Dhea should be higher, but I would get E2 to around 20 before changing anything else. Free t should be good if you get E2 down.
[quote]dhickey wrote:
Dhea should be higher, but I would get E2 to around 20 before changing anything else. Free t should be good if you get E2 down. [/quote]
You mean that I should aim for even higher DHEA-S than 318?
Higher DHEA net noticeable change zero. Way to much attention to these labs. You need to corral E2 and that’s it.
[quote]brentf13 wrote:
If you get your E2 in check free T will rise due to a decrease in SHBG. You should test for that. Adex is pretty difficult to dose and adjust. 5mg a day of Aromasin would do the trick. Aromasin is really easy to adjust.
If you really want to increase free T get some Proviron. [/quote]
would it make sense to keep anastrozole at 0.05mg/day and add aromasim, say 25mg/day? If 65% decrease in e2, my e2 level would drop from 47 to 16.5, or start with 12.5mg/day aromasim and check e2 level?
Or any reason not to use both AIs simultaneously? Dropping adex and starting aromasim would in effect mean starting the dosage adjustment from beginning…?
[quote]johnsmith1970 wrote:
[quote]brentf13 wrote:
If you get your E2 in check free T will rise due to a decrease in SHBG. You should test for that. Adex is pretty difficult to dose and adjust. 5mg a day of Aromasin would do the trick. Aromasin is really easy to adjust.
If you really want to increase free T get some Proviron. [/quote]
would it make sense to keep anastrozole at 0.05mg/day and add aromasim, say 25mg/day? If 65% decrease in e2, my e2 level would drop from 47 to 16.5, or start with 12.5mg/day aromasim and check e2 level?
Or any reason not to use both AIs simultaneously? Dropping adex and starting aromasim would in effect mean starting the dosage adjustment from beginning…?
[/quote]
Just use one or the other and adjust until you get E2 in the 20s. If you’re already using anastrozel, just keep making adjustments with that. You don’t want to start over.
I have tried to do some research about using both AIs simultaneously but haven’t found really any experience about it. What I have been thinking is to add small dose of aromasin, like 5mg/day in addition of anastrozole 0.1mg. As the action of these two is different there should not be complications? Also I’ve read that one should be used during cycle and one as part of pct. This would mean during cross over time both are effective.
Any thoughts?
You’re making this more complicated than it needs to be. Use one and adjust dose. Aromasin is used for PCT because it apparently works much better with SERMs than Anastrozel does. Tribal knowledge says Anastrozel doesn’t work well with SERMS.
Anastrozel is less expensive to run. Unless you have issues with it, just adjust dose and retest.
[quote]dhickey wrote:
You’re making this more complicated than it needs to be. Use one and adjust dose. Aromasin is used for PCT because it apparently works much better with SERMs than Anastrozel does. Tribal knowledge says Anastrozel doesn’t work well with SERMS.
Anastrozel is less expensive to run. Unless you have issues with it, just adjust dose and retest. [/quote]
Since my e2 was at 47 even after taking 0.05mg adex per day, I’m bit worried whether I get it down to 20ies with adex. That’s the main reason for considering adding aromasin to the mix.
[quote]johnsmith1970 wrote:
[quote]dhickey wrote:
You’re making this more complicated than it needs to be. Use one and adjust dose. Aromasin is used for PCT because it apparently works much better with SERMs than Anastrozel does. Tribal knowledge says Anastrozel doesn’t work well with SERMS.
Anastrozel is less expensive to run. Unless you have issues with it, just adjust dose and retest. [/quote]
Since my e2 was at 47 even after taking 0.05mg adex per day, I’m bit worried whether I get it down to 20ies with adex. That’s the main reason for considering adding aromasin to the mix.
[/quote]
That’s a tiny dose of adex. Up the dose a bit and retest. I needed .2mg per day for awhile. I ended up at .3mg EOD after dialing everything else in.
[quote]johnsmith1970 wrote:
Increased anastrozole yesterday to 1/210.5mg daily.
I also started peptides:
The compound is sermorelin 3mg - GHRP6 1.8mg - GHRP2 1.8mg / mL I have 4 vials ( each 3mL) of this compound and two refills after it. I’m bit confused what the dosage actually is. The instruction says 6 units using insulin pen (180mcg) daily.
So 3mL/0.18 = 16.667 dosages per vial. So 4 vials = 66.667 doses and 2 refills 66.66673 = 200 (I bought 6 months set) so seems ok.
