Crashed E2 - Uh Oh

No. Rarely on. Your not missing anything. If your concerned about your thyroid I would wait until after you stabilize. Check temps and /or do thyroid labs.

Thinking is more progressive now. We don’t just take massive doses of iodine. Esp if you live in the USA.

My TSH has went from 3.5 to 1.5 in a matter of weeks then back up and so forth. My temps fluctuated as well. Labs move around. If most days you get close to 98.6 u should be fine.

Others can chime in.

1 Like

Red face? Have you taken your blood pressure recently? Sounds like spikes in blood pressure to me. I would look there. Manage stress. Dont over think this thing. Your mind is a powerful force on your body. Relax and let your body normalize. You over dosed on an anti cancer medication that was never meant for the human body. Enough said. Try meditation. Focus on diet, nutrition and exercise.

1 Like

My TITS went Massive from E2…Just kidding but i think you should ask you’re personal T.R.T doctor specialist. what dose of Anastrozole (arimidex) would properly correlate with your TEST dosage he might know the specifics as he specializes in this stuff.

I ain’t any expert on A.I drug dosing but if i was taking 200mg of Test per week, might need 0.5mg every 5 days because a bigger than normal dose. don’t quote me on it, but i would consult with my private Hormone specialist on the matter.

If your Face is really Red too, did you get HCT tested recently? i heard it can cause this, or checking blood pressure regular be a good thing. I have a decent calibrated BP machine at home. @bluffcityrat

BP was 139/95 today. Recently started working out hard for the first time in a while.

Keep up the training every day in some capacity. 139/95 isnt crazy high or anything but it also has to do with your normal blood pressure. I have low blood pressure issues. 90/60ish sometimes. At those levels I start getting dizzy and feeling like I’m gonna pass out. I feel best around 110/65ish. It varies. If you start getting red faced suddenly… take your blood pressure right then. If you continue to train and excersize your blood pressure will sort itself out. Hematocrit as stated above could be a culprit as well if you aren’t already tracking it. Should be below 50% to be normal. Anything above 50% your at higher risk of stroke. Donating blood can help from many anecdotal experiences. I have never had to do this as my hematocrit stays between 41-43%. Dang near bottom of the range.

  • “Normal” blood pressures are lower than 120/80.
  • “Pre-hypertension” includes blood pressure levels between 120 and 139 for the top number, and between 80 and 89 for the bottom number. For example, blood pressure readings of 138/82, 128/89, or 130/86 are all in the “pre-hypertension” range. If your blood pressure is in the pre-hypertension range, it is more likely that you will end up with high blood pressure unless you take action to prevent it.

So much debate this days about blood pressure levels. Never really know where I truly stand. All i know is I’ve lost 30 lbs in the last two years and am slowly getting back to shape. Still overweight technically though. I donate blood every 2 months because right at the 2 months mark I get to the 49-51% range.

Hasn’t this been disproven, relative to TRT? I realize, at some point, you have to draw the line. Tour de France guys run hematocrits into the 60s. There are 40 million people living at altitude with elevated hematocrits and they are not dying.

It is my understanding that TRT does not increase the risk of heart disease, strokes, or blood clots.

Testosterone and Cardiovascular Diseases: Causes or Consequences: The Lesson from the Last 5 Years
Giovanni Corona1 & Giulia Rastrelli2 & Mauro Dicuio3 & Alessandra Sforza1 & Mario Maggi2

Springer Science+Business Media, LLC 2017

Summary Present data do not indicate an increased risk with TTh, but there is also insufficient definitive evidence that TTh is protective. Therefore, further and more specific trials are advisable to better clarify the possible relationship between low T, TTh, and CVD in aging men.

1 Like

Tour de france competitors are also taking huge risk doing this. Riders have dropped dead in the middle of races doing this. It is not a safe practice to ride a liter heavy. Do what yall want. I think it’s all relative to what is normal to each individual personally.

Does your face appear flushed all the time lately? If so I suspect the culprit is high rbc.

Get that checked or simply donate some blood and see if it subsides.

I think you now know. If you drop your TRT dosages you also must drop your arimadex dosage. And if you low enough you no longer even need it. But then most of us like being high enough where a little helps.

And yes it is better to take a little less arimadex than you need than a little more than you need. Yo probably feel fine with E2 levels from 20 to 39. In my case I feel great from 15 to 40. Never been lower than 15 and I am not planning on it, but at 41 I’m emotional with a bit of water weight, so no one is going to tell me that isn’t too high for me

I donate every two months religiously. Just donated yesterday. Still flush.

Love it verne. That was my mistake. I dropped my T dosage and kept the AI dose the same. CRASH!

Now we are going to cruise with no AI for 3 months and see how I feel. Thanks for your input.

Which E2 test did you run, and which lab did you use? This is critical. You need to know this.

Most guys receive the wrong test resulting in artificially high E2 levels. They jump to an AI, crash their E, then their protocol gets thrown completely out of whack.

Not necessarily, here the LC/MS/MS sensitive came back 20% higher than the IA. Go with symptoms and if you have none (I have none), no aromatase inhibitor.

1 Like

You got the right lab. As such, you can take an appropriate action. Had you based your treatment using the wrong lab (we agree it should be symptoms/feel) it would be very difficult to get dialed in. The important thing is that the right lab is run, a baseline is established, and labs are consistent and comparable.

Here are my last labs. You and I are on opposite ends of the E2 spectrum, however, we’d both be in trouble if we used the wrong data to direct our future treatment. I would have crashed my E2, and your’s may have stayed too high. With that said, in my opinion, comparing labs to others is very misleading. Too many variables go into the readings…time of day, which lab, fasting, diet…huge list of uncomparable variables. However, if @bluffcityrat ran the Roche lab we know is E2 was not accurate. We don’t necessarily know if it’s high or low, just that it was the wrong lab and provided misleading information.

image
image.png732x47 6.56 KB

image

I was taking 0.5 mg AI per week and my E2 was in single digits and I felt horrible. Regardless of which test it was I think it’s pretty safe to say E2 was too low. One thing I did find wild is when I dropped my test down to 0.4 ml from 0.5 ml every 3.5 days my testosterone levels went back down to 280-ish which is where I was before I started TRT. 0.5 ml had me up in the 900’s.

I was injecting 50 mgs Monday and 50 mgs Thursday which put my tt at 675. I switched to 60 mgs Monday and 50 mgs Thursday and my tt came back 1040. Slight adjustments make big changes. Also, your body over time can start to metabolize the compounds differently.

I meant comparing testing methods to one another, same lab. I’m just not totally on board with the must have sensitive, LC/MS/MS mindset. In your case, I assume those tests were run on the same sample, I would not let either number drive treatment. Rather, the symptoms, if any, would dictate treatment.