Bloodwork and TRT and Sermorelin/GHRP-6

your original numbers are great, I don’t see an issue for TRT. 712 Total T at 44, that’s higher then most 20 year olds now adays.
I’d try natural remedies of getting your estradiol down,
(50mg zinc, 300mg DIM, 2mg Copper) daily works for many
healthier eating(avoid processed foods, sugar, add sea salt to your food)
losing bodyfa
more explosive shorter duration workouts
to increase your Free T.

If you aren’t recovering as fast as you used to it’s because you’re 44, not because your hormones are messed up. IGF is at the top of the range, don’t worry about being 2-300 as labs use different ranges and you’re at the top of yours.

I wouldn’t mess with arimidex, seriosuly you seem to be getting greedy. If you want to be superman, do a cycle then pct. But your numbers look great overall, ESPECIALLY for your age. Don’t over complicate things either. Good luck and keep us updated.

HRT is a pain in the ass for most, wait until you really need it :slight_smile:

[quote]jomamma007 wrote:
your original numbers are great, I don’t see an issue for TRT. 712 Total T at 44, that’s higher then most 20 year olds now adays.
I’d try natural remedies of getting your estradiol down,
(50mg zinc, 300mg DIM, 2mg Copper) daily works for many
healthier eating(avoid processed foods, sugar, add sea salt to your food)
losing bodyfa
more explosive shorter duration workouts
to increase your Free T.

If you aren’t recovering as fast as you used to it’s because you’re 44, not because your hormones are messed up. IGF is at the top of the range, don’t worry about being 2-300 as labs use different ranges and you’re at the top of yours.

I wouldn’t mess with arimidex, seriosuly you seem to be getting greedy. If you want to be superman, do a cycle then pct. But your numbers look great overall, ESPECIALLY for your age. Don’t over complicate things either. Good luck and keep us updated.

HRT is a pain in the ass for most, wait until you really need it :)[/quote]

You are probably right. I’m getting greedy.

But on the natural remedies: I believe my diet is about as healthy as it can be:
Breakfast:

  • Oatmeal with:
    – 2 tbsp cold milled flaxseed
    – 1 tbsp bee pollen
    – 1 tbsp ground pumpkin seed
    – 1/3 cup blueberries
    – 0.5 tbsp honey
  • 5 egg whites, 1 whole egg + 1tbsp grape seed oil
  • 1/2 cup pomegranate juice
  • Calcium (1200mg) +d3 vitamin (1000IU)
  • Selenium (200mcg)
  • Magnesium (400mg)

3 pre-prepared meals (self made)

  • One with Salmon or Tuna, one with chicken breast, one with 95% fat free ground beef
    Sides: Blackeye Peas, Black Beans, Red Kidney Beans,Pinto Beans, Green Beans Fresh, Organic Baby Spinach, Quinoa, Plum Tomato, Asparagus, Brown Rice Long Grain, Broccoli Raw, Organic Mild Salsa, Extra Virgin Olive Oil
    Each meal about 450-550cal

0-1 extra meal either turkey breast or tenderloin with Sauer Kraut, spinach, Cabbage, Beets

Supplements:

  • Zinc (50mg mid day, 50 mg before bed)
  • Magnesium (400mg, before bed)
  • Melatonin (2*3mg before bed)
  • Floradix iron + herbs (2*12ml, mid day and before bed)
  • Potassium 595mg (mid day)
  • Ginseng 648mg twice a day
  • CLA 2*1250mg twice a day
  • Fish Oil 2*1200mg twice a day
  • Vitamin E 400UI
  • CoQ10 10mg
  • L-argine 500mg
  • L-citrulline 2*750mg
  • DIM 2-4* 100mg
  • Will probably start DHEA 25mg

Before bed protein shake:

  • Gnc Pro Performance - 100% Casein Protein Chocolate, 2 Level Scoop 42g
  • Gnc - Xr Series Bcaa Advance Xr, 2 scoop
  • Met-Rx - L-Glutamine Powder, 2 scoop (5g)

