Estrogen does have risks in men for CV health [clots, heat attacks and strokes], prostate, fat, diabetes and mood. But the major problems are mostly restricted to those with low T where the E can drive deep estrogen dominance. For those on TRT, increased estrogen lowers libido and affects mood and energy. Studies will not explore those differentials. There are no large longitudinal studies for men on TRT. Many studies exist where T, E and DHEA have been checked in blood samples of men who have heart attacks.
E dominance causes endothelial dysfunction in men and women. T is CV protective in men just as progesterone is CV protective for women. [Hence the danger in estrogen only HRT for women.]
We will never see TV adds for injected T, there isn’t enough money to support the message. And injectables are all generic, so it is impossible to drive viewers to consume your product.
There is a good thread in this sticky that explores these issues: