Thanks. I wonder if there are any such research. As far as I looked, no such finding that exogenous testosteron reduces quality of sperms in terms of genetic
Did they do a D&C? If so they may have been able to identify the problem. It is not you and your testosterone.
Reminds me of one of my patients whose wife miscarried four times. OB told his wife it was because he was on TRT. That was when he contacted me. I told him he was fine, she conceived five times (they already had one healthy child) and asked if they were monitoring her progesterone.
He got back to me and told me the OB said they usually do not do that until after the FIFTH miscarriage, but I they could start her on it next time she became pregnant if she wanted to do so. She took progesterone and had a successful pregnancy for the next one.
Of course I could be wrong, but it seems to me the doctor dropped the ball and then blamed TRT.
Sorry you had to go through this.
By the way, I could not begin to guess how many guys have conceived healthy children while on TRT, most with hCG, but but some without.
I don’t have anything to add except prayer. Very sorry this happened. I had a close friend lose their baby about 6 weeks after birth. Husband is on trt. They tried again a year after the child’s death and have conceived a healthy baby.
I have not read, seen, or otherwise heard of TRT causing reduced sperm quality, though it absolutely reduces sperm count.
There is some bro science out there where bodybuilders tend to father more girls than boys. If I were to take a guess, the environment is not as healthy for sperm; male sperm are faster and stronger than female sperm, but female sperm is more resilient… so in an inhospitable environment, female sperm would survive longer.
But that says nothing about the quality.
I have heard of Metformin having a high correlation to birth defects if conception occurs while taking:
“The drug metformin, widely used to treat diabetes, may cause genital birth defects such as undescended testicles and urethral problems in the male children of men who take the medication, researchers have found.”