First Time on an AI on TRT. Your Opinions?

I’m been on TRT for 3 years. The first year I was on 140mg test once a week, no AI. On that protocol:
E2: 22
FT: 11
TT: 900
SHBG: 48
Sex drive and erections not bad. Then my Doc suggested 100mg test E3d shots, no AI.
E2: 49
FT: 30
TT: 1350
SHBG: 35
The results were taking after three months of the protocol, the first month it was pretty good with libido and erections but after three months was worst than with my old protocol. Then he suggested to take Anastrazole 0.25 twice a week. I did it for a week and my erections got better. But I start listening Jay Campbell, Dr Nichols…saying that Anastrozole was deadly, so I got scared and I quitted taking it. I start doing 50mg EOD and Proviron 50mg ED. I did it for two months, my erections got better. I run out of Proviron, so I did 25mg ED instead of 50ED. For two weeks my protocol was EOD 50mg test and 25 mg ED Proviron, my erections got worst than ever and that is when I got my bloodwork:
FT: 20
E2: 59
SHBG: 50
TT: didn’t care at this point
Now my protocol is E3d 100mg test and 0.25 Anastrazole twice a week, no HCG. I can tell E2 has a huge impact on my libido and erections, so I decided to take Anastrazole. Has anyone been taken Anastrazole for years and feel good?.

You’re not going to find many guys on anastrozole having success in the long term because guys lose weight and ditch the anastrozole. Also a lot of guys find it difficult to dial-in anastrozole and are always having to make adjustments.

Docs are saying blocking estrogen has other downstream and upstream effects which isn’t hard to imagine. Whenever you change something about how the body functions there always seems to be other systems being affected.

I noticed you seem to do better when your FT was closer to 11 ( less aromatization), then you changed your protocol and FT ->30, then 20. I think you needed a dosage reduction without the AI which should be the goal. You should try to get FT-> 15 at trough which would have FT at peak somewhere in the high teens.

You could also try some DIM and calcium glucarate which Dr. crisler had stated increased libido significantly is some of his patients. Like everything else I over-responded to calcium glucarate and erections went soft.

Dandelion root also can help with estrogen metabolism.

2 Likes

Let’s recap…

140mg things were ok so doc decided to up it to 233mg because…?

How long were you on the new higher dose before you started the AI? Libido took about 4 months for me when I upped my dose and stuck to it without changing shit.

1 Like

I’m on my new protocol for one week. I read medical articles regarding the Anastrazole effects on the endocrine system, these articles say that Anastrozole increase LH by blocking the conversion into E2 and also increase FT. I only take 0.25mg E3d. By the way, doing EOD injections increased my E2, SHBG and decreased my FT, more frequent injections don’t work for me

Nobody out there taking Anastrazole?

I’ve taking it for the 8 years that I’ve been on trt. I used to take it like clockwork .25 twice per week with my injections but I over responded to it and my e2 would crash badly. For the last two years I only take when I feel some symptoms like itchy nipples or just feeling bitchy and then I take that one low dose and don’t take it again for weeks. I’ve been considering looking for alternatives like DIM. Btw, I blast masteron about two times per year and I never need an AI during that time.

Great, now I’m scared of Anastrazole again lol. The only problem I have with high E2 is erections. If I take lower dose of test my E2 will be lower, but my FT will be lower also.

Try with zinc aspartate at least 2x30mg daily. Get some high quality brand like Solgar.
Im pretty sure it has lowered my estrogen since I started TRT. I may stop it if estrogen does not increase to healthy levels. But I also need zinc…

Also I don’t understand why on EOD protocol my E2 went up, the less frequency the less my E2 is.

There are a lot that are not on the forum. Forums seem to be run by a minority of dominant personalities. This one was very active pro anastrozole guy here a couple of years ago, the major proponent, but he left when questioned by some others.

There are TRT/men’s clinics who seem to put everyone on testosterone, hCG and anastrozole. I know guys who will think the doctor is committing malpractice by not prescribing it.

I know some guys who have always used it and are happy with the results they have achieved. I know just as many, maybe more, who do not use it and some who have never even heard of aromatase inhibitors. All report doing fine and most, by far, with once weekly 200mg injections.

Personally, I used 1mg twice a week for about four-five years, keeping E2 in the mid 20s, with 200mg once weekly testosterone. About two and a half years ago, after studying Neal Rouzier, and a few others, I decided to experiment and stop. Also, because in part, due to that I never experienced much in the way of high E2 sides from my competition/AAS/PED days on much higher doses. Pretty much just some morning sickness nausea towards the end of particularly long cycles, but only a few times. I did train with and know some who had trouble related to “roid rage” which we know is usually estrogen.

without anastrozole, I noticed my joints felt better. I never gave joint pain much thought because it is always there (still) and due to my age and history, I accepted it. However, they feel noticeably better with higher E2. I’m not jumping under 200kg cleans again, regardless, but it’s better.

Lipids improved significantly with the higher E2, which is what Neal said would happen, probably by about 15%. I have no high estrogen sides and it runs around 45-50 with the one test and as high as 70 with the other.

Looking back, or if I am starting TRT new now, I would avoid it unless there was no other option. Some guys simply do not want to take lower doses or take multiple injections, or use scrotal creams. Some are terrified of higher E2, water retention, or whatever it is in their mind.
Maybe if I was a past AAS guy with a history of gyno (not mastalgia) or just one who had difficulty with E2 in the past. Or if I am really obese. I don’t know, still think I would go without it if at all possible.

Overall, I lean heavily away from using it, but I’m not ready to say it should never be used.

3 Likes

Your protocol is just once a week shot of 200mg test?. No HCG, no AI?

How low was your E2 when you crashed it, also how much test did you inject a week?

It went down to about 9 and I felt awful. My bones ached and my dick didn’t work. I was taking 200mg per week.

What is your protocol now and how do you feel?

It’s still 200 per week split into two injections and my Dr prescribes me .50 arimidex twice per week but he knows that I rarely take it. That’s just way too much AI for me.

How do you feel?Do you take HCG?

Yes, once a week, 200mg. No hCG or AI.

I started TRT 4 weeks ago. First week or so I decided not to follow doctors orders and not take HCG or an AI. But, I noticed that my balls were shrinking and my ejaculate became coarse, thick with less fluidity. As much as I didnt care for not having full balls, I realized that theyre a big part of sex for me. My wife likes to suck them and she was not happy with the consistency of my ejaculate. So Im one of those guys whose partner prefers full balls, and enjoys getting a mouth full of runny jizz. She didnt realize it either until it was gone. So I started following doctors orders and Ive decided to cut down the HCG from 800iu a week with 1mg of AI, to 400iu a week with .5mg of AI. So far, my balls are full again and my ejaculate is back to normal. Will run labs in 2 weeks and then will see what happens. As for me, having full testicles is part of foreplay.

2 Likes

Sounds like a keeper

3 Likes

I definitely concur with that statement

1 Like