About 1/4-1/2 cup of cashew nuts, brazil nuts, pistachios, pumpkin seeds, almonds

List of supplements is quite long, would probably cut down and leave only :wink: :

  • Zinc (50mg mid day, 50 mg before bed)
  • Magnesium (400mg, before bed)
  • Melatonin (2*3mg before bed)
  • Floradix iron + herbs (2*12ml, mid day and before bed)
  • Potassium 595mg (mid day)
  • CLA 2*1250mg twice a day
  • Fish Oil 2*1200mg twice a day
  • CoQ10 10mg
  • DIM 2-4* 100mg
  • DHEA 25mg

No processed foods

Although not in correct forum, but comments on the diet are welcome.

On training:
I do deadlifts and squats twice a week each with 7 sets (20-4 reps each). It takes about an hour to do squats and deadlifts. Bent over rows, bench press, shoulder presses 3 times a week (7 sets each)

  • isolation exercises. Each training session is about 1-1.5 hours and I train on 3 days per week, twice per day (total training per training day about 2.5-3.5h). I know this is lot, but my progress is quite stellar.

Generally men should not take extra iron unless they have a documented deficiency. It is bad for cardiovascular health in the long run. That is the reason why multivitamin formulations targeted at men have no iron. It is also a reason why men are often encouraged to donate blood, to reduce iron levels.

DHEA will probably only raise your estrogen levels. In men DHEA tends to convert preferentially into estrogens. DHEA itself can be considered an estrogen as it activates some estrogen receptors as strongly as estradiol itself.

Learn all the time new things :wink: My hemoglobin was bit low (14.9g/dL) in December and I started taking Iron to increase it, Jan 15th it was 15.4g/dL still bit on the low end. Optimal range is about 15-18. When I was young my hemoglobin used to be really high (17.4g/dL).

DHEA I wouldn’t take without anastrozole.

Increased anastrozole yesterday to 1/210.5mg daily.
I also started peptides:
The compound is sermorelin 3mg - GHRP6 1.8mg - GHRP2 1.8mg / mL I have 4 vials ( each 3mL) of this compound and two refills after it. I’m bit confused what the dosage actually is. The instruction says 6 units using insulin pen (180mcg) daily.
So 3mL/0.18 = 16.667 dosages per vial. So 4 vials = 66.667 doses and 2 refills 66.6667
3 = 200 (I bought 6 months set) so seems ok.
In a vial I have:
Sermorelin 3mg3 = 9mg
GHRP6 1.8mg
3 = 5.4mg
GHRP2 1.8mg*3 = 5.4mg

Thus daily dose:
Sermorelin 9mg /16.667 =0.54mg = 540mcg
GHRP6 5.4mg/16.667 = 324mcg
GHRP2 5.4mg/16.667 = 324mcg

Something here does not seem right. What I am doing wrong? Or is this right?

I think I could inject tree times a day, 2 units each time. One after waking up and one after training and one in the evening. Times so that I would not have eaten in about 2 hours and would not eat carbs and fats in next 30 min.

How this sounds?

I will also go and get blood test taken wednesday morning (T, Free T and Estradiol) so we’ll see how the results with anastrozole are.

Also how i should store the compound? And just reminder it is legit doctor prescribed stuff.

At least at some level this stuff is working. Last night I slept most deep ever. Unfortunately it came with one side effect. I have been taking casein protein just before going to bed. This has caused me to wake up and pee multiple times per night. I have thought about starting to take the casein a little earlier so that I could pee before going to bed instead of waking up 3-4 times per night. We’ll last night I slept uninterrupted 5+ hours and found out that I had peed a bit in the bed :frowning: - and this is first time ever I can remember that happening. My dreams were quite vivid.

Also my urine seemed to be darker than normally in the morning and early parts of the day - causing some nervousness for me. Now urine is normal. The plan for this evening and night: take casein about 1-2 hours before going to bed. I can’t rate recovery yet, hope it is better.

