Recent CDC study:
Our method can measure E2 and TT in samples from children, women and men. We measured the total testosterone and estradiol in 250 individual sera from male and female donors (Table 5). In adult males age 18 years and older, serum TT concentrations ranged from 0.62 to 32.5 nM (18.0 ng/dL to 938 ng/dL), and E2 concentrations ranged from 17.3 to 167 pM (4.72–45.6 pg/mL). In women age 18 to 59 years, TT concentrations ranged from 0.28 to 2.55 nM (8.03 to 73.6 ng/dL), and E2 concentrations ranged from 11.4 to 12357 pM (3.11 to 3367 pg/mL). Among women age 60 years and older, TT concentrations ranged from 0.26 to 4.13 nM (7.54 to 119 ng/dL), and E2 levels ranged from 9.25 to 1152 pM (2.52 to 314 pg/mL). In children at 6–11 years of age, 90% of boys had E2 levels below 11 pM (3 pg/mL), while in girls the E2 concentrations ranged from 2.39 to 177 pM (0.65–48.3 pg/mL). TT levels were detectable in all 100 samples from children, with boys had much broader range (0.03–12.6 nM (0.77–363 ng/dL)) comparing to girls (0.04–0.85 nM (1.07–24.6 ng/dL)