I would add the CJC-IPAM man. Telling you, it is great stuff and it is not suppressive. I am a BIG believer in combining T optimization with GH optimization.
Once you get that right, you don’t need to do anything else. This is why I advocate against deca.
Your program sounds like it is going well, sounds like you are not abusing things and that is the way it is supposed to be.
But remember this. Think of any kind of androgen or anabolic use as sand in an hourglass. This sand gets used every time you use an androgen. Some androgens cost you more sand than others. Higher dosages cost you more sand than lower dosages. Some people start with more sand then the next guy.
Use your sand wisely. Masteron is weak and very androgenic.
This is why I love GH optimization so much, it reduces inflammation and actually helps to protect the heart. While making you more sensitive to the T you already have. And your not using any sand.
deca (nandrolone) is actually harsher on the heart be it through different mechanisms. A compound not as harsh on the heart (probably) would be metenolone. Androgen receptor binding likely has more of an effect on the myocardium as androgens exhibit a large portion of hypertrophic stimuli through AR binding, cardiac myocytes contain androgen receptors and thus one could link two and two together. Oxandrolone isn’t a strong androgen but binds to the androgen receptor VERY strongly.
I’ve seen the study you quoted. it was the one I was thinking of, the full literature can be viewed here
It should be noted the average dose was 675, the minimum INCLUSION REQUIREMENT for the study was to have used anabolics for at least two years, furthermore in the graphs presented within the study one can see almost all participants had used fro well more than two years, some approaching 30 years, this is cumulative lifetime exposure, not sole use. Two years of cumulative exposure equates to 104 weeks on 675mg/wk, otherwise closer to 10-11 cycles. Furthermore variables such as lifestyle, drug use, genetics etc, many of the subjects were alcohol or cocaine dependent which when combined with AAS equates to a far harsher impact on the heart, thus potentially skewing results. However the results are nonetheless significant and demonstrate the impact chronic AAS abuse can have on the heart.
Furthermore testosterone in itself, dosed high enough over long periods of time can absolutely have detrimental effects on the myocardium, kidneys, haematological parameters etc. AAS cause injury to the myocardium through indirect and direct mechanism, negating the indirect mechanisms can amoreliate long term harm somewhat (high blood pressure and increased uptake, release and sensitivity to catecholamines particularly) however there’s no denying one is taking a significant risk long term when using doses of 675mg
Big smiles from my side of the computer. I am a big peptide and sarms user.
I started out using Sermorelin at 1000mcg taken at bed time. Only to find out 6 months later it does not work for guys over 60 so I added Ipmaorelin at 500 mcg at bedtime. It took my IGF-1 from 99 to 160 in 6 months. I have since dropped the sermorelin and only use the Ipmaorelin at 500mcg at bedtime. I have not done bloods to see where my IGF-1 is. At my age of 67 I am looking for a IFG-1 of 200. What are your thoughts?
So let’s say someone did 250 mg for 200 weeks, 4 years. Do you think this is going to lead to issues down the road? Or do you think it is possible to do that for say 5 years straight, no breaks, and have a good lipid profile and not reduce the strength of your heart?
You use sarms? There’s like little no data on them when used in the doses people use for bodybuilding, they appear (anecdotally) to fuck up you’re lipid profile just as bad as c17AA AAS
depends on where 250mg gets them too, if they’re mildly, mildly supraphysiologic (say TT of 1300-1400 FT 1.25x ref range) on cavg and they’re young, athletic with good genetics and live a healthy lifestyle. Aside from high HCT/RBC (potentially, once again a genetic predeterminant and if OP donates blood regularly it probably wouldn’t become an issue). I think there’s the possibility it might not be particularly damaging.
But then again how many guys use doses like that for such long periods of time… Unless you’re a professional bodybuilder or very large I don’t think you’d be cruising on 250
Exactly, I’m saying there’s a small chance it won’t do significant damage. We have to remember the lifestyle of someone who would do something like this. If they’re running a 5k every day, working out 6 days per week, eating healthily, keeping up to date with labs and gets regular checks in regard to cardiovascular health, say a regular EKG to make sure nothing is going wrong (and then ceasing use when something does go awry) chances are the dude will be fine as he will stop once he notices damage is starting to occur.
So thats what @dbossa is not willing to admit. He makes it sound as if since it is testosterone and not a derivative that lab numbers don’t mean anything if you feel good.
He has said those exact words. That is what got me all riled up.
I’d say testosterone isn’t as dangerous as running other synthetics. For instance if you run 100mg test/wk and 20mg dbol/day for years on end you’re bound to wind up in a whole lot more trouble than test
100mg test 100mg tren you’re in heaps more trouble
100mg test 100mg eq you’re in more trouble (esp regarding kidneys)
And I am glad you mentioned this, because I think this is why we don’t see more of the end stage failure. People quit before it gets that bad, or they lower their dosage.
so as a practitioner if someone came to you telling you they were on steroids, would you feel comfortable monitoring their health parameters or would you tell them to get out?
In Aus, they’ll tell you to get out then write it on you’re permanent medical record after a very long lecture
My lipids are great I am on a new PC and can’t access my bloods but I will show you my before and after. I have cut my lipids in half from being in the red to all normal. It was from cutting all omega 6 oils and adding omega 3s. I have fell in love with the peptides CJC 1295, and Ipamorelin and the sarms Cardarine. I don’t care what the research says theses supplements to my TRT protocol have had results I see in the mirror.
@bmbrady77
You do realize increasemyt is basically dbossa but repping a protocol more similar to what works for you. I appreciate him being here. Dbossa as well. I kept my free T in range for a long time and never felt decent. I get it. If a free T of 20 made me feel amazing I’d be saying the same shit about dbossa but it didn’t. When I worked from 100mg to 200mg over the course of a year I finally felt like a human being able to live a normal life. I have no dog in this fight. I enjoy the arguments. Otherwise it turns into a club where people will defend at all cost the loudest mouth in the room. I tried all ksman’s shit and I wish it wasn’t promoted as gospel. Would have saved me several E2 crashes. And let me say I appreciate your info as well. You’ve helped me on several occasions.
Cardarine isn’t sarm it’s a PPAR receptor agonist, be careful with that one. Data on carcinogenicity regarding that compound is scary and is the sole reason I’ve never used it
Stay away from LDG, OSTARINE and the likes if you can help it though, at least for the timebeing until we have a better grasp as to the safety profile of the compounds
I’d try CJC however I see no reason for me to need to increase my GH output. I have reason to believe as a child I potentially didn’t produce all that much GH (not that I was deficient per se, however my mother was 5’5 my father was 5’8 and I ended up a tad under 5’5, never went through a rapid growth spurt (grew steadily and slowly) etc.
Given that I’m so young I feel as if GH manipulation certainly isn’t a field I need to tinker with yet
Ahhh yess but I wasn’t put on TRT until I was 17, testosterone certainly decreases final adult height if given to children, however my ephysical plates had fully fused by the time I was put on
My case was very complex and was an ordeal I do not wish to go through again, it’s a long story