From Micheal Eades’ latest post:
"Since the most primitive organisms not using photosynthesis to obtain energy used the stored glucose and starch from those that did, it?s no wonder that we evolved with a primitive basic need for glucose as a sort of primary fuel.
But the fact that we don?t need to consume glucose and/or its storage form, starch, directly despite our requiring it for life is strong evidence that we had a meat-eating past. Let me explain.
Natural selection is a harsh taskmaster, one that rigorously weeds and trims systems back that aren?t required for optimal performance of the creature in question. If, for example, a specific organism requires substance X for life and there is no substance X in the environment of this organism, then the organism will have developed the metabolic machinery to convert whatever is at hand to substance X.
If it doesn?t and it has no substance X, then it dies, so it has to have a means to synthesis substance X. The processes that synthesize substance X require energy, but it?s worth the expenditure of this energy because if there is no substance X made, there is no life. The energy used to synthesize substance X is then not available for other uses and the organism budgets accordingly.
Now let?s say that our substance X-requiring organisms migrate to an area that is rich in substance X. They no longer have to make it?they can simply consume it. But all the machinery is there within them to make it, consuming energy. Sooner or later somewhere along the way one of these organisms is going to be born with a mutation in its substance X synthesizing machinery.
In the days before the vast fields of substance X were available that all these organisms are now feeding on, this mutation would have been fatal. But now it provides a huge metabolic advantage.
While all the other organisms are feeding on substance X and spending energy to run their own substance X-synthesizing pathways, the organism with the mutation can use that energy elsewhere giving it a powerful edge in the reproductive sweepstakes.
Over time all these organisms will evolve to the point to which none of them have to waste energy on the internal machinery to make substance X. When scientists study these organisms later on, they will call substance X vitamin X because it is essential to life for these creatures and they can?t make it themselves.
Getting back to us, we realize that we have all the internal biochemical machinery to make glucose out of protein and out of the glycerol from disassembled fat (triglycerides), but we have no machinery to make amino acids (the building blocks of protein) and no machinery to make the essential fats. These essential amino acids and these essential fats have to come from our diet.
And we can to a certain extent replace glucose with ketones, which come from the partial breakdown of fat in the liver.
So, we need glucose for many cellular processes simply because of our primitive systems dating back millions of years that evolved when glucose was really the only food available. But we?ve evolved ways to make glucose out of fat and protein and evolved a method to replace some of the glucose by ketones, which are a fat by product.
What this should tell us is that over the recent past of our evolutionary history protein and fat have been readily available and glucose may not have been. Where do we get protein and fat? The main source for both is meat.
Obviously in our Paleolithic past (and before) we had plenty of meat and not much starch, otherwise we would have evolved differently. If we had evolved in a situation in which we had plenty of starch and no meat, we would have evolved a way to make protein out of carbs (which we can?t) and essential fat out of carbs (which we can?t). The fact that we are structured the opposite tells us the real story.
And should lead us to reckon that if we evolved eating primarily meat and not much, if any, plants that we are fine tuned metabolically to operate optimally on such a diet. Which is the reason a low-carb diet works so well to reverse the diseases caused by eating in the reverse of our evolutionary heritage."
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