That sounds about right on peptides for a cycle. Odd that you’re doubling up on GHRPs though. I’m taking Mod GRF and GHRP-2 at 100mcg per. I take it at night and am sleeping much better, which is huge for me. Might eventually dial it down to just what I need to sleep, but I’m trying to eliminate other meds/supps for sleep first.

[quote]dhickey wrote:
That sounds about right on peptides for a cycle. Odd that you’re doubling up on GHRPs though. I’m taking Mod GRF and GHRP-2 at 100mcg per. I take it at night and am sleeping much better, which is huge for me. Might eventually dial it down to just what I need to sleep, but I’m trying to eliminate other meds/supps for sleep first.[/quote]

What you mean by doubling GHRPs? Having both GHRP6 and GHRP2? I didn’t make the mix or design it. It’s what my doctor prescribed and pharmacy mixed…

If my calculations are correct I’m taking
100mcg GHRP2 and GHRP6 3 times a day
and
180mcg Sermorelin (GFR 1-29)3 times a day.
From what I’ve read it seems reasonable to have both GHRPs, but really I have no idea just following the instructions (okay, instructions were to inject once a day 6 units and I am injecting 2 units 3 times a day).

This stuff is from one of aging clinics…

Are you taking the stuff just before going to sleep? Or bit earlier? Taking it just before sleep seems a bit waste for me as isn’t it so that you get your natural peak a little after you fall asleep and you don’t want to mess with that?

Peptides increase your bodies natural output. It makes sense to time it with natural peaks like at night or after workouts.

HGH is suppressive, so most take in the morning to minimize disruption of the natural release at night. Not as familiar with HGH, but that’s what I’ve read.

[quote]dhickey wrote:
Peptides increase your bodies natural output. It makes sense to time it with natural peaks like at night or after workouts.

HGH is suppressive, so most take in the morning to minimize disruption of the natural release at night. Not as familiar with HGH, but that’s what I’ve read.[/quote]
Yeah, my thought was probably from HGH.

Hey JS,
Are you using BTP for this whole thing ?

[quote]PKNY wrote:
Hey JS,
Are you using BTP for this whole thing ? [/quote]
What’s BTP?

Initials of the provider/clinic you are using.

[quote]PKNY wrote:
Initials of the provider/clinic you are using.[/quote]
Nope. SRC.

Had my blood test taken this morning. Can’t wait to see the results. My diet has not been as clean as possible during the last week because of the things beyond my control but it has been quite ok anyhow. This test is only for T, free T, Estradiol, DHEA-S and PSA. Test was done at same time of the day and morning after a rest day with same fasting period and by the same laboratory (labcorp), so the results should be as much as possible comparable to the earlier. Results should be ready in couple of days.

I didn’t sleep super tight last night but ok anyhow.

I just realized that one thing has definitely changed after starting peptides (in two days). I had some shoulder pain on my right shoulder and sometimes on my right elbow and forearm feeling that the blood does not circulate well. Today I haven’t had any of that feeling. Don’t know if this is a real effect or temporary and unrelated, but the mild pain during exercise has been constant for about two weeks and now gone.

Just got the blood test results from 1/29 (in parenthesis results from 1/15)
Testosterone: 553 (712) range 348 - 1197
Free testosterone: 10.7 (12.6) range 6.8 - 21.5
DHEA-S: 120.7 (225.2) range 102.6 - 416.3
Estradiol: 28.8 (36.1) range 7.6 - 42.6
PSA: 1.0 (1.1) range 0.0 - 4.0

Same laboratory used both times.

Strange:
T and free T could be down due to overtraining?
DHEA-S seems low to me => Start taking DHEA supplements?
Estradiol is down a bit => increase Anastrozole dosage quite a bit?

[quote]johnsmith1970 wrote:
Just got the blood test results from 1/29 (in parenthesis results from 1/15)
Testosterone: 553 (712) range 348 - 1197
Free testosterone: 10.7 (12.6) range 6.8 - 21.5
DHEA-S: 120.7 (225.2) range 102.6 - 416.3
Estradiol: 28.8 (36.1) range 7.6 - 42.6
PSA: 1.0 (1.1) range 0.0 - 4.0

Same laboratory used both times.

