Favorite TRT Provider? In Detail, Why?

@Andrewgen_Receptors If you are going to try it then either inject Test suspension (very small impulse) or use Nateso/Empower nasal gel. Least risk.

The former would VERY hard to get from legit pharmacy. The latter very simple. Natesto expensive, Empower nasal gel much more reasonable. Would love to see your blood work 1-2 hours post application and LH before and after 8 week trial.

Reasonable chance you can keep your endogenous T going.

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I for sure still have this going for me. One day pretty happy, the next depressed.

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another stupid graph.

1x or at most 2x nasal gel daily. 3x would give you some HPTA suppression most likely. I’d start with 1x (but that’s just me).

Also testosterone troche is another compounded option (buccal and don’t swallow). Stick way up in your gumline.

@Andrewgen_Receptors

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I think it is a beautiful graph.

They need to get some with some nicotine in them too. Then we wouldn’t have to worry about guys having too low of T with them.

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image

Had this before TRT and have it after. The only thing TRT has helped me with is a beard and muscles. And lightening up my wallet of course.

I’d never come off, but it didn’t really do any of the things I wanted it too

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Compare with nasal gel PK…

I’m fairly read up on injection TRT but still very new to the nasal spray.

We understand other hormonal responses (E2, SHBG, Prolactin, etc.) when injecting TRT but what would I expect with either troches or nasal spray? Obviously TT increase but I’m hoping for more consistency - I just don’t want my other hormones to go out of wack in response.

I don’t see a baseline production in your graph. Any indications on improvements over baseline?

Those would behave as close to how they behave with endogenous T pulsing. With a young man like yourself, typical pulsing on LH (see the TRT thread). T is never made constantly. Familiarize yourself with hormonal PK under normal physiology in a well functioning male.

Why? That’s not how human physiology works WRT HPTA regulation of T/E2/etc etc etc.

Agree, but if the HPTA isn’t functioning properly (very low T in a young healthy male, alongside significant behavioral changes, for example), maybe consistency - although less ‘natural’ - could help quite a bit.

Same. Not feeling your best 100% of the time is well… being human?

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I think a lot of my issues is PSSD from taking lexipro. I’d give both legs in a heartbeat to go back in time and never eat them.

No cure. Just my luck!

So then it’s a tradeoff between testing your hypothesis vs losing partial/all HPTA function.

Short pulses seems to be the way the short acting stuff either avoids shutting your down or in some cases actually restores partial function.

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I should also add that I have been with several TRT docs from Endos to clinics and I still choose Defy. They are not perfect but any stretch but seem to have their stuff together. I’ve yet to miss any medication refills etc. I don’t see Saya but one of their other qualified MDs.

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No improvement vs baseline for functional hpta. Some data indicates potential recovery of secondary hypogonadism.

See the natesto thread and this paper:

https://academic.oup.com/jes/article/3/9/1652/5523088?login=true

In your situation since it isnt really clear you have hypogonadism the rub is you could pulse T with little to no penalty.

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Do you have Mike? He looks saucy IMO. Kinda big powerlifter look.

The Generous Provider. Bless Father Mike.

Right up there with our patron saint @lordgains

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No I see Dr. Caulkins. I’ve liked about 80% of what he has to say. Thats an improvement of about 50% over any other doc. I should also add…

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Of course this would only be useful to see if you felt better. It probably wont do much for symptom of ffmi less than 30. I think any treatment for that requires some real skin in the game.

@Andrewgen_Receptors