In a vial I have:
Sermorelin 3mg3 = 9mg
GHRP6 1.8mg3 = 5.4mg
GHRP2 1.8mg*3 = 5.4mg
Thus daily dose:
Sermorelin 9mg /16.667 =0.54mg = 540mcg
GHRP6 5.4mg/16.667 = 324mcg
GHRP2 5.4mg/16.667 = 324mcg
Something here does not seem right. What I am doing wrong? Or is this right?
I think I could inject tree times a day, 2 units each time. One after waking up and one after training and one in the evening. Times so that I would not have eaten in about 2 hours and would not eat carbs and fats in next 30 min.
How this sounds?
I will also go and get blood test taken wednesday morning (T, Free T and Estradiol) so we’ll see how the results with anastrozole are.
Also how i should store the compound? And just reminder it is legit doctor prescribed stuff. [/quote]
I was recommeneded and am on the same protocol. + Vit D and HCG/MIC/B’s
I think I can help you maximize your workouts. honestly, you are spending way to much time training IMO> 1-1.5 hrs is too much and better results could be accomplished in 30-45 min. if interested, PM me
NASM-CPT, CrossFit L1, RKC Level 1 certified trainer
[quote]johnsmith1970 wrote:
I have tried to do some research about using both AIs simultaneously but haven’t found really any experience about it. What I have been thinking is to add small dose of aromasin, like 5mg/day in addition of anastrozole 0.1mg. As the action of these two is different there should not be complications? Also I’ve read that one should be used during cycle and one as part of pct. This would mean during cross over time both are effective.
Any thoughts?[/quote]
JS - I am using BTP also…
Just got the latest blood test results from 3/10 (in parenthesis results from 2/12, 1/29 and 1/15)
Testosterone: 735 (848, 553, 712) range 348 - 1197
Free testosterone: 20.5 (13.3, 10.7, 12.6) range 6.8 - 21.5
DHEA-S: 797.2 (318.7, 120.7, 225.2) range 102.6 - 416.3
Estradiol: 31.3 (47.0, 28.8, 36.1) range 7.6 - 42.6
PSA: 1.3 (1.2, 1.0 , 1.1) range 0.0 - 4.0
Same laboratory used every time. Same rest, fasting before test as well as same time of day 8:00AM.
Also I think I had sex each nigh before the tests (PSA?).
These after DHEA @ 50mg /day and anastrozole to 0.15mg /day and HCG 100UI every other day.
My plan is to keep the other stuff unchanged but reduce DHEA from 50mg/day to 25mg day. Comments welcome and appreciated as usual.
Looking good. You’re plan to go to 25mg DHEA is a good one. You might even be able to go down to 10mg. That should bring E2 down a bit too. If you can get DHEA and Free T towards the top of the range, and E2 in the 20s, you should be able to stop tweaking. If you’re still not feeling great, you can start to look elsewhere.
Just got the latest blood test results from 3/31 (in parenthesis results from 3/10, 2/12, 1/29 and 1/15)
Testosterone: 585 (735, 848, 553, 712) range 348 - 1197
Free testosterone: 11.5 (20.5, 13.3, 10.7, 12.6) range 6.8 - 21.5
DHEA-S: 277.4 (797.2, 318.7, 120.7, 225.2) range 102.6 - 416.3
Estradiol: 17.4 (31.3, 47.0, 28.8, 36.1) range 7.6 - 42.6
PSA: 1.3 (1.3,1.2, 1.0 , 1.1) range 0.0 - 4.0
Same laboratory used every time. Same rest, fasting before test as well as same time of day 8:00AM.
These after DHEA @ 25mg /day and anastrozole to 0.15mg /day and HCG 150UI E3D.
Haven’t felt too good. New plan: increase DHEA back to 50mg/day and increase anastrozole to 0.175mg/day and keep HCG at 150UI E3D.
(Last time with DHEA 50mg the only remaining that needed tuning seemed to be in getting estradiol lower).
Comments are welcome and appreciated as usual.
Looks like you need to up HCG a bit.
[quote]dhickey wrote:
Looks like you need to up HCG a bit.[/quote]
What you recommend?
With estradiol being 17… You don’t want or need to lower it…
Recommended HCG is 250-500 EOD or Biweekly…
[quote]Macmathews wrote:
With estradiol being 17… You don’t want or need to lower it…
[/quote]
Nope, but before lowering DHEA from 50mg to 25mg estradiol was much higher. And that time T and Free T were also much higher (Trying to keep T and Free T high and estradiol at about 20). Estradiol 17 maybe even bit too low.
250IU 3x/wk seems to be the sweet spot for me with HCG.