Strange:
T and free T could be down due to overtraining?
DHEA-S seems low to me => Start taking DHEA supplements?
Estradiol is down a bit => increase Anastrozole dosage quite a bit?
[/quote]

Not a huge swing in Free T, so I wouldn’t read too much into it. If it were me, I would get DHEA up quite a bit. I’d start with transdermal magnesium to see if that works for you. you’ll probably need to supplement DHEA directly to get towards the top of the range. Find micronized. Lef.org worked really well for me at 25mg per day. You might need 50mg. I’m guessing that will increase Free T. E2 is probably ok if you get Free T up. You could lower it a bit more I guess. If you end up taking DHEA, E2 might increase a bit.

Few opinions:

  1. Peps are not that great. Run HGH and you’ll see what I mean. Huge difference.
  2. Adex, in my experience, is inferior to Aromasin. Aromasin is way easier to dose and my labs have been much more consistent.
  3. Blood labs are worthless for initial diagnosis. They’re a snap shot in time on one specific day. Run a 24 hour urine panel. Way more accurate. For example my morning blood labs would be mid range but the 24 hour panel showed my daily output was bottom of the range.
  4. Whoever prescribed you TRT with a TT of 700+ is insane. The fact that they prescribed it as a cycle is even more insane!

If you need it TRT is great. If you don’t need it why mess with your health? Dump the peps. They’re a joke.

Thanks.

  • I increased anastrozole dosage from 1/210.5mg/day to 1/100.5mg per day
  • I started taking 50mg micronized DHEA daily

I had started feeling gradually more tired and last weekend I was barely able to get up from the bed. My body temp was low, not getting over 96.5 and was even below 96 in the mornings. I read about thyroid basics from this site and while my thyroid hormones (TSH, T3 and T4) were all at the ideal values, I’m pretty sure I have Iodine deficiency. I haven’t used iodized salt nor any iodine supplements. I used to eat a bit sushi (seaweed) but haven’t eaten much of that in last 6 months. I started taking iodoral 4*12.5mg per day and my temp has risen a little bit, it’s about 97.7-98 in the afternoon.

I also think that my training was too intense and I did not recover from it and that started to take the toll on my body. Hope it was just the iodine deficiency, but frankly I think 1.5hours 2 sessions per day 3 days per week was too much.

I haven’t taken T injections and if I will start those I’ll collect more them and take a cycle (400mg/ week for 10 weeks). But as of now I try to optimize Estradiol and Free T levels with anastrozole and DHEA and see after that what needs to be done. I will probably get new bloodtest taken next wednesday morning.

I wanted to get HGH but they were not able to prescribe it to me based on the blood test results (I also wonder how they prescribed T…).

Just got the latest blood test results from 2/12 (in parenthesis results from 1/29 and 1/15)
Testosterone: 848 (553, 712) range 348 - 1197
Free testosterone: 13.3 (10.7, 12.6) range 6.8 - 21.5
DHEA-S: 318.7 (120.7, 225.2) range 102.6 - 416.3
Estradiol: 47.0 (28.8, 36.1) range 7.6 - 42.6
PSA: 1.2 (1.0 , 1.1) range 0.0 - 4.0

Same laboratory used every time. Same rest, fasting before test as well as same time of day 8:00AM.
Also I think I had sex each nigh before the tests (PSA?).

Total T level quite ok (bit higher than 95th percentile for 40-49 year old males as described in Clinical Endocrinology (2005) 62, 64-73), Free T should be higher (below 50th percentile), and definitely Estradiol is too high.

This after being taking micronized DHEA 50mg and 0.05mg anastrozole each day.

Plan for next adjustment, keep DHEA @ 50mg /day and increase anastrozole to 0.1mg /day (should I increase it even more?).

Comments are very welcome as always.

If you get your E2 in check free T will rise due to a decrease in SHBG. You should test for that. Adex is pretty difficult to dose and adjust. 5mg a day of Aromasin would do the trick. Aromasin is really easy to adjust.

If you really want to increase free T get some Proviron.