i read that cetain drugs and dietery fats lower cholesterol by keeping the liver from expelling the cholesterol into the blood, thus your perceived cholesterol drops. subsequently your liver gets damaged. any one have info to add. laters pk
haven’t heard of this (yet), but as you say, it cannot be any good. shutting down a biological process? nope.
[quote]pkradgreek wrote:
i read that cetain drugs and dietery fats lower cholesterol by keeping the liver from expelling the cholesterol into the blood, thus your perceived cholesterol drops. subsequently your liver gets damaged. any one have info to add. laters pk[/quote]
Do you know what drugs and fats that do this? Where did you get this information?
i will back track the literature i was reading from yesterday. can’t promise that i will find it but i will dig. i know it was from a web site. i do most of my reading know on the web. laters pk
Speaking of livers, how is yours? Didn’t you have elevated liver enzymes a while back?
As far as your question, are you referring to statins:
“The beneficial effects of statins are the result of their capacity to reduce cholesterol biosyntesis, mainly in the liver, where they are selectively distributed, as well as to the modulation of lipid metabolism, derived from their effect of inhibition upon HMG-CoA reductase”
This is a slightly modified version of Ray Peat’s article which can be found at http://www.efn.org/~raypeat/
The cholesterol-lowering fiasco for a long time centered on the ability of unsaturated oils to slightly lower serum cholesterol. For years, the mechanism of that action wasn’t known, which should have suggested caution. Now, it seems that the effect is just one more toxic action, in which the liver defensively retains its cholesterol, rather than releasing it into the blood.
Large scale human studies have provided overwhelming evidence that whenever drugs, including the unsaturated oils, were used to lower serum cholesterol, mortality increased, from a variety of causes including accidents, but mainly from cancer.
Since the l930s, it has been clearly established that suppression of the thyroid raises serum cholesterol (while increasing mortality from infections, cancer, and heart disease), while restoring the thyroid hormone brings cholesterol down to normal.
In this situation, however, thyroid isn’t suppressing the synthesis of cholesterol, but rather is promoting its use to form hormones and bile salts. When the thyroid is functioning properly, the amount of cholesterol in the blood entering the ovary governs the amount of progesterone being produced by the ovary, and the same situation exists in all steroid-forming tissues, such as the adrenal glands and the brain.
Progesterone and its precursor, pregnenolone, have a generalized protective function: antioxidant, anti-seizure, antitoxin, anti-spasm, anti-clot, anticancer, pro-memory, pro-myelination, pro-attention, etc. Any interference with the formation of cholesterol will interfere with all of these exceedingly important protective functions.
i got this stuff while doing research on coconut oil. laters pk
[quote]ScottL wrote:
Speaking of livers, how is yours? Didn’t you have elevated liver enzymes a while back?
As far as your question, are you referring to statins:
“The beneficial effects of statins are the result of their capacity to reduce cholesterol biosyntesis, mainly in the liver, where they are selectively distributed, as well as to the modulation of lipid metabolism, derived from their effect of inhibition upon HMG-CoA reductase”[/quote]
I have not gone for a blood test just yet. I have been on liver support supplements: livercare, inositol, milk thistle, l-methionine, tmg, l-carnitine, but i’ve started to run out of certain stuff. I’ll go soon and let you guys know.
the reason i waited was because i bulked up in july with the use of certain supplements and i’m finishing off my recovery/fatloss phase. after that i want to give my body a week atleast to cleanse out. laters pk
one treatment I’ve used and others around me have used is eating fresh Okinawan Spinach right off the plant or make a tea out of it. numbers go down pretty quick.
I do know that taking cholesterol lowering meds can often raise your liver function counts (AST, ALT, GGTP, etc.). So that would seem to make sense.
Taking statin drugs will kill you eventually. It’s not worth taking them. Just because you have high cholesterol, that doesn’t mean you’re more likely to die. In fact, if it gets too low, you’re more likely to die. What ya’ll really need to worry about is lipoprotein (a) or Lp(a) for short which is one of LDL substances proven to cause plaque leading to heart disease. As of now the only proven treatment for Lp(a) is take theurapic doses of vitamin C. We’re talking about 3-10, even 15g if it’s really bad a day divided in doses throughout the day as Vit C doesn’t last very long in the body. I think half life is like 30 mins long. Don’t worry about the pro oxidant effect. It’s baseless theory or study that they did. You have to understand that humans are one of the very few mammal species including ape, guinea pigs and few others lack one enzyme (out of 4) needed to convert blood glucose to Vit C in the liver. You’d be surprised how much those animals can produce their own Vit C. For example, a goat wieghing 140lbs or so, it can produce 3g a day under normal or nonstress conditions (sick, wounded, etc) up to 15g a day under stressful conditions. I have no doubt that if we had kept that enzyme that we somehow lost (unfortunate yet fortunate as it also controlled population growth for hundreds of thousands till recently. The population would have been alot more!) we’d produce that much amount of vit C and pretty much relatively free of cardivascular disease. There are more ways too but I’m not really in the mood to write another book at the moment. Maybe later today. Trust me cholesterol is not the true cause for cardiovascular disease at all. It’s merely a marker of what’s going on in the body. I would just forget about cholesterol and WORRY more about keeping insulin level under control!!! That is the MAIN factor for nearly ALL health problems! That’s what is happening in this country. …
Tungsten:
Do you have any recommendations for how much vitamin C to take in one sitting?
Right now I take 500mg, 3x a day. I’m not sure if it’s better to take more or less at one sitting, but I’m probably too lazy to take vitamins more than 3x a day.
Nick