I’d ask the doctor for the rationale for using it with TRT.
Enclomiphine is a SERM used in men with secondary hypogonadism to increase testosterone.
Briefly, it blocks the hypothalamus from “seeing” estrogen so the body thinks it is low on testosterone since estrogen appears to be low. GnRH is then sent to the pituitary telling it to release, or increase, FSH and LH, which will increase testosterone, which will increase E2, which will not be “seen” so the process continues.
Add exogenous testosterone to the mix and things get more complicated. Enclomiphene essentially alters your brain chemistry. It’s a drug.
I have a guy, an orthopedist, former bodybuilder, who previously used Clomid with good results. He wanted to move to TRT. Started him with testosterone. He wanted enclomiphine as well, talked him out of that and to hCG instead. He liked Clomid, likes test, likes hCG. So now, he’s taking all three. Couldn’t talk him out of it. Currently doing very well, but this will be interesting to follow.
As a side note, with some compounding pharmacies now unable to make hCG, I recently had a pharmacist contact me and tell me they can make enclomiphine, and it’s the same thing…
You got conned. My clinic did the same thing. None of these places want to bother disrupting the money flow between them and the pharmacy they’re partnered with. Instead of stocking HCG—which they don’t carry but rather compound—they’re making patients use an inferior drug. And they’re lying to patients about it. Flat out lying. It’s the reason I bailed on my clinic.
Does enclomiphene vs clomid increase the size of the pituitary? Or does it bypass that too? Compared to when I took Clomid, I had visual problems that could only be due to pressure on the optic nerve. That was not fun?