasm but that’s not a problem. I suppose libido though could be a little better, but that seems to be the only downside. Everything else is night and day from where I was a year ago.

[quote]KSman wrote:
KNB: He takes 0.1mg every day. That is .7mg/wk. Given that his TT is 622, that level of TT suggests that 0.7mg adex would be reasonable. I am glad that you remembered that there have been some bogus E2 labs from Labcorp. Labcorp does the E2 in regional labs. So the problems may be geographically isolated.

The TT and FT increases are impressive. The FT could be a lot higher. This suggests that SHBG is reducing FT. If E2 was <7, we would expect lower SHBG and higher FT. So the FT level does support the suggestion that the lab number could be bogus.

This is a great AI only story.[/quote]

Don’t know how I missed the math on that one… Once again KSman, thanks.

I agree this is a great AI story, and I hope more men take time to read it.

TRT isn’t always needed to fix the problem we aging men experience, but if an AI doesn’t “fix” the problem, then TRT is always an option. I have friends that were experiencing lowered urine flow and mediocre erections due to BPH (apparently) caused by elevated E2, and after self medicating with liquid adex their urine flow returned to normal and so did their sex life.

It is so amazing how the world we live in with all the processed food, bad air, chemically impure water, and phytoestrogens in a list of things to numerous to name, how we men can still urinate and have sex over the age of 40. The last time I checked; 65% of all American men over 40 experience some form of Erectile Dysfunction. Hmmmm, I am curious how many of the affected men in this survey could have their QOL returned by lowering their estrogen levels using an AI?